Journal ArticleDOI
Global Cancer Incidence and Mortality Rates and Trends—An Update
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TLDR
Applied cancer control measures are needed to reduce rates in HICs and arrest the growing burden in LMICs, as well as for lung, colorectal, breast, and prostate cancer, although some low- and middle-income countries (LMIC) now count among those with the highest rates.Abstract:
There are limited published data on recent cancer incidence and mortality trends worldwide. We used the International Agency for Research on Cancer's CANCERMondial clearinghouse to present age-standardized cancer incidence and death rates for 2003-2007. We also present trends in incidence through 2007 and mortality through 2012 for select countries from five continents. High-income countries (HIC) continue to have the highest incidence rates for all sites, as well as for lung, colorectal, breast, and prostate cancer, although some low- and middle-income countries (LMIC) now count among those with the highest rates. Mortality rates from these cancers are declining in many HICs while they are increasing in LMICs. LMICs have the highest rates of stomach, liver, esophageal, and cervical cancer. Although rates remain high in HICs, they are plateauing or decreasing for the most common cancers due to decreases in known risk factors, screening and early detection, and improved treatment (mortality only). In contrast, rates in several LMICs are increasing for these cancers due to increases in smoking, excess body weight, and physical inactivity. LMICs also have a disproportionate burden of infection-related cancers. Applied cancer control measures are needed to reduce rates in HICs and arrest the growing burden in LMICs.read more
Citations
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Breast Cancer and the Other Non-Coding RNAs
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Amir Bagheri,Seyed Mostafa Nachvak,Mansour Rezaei,Mozhgan Moravridzade,Mahmoudreza Moradi,Michael L. Nelson +5 more
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Proceedings ArticleDOI
A multi-objective approach for calibration and detection of cervical cells nuclei
Paulo H. C. Oliveira,Gladston Moreira,Daniela Ushizima,Cláudia Martins Carneiro,Fátima N. S. de Medeiros,Flávio H. D. Araújo,Romuere R. V. Silva,Andrea Gomes Campos Bianchi +7 more
TL;DR: An algorithm combining clustering and genetic algorithms to detect image regions with high diagnostic value and a new nuclear targeting approach using heuristics associated with a multi-objective genetic algorithm are introduced.
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Germline INDELs and CNVs in a cohort of colorectal cancer patients: their characteristics, associations with relapse-free survival time, and potential time-varying effects on the risk of relapse.
Salem Werdyani,Yajun Yu,Georgia Skardasi,Jingxiong Xu,Konstantin Shestopaloff,Wei Xu,Elizabeth Dicks,Jane Green,Patrick S. Parfrey,Yildiz E. Yilmaz,Sevtap Savas +10 more
TL;DR: This is one of the first genome‐wide analyses that identified the germline INDEL/CNV profiles in colorectal cancer patients and identified germline variants that can potentially be early‐relapse markers in colordant cancer patients.
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Clinical Investigation of the Efficacy and Safety of Anlotinib with Immunotherapy in Advanced Non-Small Cell Lung Cancer as Third-Line Therapy: A Retrospective Study.
TL;DR: The clinical effectiveness of anlotinib combined with immunotherapy in advanced non-small cell lung cancer as third-line therapy was demonstrated and the main adverse events were tolerated.
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