Journal ArticleDOI
Global Cancer Incidence and Mortality Rates and Trends—An Update
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TLDR
Applied cancer control measures are needed to reduce rates in HICs and arrest the growing burden in LMICs, as well as for lung, colorectal, breast, and prostate cancer, although some low- and middle-income countries (LMIC) now count among those with the highest rates.Abstract:
There are limited published data on recent cancer incidence and mortality trends worldwide. We used the International Agency for Research on Cancer's CANCERMondial clearinghouse to present age-standardized cancer incidence and death rates for 2003-2007. We also present trends in incidence through 2007 and mortality through 2012 for select countries from five continents. High-income countries (HIC) continue to have the highest incidence rates for all sites, as well as for lung, colorectal, breast, and prostate cancer, although some low- and middle-income countries (LMIC) now count among those with the highest rates. Mortality rates from these cancers are declining in many HICs while they are increasing in LMICs. LMICs have the highest rates of stomach, liver, esophageal, and cervical cancer. Although rates remain high in HICs, they are plateauing or decreasing for the most common cancers due to decreases in known risk factors, screening and early detection, and improved treatment (mortality only). In contrast, rates in several LMICs are increasing for these cancers due to increases in smoking, excess body weight, and physical inactivity. LMICs also have a disproportionate burden of infection-related cancers. Applied cancer control measures are needed to reduce rates in HICs and arrest the growing burden in LMICs.read more
Citations
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Cáncer: magnitud del problema en el mundo y en Uruguay, aspectos epidemiológicos
Enrique Barrios,Mariela Garau +1 more
TL;DR: The epidemiological situation of the four most frequent cancers is analysed in Uruguay as they account for almost half of the total (female breast, prostate, lung and colo-rectum), and Uruguay shows a sustained decline in age- standardized mortality rates for all sites combined during the last two decades.
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Oncogenic targets Mmp7, S100a9, Nppb and Aldh1a3 from transcriptome profiling of FAP and Pirc adenomas are downregulated in response to tumor suppression by Clotam.
Furkan U. Ertem,Furkan U. Ertem,Wenqian Zhang,Kyle Chang,Wan Mohaiza Dashwood,Praveen Rajendran,Deqiang Sun,Ala Abudayyeh,Eduardo Vilar,Maen Abdelrahim,Maen Abdelrahim,Roderick H. Dashwood +11 more
TL;DR: In this article, the authors performed transcriptome profiling of colorectal adenomas from FAP patients and the polyposis in rat colon (Pirc) preclinical model, and prioritized molecular targets for prevention studies in vivo.
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Expression and significance of miR-24 and miR-101 in patients with advanced gastric cancer.
Xuetao Dong,Yandi Liu +1 more
TL;DR: MiR-24 and miR-101 may promote the occurrence, development, infiltration and metastasis of gastric cancer, and can be indicators for the prognosis of patients with Gastric cancer.
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Osteoporosis and fracture after gastrectomy for stomach cancer: A nationwide claims study.
TL;DR: In this article, the authors evaluated the incidence and risk factors of osteoporosis and fracture after gastrectomy for stomach cancer using a nationwide claims database in South Korea, and found that older age (hazard ratio [HR] 1.88; 95% confidence interval [CI]1.79-1.33] was significantly associated with fractures.
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Screening for Cervical Cancer.
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