Guideline of Prevention and Treatment for Chronic Hepatitis B (2015 Update).
Jinlin Hou,Guiqiang Wang,Fu-Sheng Wang,Jun Cheng,Hong Ren,Hui Zhuang,Jian Sun,Lanjuan Li,Jie Li,Qinghua Meng,Jingmin Zhao,Zhongping Duan,Jidong Jia,Hong Tang,Jifang Sheng,Jie Peng,Fengmin Lu,Qing Xie,Lai Wei +18 more
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Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, China; Department of Infectiously Diseases, Center for Liver Diseases, Peking University First Hospital, Beijing; The Institute of Translational Hepatology, 302 Hospital of PLA, P Beijing, China.Abstract:
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, China; Department of Infectious Diseases, Center for Liver Diseases, Peking University First Hospital, Beijing, China; The Institute of Translational Hepatology, 302 Hospital of PLA, Peking University, Beijing, China; Center of Liver Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China; Institute for Viral Hepatitis, the Key Laboratory of Molecular Biology for Infectious Diseases, the second Affiliated Hospital of Chongqing Medical University, Chongqing, China; Department of Microbiology of Peking University Health Science Center, Beijing, China; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China; Serious Illness Medicine Inpatient Area, Beijing Youan Hospital, Capital Medical University, Beijing, China; Department of Pathology, 302 Hospital of PLA, Peking University, Beijing, China; Artificial Liver Center, Beijing Youan Hospital, Capital Medical University, Beijing, China; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China; Center of Infectious Diseases, West China Hospital of Sichuan University, Division of Infectious Diseases, State Key Laboratory of Biotherapy, Sichuan University, Chengdu, China; Department of Infectious Diseases, Shanghai Jiao Tong University School of Medicine Affiliated Ruijin Hospital, Shanghai, China; Hepatology Institute, Peking University People’s Hospital, Beijing, Chinaread more
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Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission
Graham S Cooke,Isabelle Andrieux-Meyer,Tanya L. Applegate,Rifat Atun,Jessica R Burry,Hugo Cheinquer,G.M. Dusheiko,Jordan J. Feld,Charles Gore,Max Griswold,Saeed Hamid,Margaret Hellard,Jinlin Hou,J. Howell,Jidong Jia,Natalia Kravchenko,Jeffrey V. Lazarus,Maud Lemoine,Olufunmilayo A. Lesi,Liudmyla Maistat,Brian J. McMahon,Homie Razavi,Teri Roberts,Bryony Simmons,Mark W. Sonderup,C Wendy Spearman,Bridie E Taylor,David L. Thomas,Imam Waked,John W. Ward,Stefan Wiktor,Ayman Abdo,Rakesh Aggarwal,Alessio Aghemo,Bandar Al-Judaibi,Mamun Al Mahtab,Arshad Altaf,Zyaad Ameen,Tarik Asselah,Oidov Baatarkkhuu,Ella Barber,Eleanor Barnes,Pascale Boulet,Louise Burrows,Maia Butsashvili,Erica Chan,Chelsea Chow,Ben Cowie,Chris Cunningham,Alexandre de Araujo,Graciela Diap,G.J. Dore,Joseph Doyle,Manal Elsayed,Emmanuel Fajardo,Edward Gane,Aneley Getahun,David J. Goldberg,Tiffany Got,Matthew Hickman,Andrew F. Hill,Sharon J. Hutchinson,Christopher R. Jones,Saleem Kamili,Amreen Khan,Alice Lee,Tin Yan Lee,Jioiji Malani,Tammy Meyers Morris,Shevanthi Nayagam,Richard Njouom,Ponsiano Ocama,Alisa Pedrana,Rosanna W. Peeling,Amulya Reddy,Jilian A. Sacks,Shiv Kumar Sarin,Yusuke Shimakawa,Marcela Silva,Pavlo Skala,Simon D. Taylor-Robinson,Alexander J. Thompson,Mark Thursz,Alfred Tonganibeia,Jack Wallace,James Ward,Fernando Herz Wolff,Peter Vickerman,Johnny Yau +88 more
TL;DR: Key recommendations include a greater focus on national progress towards elimination with support given, if necessary, through innovative financing measures to ensure elimination programmes are fully funded by 2020.
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Camrelizumab in patients with previously treated advanced hepatocellular carcinoma: a multicentre, open-label, parallel-group, randomised, phase 2 trial
Shukui Qin,Zhenggang Ren,Zhiqiang Meng,Zhendong Chen,Xiaoli Chai,Jianping Xiong,Yuxian Bai,Lin Yang,Hong Zhu,Weijia Fang,Xiaoyan Lin,Xiaoming Chen,Enxiao Li,Linna Wang,Chunxia Chen,Jianjun Zou +15 more
TL;DR: Camrelizumab showed antitumour activity in pretreated Chinese patients with advanced hepatocellular carcinoma, with manageable toxicities, and might represent a new treatment option for these patients.
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Therapeutic strategies for hepatitis B virus infection: towards a cure
TL;DR: Advances in hepatitis B therapies and challenges for their development are reviewed, including antiviral and immune-boosting strategies that could be part of combination strategies to achieve functional cure.
Journal ArticleDOI
Liver diseases in the Asia-Pacific region: a Lancet Gastroenterology & Hepatology Commission.
Shiv Kumar Sarin,Manoj Kumar,Mohammed Eslam,Jacob George,Mamun Al Mahtab,Sheikh Mohammad Fazle Akbar,Jidong Jia,Qiuju Tian,Rakesh Aggarwal,David H. Muljono,Masao Omata,Yoshihiko Ooka,Kwang Hyub Han,Hye Won Lee,Wasim Jafri,Amna Subhan Butt,Chern H. Chong,Seng Gee Lim,Seng Gee Lim,R.F. Pwu,Ding-Shinn Chen,Ding-Shinn Chen +21 more
TL;DR: Efforts to eliminate viral hepatitis as a public health threat, together with the rapid increase in per-capita alcohol consumption in countries and the epidemic of obesity, are expected to change the spectrum of liver diseases in the Asia-Pacific region in the near future.
Journal ArticleDOI
Global liver disease burdens and research trends: Analysis from a Chinese perspective.
Jia Xiao,Fei Wang,Nai-Kei Wong,Jinhan He,Rui Zhang,Ruijuan Sun,Yanying Xu,Yingxia Liu,Wei Li,Kazuo Koike,Weiling He,Hong You,Yinglei Miao,Xiaowei Liu,Mingming Meng,Bin Gao,Hua Wang,Cui Li +17 more
TL;DR: Wang et al. as mentioned in this paper provided stimulating glimpses into the evolving liver disease epidemiology, institutional research profiles, funding landscape, and drug development trends in China, with an attempt to compare her status and achievements with those of the United States, European countries, and Japan.
References
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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
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TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.
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A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C
Chun-Tao Wai,Joel K. Greenson,Robert J. Fontana,John D. Kalbfleisch,Jorge A. Marrero,Hari S. Conjeevaram,Anna S.F. Lok +6 more
TL;DR: It is shown that a simple index using readily available laboratory results can identify CHC patients with significant fibrosis and cirrhosis with a high degree of accuracy and may decrease the need for staging liver biopsy specimens among patients with CHC.
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An algorithm for the grading of activity in chronic hepatitis C
Pierre Bedossa,Thierry Poynard +1 more
TL;DR: A simple algorithm that generates a single activity score based on basic pathological features in chronic hepatitis C is proposed and tested, showing its accuracy is as high as that obtained using a statistical approach.
Journal ArticleDOI
Chronic hepatitis B: Update 2009
Anna S.F. Lok,Brian J. McMahon +1 more
TL;DR: The 2009 update of the American Association for the Study of Liver Diseases (AASLD) Practice Guidelines for Management of Chronic Hepatitis B is now posted online at www.aasld.org, and the recommendation for first-line oral antiviral medications has been changed to tenofovir or entecavir, and adefovir has been moved to second-line Oral antiviral medication.
Journal ArticleDOI
EASL Recommendations on Treatment of Hepatitis C
Jean-Michel Pawlotsky,Alessio Aghemo,Geoffrey Dusheiko,Xavier Forns,Massimo Puoti,Christophe Sarrazin +5 more
TL;DR: The optimal management of patients with acute and chronic HCV infections in 2018 and onwards is described, as well as developments in diagnostic procedures and improvements in therapy and prevention.
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