Open Access
Features, Evaluation and Treatment Coronavirus (COVID-19)
TLDR
The effects of the epidemic caused by the new CoV has yet to emerge as the situation is quickly evolving, and world governments are at work to establish countermeasures to stem possible devastating effects.Citations
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Journal ArticleDOI
An inflammatory cytokine signature predicts COVID-19 severity and survival.
Diane Marie Del Valle,Seunghee Kim-Schulze,Hsin-Hui Huang,Noam D. Beckmann,Sharon Nirenberg,Bo Wang,Yonit Lavin,Talia H. Swartz,Deepu Madduri,Aryeh Stock,Thomas U. Marron,Hui Xie,Manishkumar Patel,Kevin Tuballes,Oliver Van Oekelen,Adeeb Rahman,Patricia Kovatch,Judith A. Aberg,Eric E. Schadt,Sundar Jagannath,Madhu Mazumdar,Alexander W. Charney,Adolfo Firpo-Betancourt,Damodara Rao Mendu,Jeffrey S. Jhang,David Reich,Keith Sigel,Carlos Cordon-Cardo,Marc Feldmann,Samir Parekh,Miriam Merad,Sacha Gnjatic +31 more
TL;DR: It is proposed that serum IL-6 and TNF-α levels should be considered in the management and treatment of patients with COVID-19 to stratify prospective clinical trials, guide resource allocation and inform therapeutic options.
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Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study.
Lei Pan,Lei Pan,Mi Mu,Pengcheng Yang,Yu Sun,Runsheng Wang,Junhong Yan,Pibao Li,Baoguang Hu,Jing Wang,Chao Hu,Yuan Jin,Xun Niu,Rongyu Ping,Yingzhen Du,Tianzhi Li,Guogang Xu,Qinyong Hu,Lei Tu +18 more
TL;DR: It is found that digestive symptoms are common in patients with COVID-19 and that the index of suspicion may need to be raised earlier in at-risk patients presenting with digestive symptoms, but further large sample studies are needed to confirm these findings.
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Coronavirus Disease 2019–COVID-19
Kuldeep Dhama,Khan Sharun,Ruchi Tiwari,Shubhankar Sircar,Sudipta Bhat,Yashpal Singh Malik,Karam Pal Singh,Wanpen Chaicumpa,D. Katterine Bonilla-Aldana,Alfonso J. Rodriguez-Morales +9 more
TL;DR: Analysis of epidemiological, diagnostic, clinical, and therapeutic aspects, including perspectives of vaccines and preventive measures that have already been globally recommended to counter this pandemic virus, suggest that this novel virus has been transferred from an animal source, such as bats.
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"Pandemic fear" and COVID-19: mental health burden and strategies.
TL;DR: ‘‘Pandemic fear’’ and COVID-19: mental health burden and strategies
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A Comprehensive Review of the COVID-19 Pandemic and the Role of IoT, Drones, AI, Blockchain, and 5G in Managing its Impact
TL;DR: The use of technologies such as the Internet of Things (IoT), Unmanned Aerial Vehicles (UAVs), blockchain, Artificial Intelligence (AI), and 5G, among others, are explored to help mitigate the impact of COVID-19 outbreak.
References
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Journal ArticleDOI
Enteric involvement of coronaviruses: is faecal-oral transmission of SARS-CoV-2 possible?
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Liver injury during highly pathogenic human coronavirus infections.
TL;DR: The characteristics and mechanism of liver injury caused by SARS‐ CoV, MERS‐CoV as well as SARS-CoV‐2 infection were summarized, which may provide help for further studies on the liver injury of COVID‐19.
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Tocilizumab in Hospitalized Patients with Severe Covid-19 Pneumonia.
Ivan O. Rosas,Norbert Bräu,Norbert Bräu,Michael F. Waters,Ronaldo C. Go,Bradley D Hunter,Sanjay Bhagani,Daniel Skiest,Mariam Aziz,Nichola Cooper,Ivor S. Douglas,Sinisa Savic,Taryn Youngstein,Lorenzo Del Sorbo,Antonio Cubillo Gracian,David J. De La Zerda,Andrew Ustianowski,Min Bao,Sophie Dimonaco,Emily Graham,Balpreet Matharu,Helen Spotswood,Larry Tsai,Atul Malhotra +23 more
TL;DR: In this paper, a randomized trial involving hospitalized patients with severe Covid-19 pneumonia, the use of tocilizumab did not result in significantly better clinical status or lower mortality than placebo at 28 days.
Journal ArticleDOI
Consensus guidelines for managing the airway in patients with COVID-19: Guidelines from the Difficult Airway Society, the Association of Anaesthetists the Intensive Care Society, the Faculty of Intensive Care Medicine and the Royal College of Anaesthetists.
TL;DR: In this paper, a consensus statement has been brought together at short notice to advise on airway management for patients with COVID-19, drawing on published literature and immediately available information from clinicians and experts.
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Neuropathological Features of Covid-19.
Isaac H. Solomon,Erica Normandin,Shamik Bhattacharyya,Shibani S. Mukerji,Kiana Keller,Ahya S. Ali,Gordon Adams,Jason L. Hornick,Robert F. Padera,Pardis C. Sabeti +9 more
TL;DR: brains of patients who died 0 to 32 days after the onset of symptoms of SARS-CoV-2 infection showed hypoxic–ischemic changes but no encephali...
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