Journal ArticleDOI
Global Cancer Incidence and Mortality Rates and Trends—An Update
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TLDR
Applied cancer control measures are needed to reduce rates in HICs and arrest the growing burden in LMICs, as well as for lung, colorectal, breast, and prostate cancer, although some low- and middle-income countries (LMIC) now count among those with the highest rates.Abstract:
There are limited published data on recent cancer incidence and mortality trends worldwide. We used the International Agency for Research on Cancer's CANCERMondial clearinghouse to present age-standardized cancer incidence and death rates for 2003-2007. We also present trends in incidence through 2007 and mortality through 2012 for select countries from five continents. High-income countries (HIC) continue to have the highest incidence rates for all sites, as well as for lung, colorectal, breast, and prostate cancer, although some low- and middle-income countries (LMIC) now count among those with the highest rates. Mortality rates from these cancers are declining in many HICs while they are increasing in LMICs. LMICs have the highest rates of stomach, liver, esophageal, and cervical cancer. Although rates remain high in HICs, they are plateauing or decreasing for the most common cancers due to decreases in known risk factors, screening and early detection, and improved treatment (mortality only). In contrast, rates in several LMICs are increasing for these cancers due to increases in smoking, excess body weight, and physical inactivity. LMICs also have a disproportionate burden of infection-related cancers. Applied cancer control measures are needed to reduce rates in HICs and arrest the growing burden in LMICs.read more
Citations
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Personalized treatment in advanced ALK-positive non-small cell lung cancer: from bench to clinical practice
Antonio Passaro,Chiara Lazzari,Niki Karachaliou,Gianluca Spitaleri,Alessia Pochesci,Chiara Catania,Rafael Rosell,Filippo de Marinis +7 more
TL;DR: The current knowledge regarding ALK-positive NSCLC, focusing on the biology of the disease and the available therapeutic options are discussed.
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Melissa Gruner,Angélique Denis,Claude Masliah,Morgane Amil,E Metivier-Cesbron,Dominique Luet,Medhi Kaasis,Emmanuel Coron,Marc Le Rhun,Stéphane Lecleire,Michel Antonietti,Jean-Louis Legoux,Laurent Lefrou,Pascal Renkes,Anne-Laure Tarreirias,Philippe Balian,P. Rey,B. Prost,Christophe Cellier,Gabriel Rahmi,Elia Samaha,Serge Fratte,Béatrice Guerrier,Verena Landel,Sandrine Touzet,Thierry Ponchon,Mathieu Pioche +26 more
TL;DR: As previously demonstrated in expert centres, NBI is more specific than Lugol in current gastroenterology practice for the detection of early SCC but combined approaches with both NBI and lugol could improve the Detection of squamous neoplasia.
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The Bacterial Microbiota of Gastrointestinal Cancers: Role in Cancer Pathogenesis and Therapeutic Perspectives.
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