Global cancer statistics, 2012
Lindsey A. Torre,Freddie Bray,Rebecca L. Siegel,Jacques Ferlay,Joannie Lortet-Tieulent,Ahmedin Jemal +5 more
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TLDR
A substantial portion of cancer cases and deaths could be prevented by broadly applying effective prevention measures, such as tobacco control, vaccination, and the use of early detection tests.Abstract:
Cancer constitutes an enormous burden on society in more and less economically developed countries alike. The occurrence of cancer is increasing because of the growth and aging of the population, as well as an increasing prevalence of established risk factors such as smoking, overweight, physical inactivity, and changing reproductive patterns associated with urbanization and economic development. Based on GLOBOCAN estimates, about 14.1 million new cancer cases and 8.2 million deaths occurred in 2012 worldwide. Over the years, the burden has shifted to less developed countries, which currently account for about 57% of cases and 65% of cancer deaths worldwide. Lung cancer is the leading cause of cancer death among males in both more and less developed countries, and has surpassed breast cancer as the leading cause of cancer death among females in more developed countries; breast cancer remains the leading cause of cancer death among females in less developed countries. Other leading causes of cancer death in more developed countries include colorectal cancer among males and females and prostate cancer among males. In less developed countries, liver and stomach cancer among males and cervical cancer among females are also leading causes of cancer death. Although incidence rates for all cancers combined are nearly twice as high in more developed than in less developed countries in both males and females, mortality rates are only 8% to 15% higher in more developed countries. This disparity reflects regional differences in the mix of cancers, which is affected by risk factors and detection practices, and/or the availability of treatment. Risk factors associated with the leading causes of cancer death include tobacco use (lung, colorectal, stomach, and liver cancer), overweight/obesity and physical inactivity (breast and colorectal cancer), and infection (liver, stomach, and cervical cancer). A substantial portion of cancer cases and deaths could be prevented by broadly applying effective prevention measures, such as tobacco control, vaccination, and the use of early detection tests.read more
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Fusing texture, shape and deep model-learned information at decision level for automated classification of lung nodules on chest CT
TL;DR: An algorithm for lung nodule classification that fuses the texture, shape and deep model-learned information (Fuse-TSD) at the decision level is proposed and evaluated against three approaches on the LIDC-IDRI dataset.
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Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype
Sang Cheul Oh,Sang Cheul Oh,Bo Hwa Sohn,Jae Ho Cheong,Sang Bae Kim,Jae Eun Lee,Ki Cheong Park,Sangho Lee,Jong Lyul Park,Yun Yong Park,Hyun-Sung Lee,Hee Jin Jang,Eun Sung Park,Sang Cheol Kim,Jeonghoon Heo,In Sun Chu,You Jin Jang,Young Jae Mok,Wonkyung Jung,Baek Hui Kim,Aeree Kim,Jae Yong Cho,Jae Yun Lim,Yuki Hayashi,Shumei Song,Elena Elimova,Jeannelyn S. Estralla,Jeffrey H. Lee,Manoop S. Bhutani,Yiling Lu,Wenbin Liu,Jeeyun Lee,Won Ki Kang,Sung Kim,Sung Hoon Noh,Gordon B. Mills,Seon-Young Kim,Jaffer A. Ajani,Ju Seog Lee +38 more
TL;DR: Two distinct molecular subtypes are identified, the mesenchymal subtype associated with poor survival and chemoresistance, and the epithelial phenotype associated with better survival and sensitivity to chemotherapy, by analyzing genomic and proteomic data.
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Genomic Markers in Prostate Cancer Decision Making
Vito Cucchiara,Matthew R. Cooperberg,Marc A. Dall'Era,Daniel W. Lin,Francesco Montorsi,Jack A. Schalken,Christopher P. Evans +6 more
TL;DR: The ability of genomic biomarkers to recognize men at high risk of developing PCa, discriminate clinically insignificant and aggressive tumors, and facilitate the selection of therapies in patients with advanced disease is summarized.
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Esophageal cancer statistics in China, 2011: Estimates based on 177 cancer registries.
TL;DR: Estimates of the esophageal cancer burden in China in 2011 are presented using the most recent data collected from the National Central Cancer Registry.
Journal ArticleDOI
HyperKvasir, a comprehensive multi-class image and video dataset for gastrointestinal endoscopy.
Hanna Borgli,Vajira Thambawita,Pia H. Smedsrud,Steven Alexander Hicks,Debesh Jha,Sigrun Losada Eskeland,Kristin Ranheim Randel,Konstantin Pogorelov,Mathias Lux,Duc Tien Dang Nguyen,Dag Johansen,Carsten Griwodz,Håkon Kvale Stensland,Håkon Kvale Stensland,Enrique Garcia-Ceja,Peter T. Schmidt,Hugo Lewi Hammer,Michael Riegler,Pål Halvorsen,Thomas de Lange +19 more
TL;DR: The HyperKvasir dataset is presented, the largest image and video dataset of the gastrointestinal tract available today and can play a valuable role in developing better algorithms and computer-assisted examination systems not only for gastro- and colonoscopy, but also for other fields in medicine.
References
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Jacques Ferlay,Isabelle Soerjomataram,Rajesh Dikshit,Sultan Eser,Colin Mathers,Marise Souto Rebelo,Donald Maxwell Parkin,David Forman,Freddie Bray +8 more
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Book
Cancer Incidence in Five Continents
Freddie Bray,J. Ferlay,Mathieu Laversanne,David H. Brewster,C. Gombe Mbalawa,B. Kohler,Marion Piñeros,Eva Steliarova-Foucher,Rajaraman Swaminathan,Sebastien Antoni,Isabelle Soerjomataram,David Forman +11 more
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Journal ArticleDOI
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Denise R. Aberle,Amanda M. Adams,Christine D. Berg,William C. Black,Jonathan D. Clapp,Richard M. Fagerstrom,Ilana F. Gareen,Constantine Gatsonis,Pamela M. Marcus,JoRean D. Sicks +9 more
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