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Journal ArticleDOI

Insect vitellogenin/lipophorin receptors: molecular structures, role in oogenesis, and regulatory mechanisms.

Muhammad Tufail, +1 more
- 01 Feb 2009 - 
- Vol. 55, Iss: 2, pp 87-103
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TLDR
The expression studies clearly demonstrate that insect VgRs are ovary-bound receptors of the LDLR family as compared to LpRs, which are transcribed in a wide range of tissues including ovary, fat body, midgut, brain, testis, Malpighian tubules, and muscles.
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This article is published in Journal of Insect Physiology.The article was published on 2009-02-01. It has received 206 citations till now. The article focuses on the topics: Domain of unknown function.

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Citations
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Journal ArticleDOI

Insect Fat Body: Energy, Metabolism, and Regulation

TL;DR: This review focuses on energy storage and release in insects and summarizes current understanding of the mechanisms underlying these processes in insects.
Journal ArticleDOI

Molecular traces of alternative social organization in a termite genome

TL;DR: The genome and stage-specific transcriptomes of the dampwood termite Zootermopsis nevadensis (Blattodea) are sequence and similarities in the number and expression of genes related to caste determination mechanisms support a hypothesized epigenetic regulation of caste differentiation.
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Targeted delivery of CRISPR-Cas9 ribonucleoprotein into arthropod ovaries for heritable germline gene editing

TL;DR: A peptide (P2C) is identified that mediates transduction of Cas9 RNP from the female hemolymph to the developing mosquito oocytes, resulting in heritable gene editing of the offspring with efficiency as high as 0.3 mutants per injected mosquito.
Journal ArticleDOI

Eat to reproduce: a key role for the insulin signaling pathway in adult insects.

TL;DR: The current review will present an overview of the regulatory role of the ISP in female insect reproduction and its interaction with other pathways involving nutrients, lipophilic hormones and neuropeptides.
References
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Journal ArticleDOI

Clustal w: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

TL;DR: The sensitivity of the commonly used progressive multiple sequence alignment method has been greatly improved and modifications are incorporated into a new program, CLUSTAL W, which is freely available.
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A receptor-mediated pathway for cholesterol homeostasis.

TL;DR: The approach was to apply the techniques of cell culture to unravel the postulated regulatory defect in FH, which led to the discovery of a cell surface receptor for a plasma cholesterol transport protein called low density lipoprotein (LDL) and to the elucidation of the mechanism by which this receptor mediates feedback control of cholesterol synthesis.
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Sequence and structure-based prediction of eukaryotic protein phosphorylation sites.

TL;DR: An artificial neural network method is presented that predicts phosphorylation sites in independent sequences with a sensitivity in the range from 69 % to 96 % and predicts novel phosphorylated sites in the p300/CBP protein that may regulate interaction with transcription factors and histone acetyltransferase activity.
Journal ArticleDOI

Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System

TL;DR: This data indicates that intracellular routes in the response of the immune system to EMT are regulated by Tournaisian reprograming, a type of ‘spatially aggregating’ behaviour.
Journal ArticleDOI

Binding and Degradation of Low Density Lipoproteins by Cultured Human Fibroblasts COMPARISON OF CELLS FROM A NORMAL SUBJECT AND FROM A PATIENT WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA

TL;DR: It is raised that a prerequisite for the regulation of cholestero-genesis in cultured fibroblasts is the initial binding of low density lipoproteins to the high affinity surface receptor sites and that a defect in this process represents the primary genetic abnormality in the disorder familial hypercholesterolemia.
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