Open Access
Features, Evaluation and Treatment Coronavirus (COVID-19)
TLDR
The effects of the epidemic caused by the new CoV has yet to emerge as the situation is quickly evolving, and world governments are at work to establish countermeasures to stem possible devastating effects.Citations
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Biological Properties of SARS-CoV-2 Variants: Epidemiological Impact and Clinical Consequences
Reem Hoteit,Hadi M. Yassine +1 more
TL;DR: Key information is examined and provided on SARS-CoV-2 VOCs, including their transmissibility, infectivity rate, disease severity, affinity for angiotensin-converting enzyme 2 (ACE2) receptors, viral load, reproduction number, vaccination effectiveness, and vaccine breakthrough.
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A mathematical model of COVID-19 transmission in a tertiary hospital and assessment of the effects of different intervention strategies.
Yae Jee Baek,Taeyong Lee,Yunsuk Cho,Jong Hoon Hyun,Moo Hyun Kim,Yujin Sohn,Jung Ho Kim,Jin Young Ahn,Su Jin Jeong,Nam Su Ku,Joon Sup Yeom,Jeehyun Lee,Jun Yong Choi +12 more
TL;DR: It is suggested that the early testing of infected cases and monitoring the quarantine ward for newly hospitalized patients are effective measures for decreasing the incidence of COVID-19 within a hospital and the implementation of the preventive measures could reduce the size of a hospital outbreak.
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A Novel Perspective Approach to Explore Pros and Cons of Face Mask in Prevention the Spread of SARS-CoV-2 and other pathogens.
M.D. Faruque Ahmad,Shadma Wahab,Fakhruddin Ali Ahmad,M. Intakhab Alam,Hissana Ather,Ayesha Siddiqua,Syed Amir Ashraf,Mohammad Abu Shaphe,Mohammed Idreesh Khan,Rashid Ali Beg +9 more
TL;DR: According to latest updates face shield and social distancing could be better substitute of face mask as mentioned in this paper, face mask could be risk for the people of under lying medical conditions, old age group, outdoor exercise, acute respiratory disorders and feeble innate immune.
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Pharmaconutrition in the Clinical Management of COVID-19: A Lack of Evidence-Based Research But Clues to Personalized Prescription
TL;DR: There is currently no evidence of the utility of any nutritional strategies in the management of SARS-CoV-2 infection and COVID-19, Nevertheless, ongoing and future clinical research is imperative to determine if any pharmaconutrition strategies can halt the progression of CO VID-19.
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No evidence of vertical transmission of SARS-CoV-2 after induction of labour in an immune-suppressed SARS-CoV-2-positive patient.
Koen Grimminck,Lindy Anne Maria Santegoets,Frederike Charlotte Siemens,Pieter L.A. Fraaij,Irwin Karl Marcel Reiss,Sam Schoenmakers +5 more
TL;DR: A case of a 38+1 weeks pregnant patient (G1P0) with a proven COVID-19 infection, who was planned for induction of labour because of pre-existent hypertension, systemic lupus erythematosus, respiratory problem of coughing and mild dyspnoea without fever during the CO VID-19 pandemic in March 2020 is presented.
References
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Journal ArticleDOI
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Markus Hoffmann,Hannah Kleine-Weber,Simon Schroeder,Nadine Krüger,Tanja Herrler,Sandra Erichsen,Tobias S. Schiergens,Georg Herrler,Nai Huei Wu,Andreas Nitsche,Marcel A. Müller,Christian Drosten,Christian Drosten,Stefan Pöhlmann +13 more
TL;DR: It is demonstrated that SARS-CoV-2 uses the SARS -CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming, and it is shown that the sera from convalescent SARS patients cross-neutralized Sars-2-S-driven entry.
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Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine.
Fernando P. Polack,Stephen J. Thomas,Nicholas Kitchin,Judith Absalon,Alejandra Gurtman,Stephen Lockhart,John L. Perez,Gonzalo Pérez Marc,Edson D. Moreira,Cristiano Zerbini,Ruth Bailey,Kena A. Swanson,Satrajit Roychoudhury,Kenneth Koury,Ping Li,Warren Kalina,David A. Cooper,Robert W. Frenck,Laura L. Hammitt,Özlem Türeci,Haylene Nell,Axel Schaefer,Serhat Ünal,Dina B. Tresnan,Susan Mather,Philip R. Dormitzer,Ugur Sahin,Kathrin U. Jansen,William C. Gruber +28 more
TL;DR: A two-dose regimen of BNT162b2 conferred 95% protection against Covid-19 in persons 16 years of age or older and safety over a median of 2 months was similar to that of other viral vaccines.
Journal ArticleDOI
Acute respiratory distress syndrome: the Berlin Definition.
Ards Definition Task Force,V. Marco Ranieri,Gordon D. Rubenfeld,B. Taylor Thompson,Niall D. Ferguson,Ellen Caldwell,Eddy Fan,Luigi Camporota,Luigi Camporota,Arthur S. Slutsky +9 more
TL;DR: The updated and revised Berlin Definition for ARDS addresses a number of the limitations of the AECC definition and may serve as a model to create more accurate, evidence-based, critical illness syndrome definitions and to better inform clinical care, research, and health services planning.
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Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1.
Neeltje van Doremalen,Trenton Bushmaker,Dylan H. Morris,Myndi G. Holbrook,Amandine Gamble,Brandi N. Williamson,Azaibi Tamin,Jennifer L Harcourt,Natalie J. Thornburg,Susan I. Gerber,James O. Lloyd-Smith,Emmie de Wit,Vincent J. Munster +12 more
TL;DR: Aerosol and Surface Stability of SARS-CoV-2 In this research letter, investigators report on the stability of Sars-CoVs and the viability of the two virus under experimental conditions.
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
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