Journal ArticleDOI
Biodegradable polymeric nanoparticles as drug delivery devices
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TLDR
This review presents the most outstanding contributions in the field of biodegradable polymeric nanoparticles used as drug delivery systems from 1990 through mid-2000.About:
This article is published in Journal of Controlled Release.The article was published on 2001-01-29. It has received 3284 citations till now. The article focuses on the topics: Drug carrier & Drug delivery.read more
Citations
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Biodegradable nanoparticles for direct or two-step tumor immunotargeting.
TL;DR: Experiments have shown that NPs covalently coupled with antibodies or NAR can specifically and efficiently bind to cancer cells in both a pretargeting and a direct approach, suggesting that functionalized NPs may be a useful drug carrier for tumor targeting.
Journal ArticleDOI
Functionalized Gold Nanoparticles for Applications in Bionanotechnology
TL;DR: The optical and chemical properties of gold nanoparticles are described, and a number of specific applications within bionanotechnology are reviewed.
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Chitosan-based nanoparticles: An overview of biomedical applications and its preparation
TL;DR: This review presents different preparation methods of chitosan nanoparticles (CSNPs) from the methodological and mechanistic point of view and why CS has been chosen to design nanoparticles as drug delivery systems in various pharmaceutical applications.
Journal ArticleDOI
Influence of nanoencapsulation on human skin transport of flufenamic acid.
J. Luengo,Barbara Weiss,Marc Schneider,Alexander Ehlers,Frank Stracke,Karsten König,Karl-Heinz Kostka,Claus-Michael Lehr,Ulrich F. Schaefer +8 more
TL;DR: In this article, the authors investigated the effect of the inclusion of flufenamic acid in poly(lactide-co-glycolide) nanoparticles on the transport of the acid into excised human skin.
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Novel self-assembled core-shell nanoparticles based on crystalline amorphous moieties of aliphatic copolyesters for efficient controlled drug release.
TL;DR: Among the main advantages of the nanoparticles produced in this study is the absence of burst effect during drug release.
References
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Journal ArticleDOI
Biodegradable long-circulating polymeric nanospheres
Ruxandra Gref,Yoshiharu Minamitake,Maria Teresa Peracchia,Vladimir S. Trubetskoy,Vladimir P. Torchilin,Robert Langer +5 more
TL;DR: Monodisperse biodegradable nanospheres were developed from amphiphilic copolymers composed of two biocompatible blocks and exhibited dramatically increased blood circulation times and reduced liver accumulation in mice.
Journal ArticleDOI
Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
Journal ArticleDOI
Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers
TL;DR: In this paper, a new approach for the preparation of nanoparticles made solely of hydrophilic polymers is presented, based on an ionic gelation process, is extremely mild and involves the mixture of two aqueous phases at room temperature.
Journal ArticleDOI
Protein—surface interactions in the presence of polyethylene oxide
TL;DR: In this paper, the steric repulsion free energy and van der Waals attraction free energy of polyethylene oxide (PEO) chains were calculated as a function of surface density and chain length of PEO.
Book
Principles of tissue engineering
TL;DR: The history and Scope of Tissue Engineering, J.P. Vavanti and C.A. Vacanti, and Quantitative Aspects of Tissues Engineering: Basic Issues in Kinetics, Transport, and Mechanics are reviewed.
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