Journal ArticleDOI
Molecularly organic/inorganic hybrid hollow mesoporous organosilica nanocapsules with tumor-specific biodegradability and enhanced chemotherapeutic functionality.
TLDR
This research provides a paradigm that framework organic-inorganic hybridization can endow the inorganic nanocarrier with unique biological effects suitable for biomedical application, benefiting the development of novel nanosystems with the unique bio-functionality and performance.About:
This article is published in Biomaterials.The article was published on 2017-05-01. It has received 166 citations till now. The article focuses on the topics: Mesoporous organosilica & Mesoporous silica.read more
Citations
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High‐efficient surface tailoring via reverse atom transfer radical polymerization and reversible addition‐fragmentation chain‐transfer polymerization in an aqueous system initiated by a monocenter redox pair
Haipeng Yang,Shuipi Cai,Yu Jiang,Zheng Cao,Wen Jie Ma,Fanghong Gong,Guoliang Tao,Chunlin Liu +7 more
Journal ArticleDOI
Nanotechnology-integrated ovarian cancer metastasis therapy: Insights from the metastatic mechanisms into administration routes and therapy strategies.
Yu Huang,Chaoqun Li,Xiao Zhang,Meng Zhang,Yidan Ma,Dongxu Qin,Sang-sang Tang,Weidong Fei,Jiale Qin +8 more
TL;DR: In this paper , the advantages of various administration routes of nanodrugs in metastatic ovarian cancer therapy were discussed. And the challenges and prospects of nanotherapeutics for ovarian cancer metastasis therapy were evaluated.
DissertationDOI
Hybrid Organic-Inorganic Bridged Silsesquioxane Nanoparticles for Cancer Nanomedicine
TL;DR: The performed research in this dissertation is completely based on hybrid organicinorganic bridged silsesquioxane nanomaterials, therefore comprising soft orga / ioorga part can imitate certain biorelevant structures and facilitates successful escape from the immune system for more efficient accumulation.
Journal ArticleDOI
Recent advances on nanostructured biomaterials in osteosarcoma treatment
TL;DR: In this paper , the authors summarized the research progress of nanoparticles closely related to the treatment of osteosarcoma in recent years and described the therapeutic strategies of nanophotonics.
Journal ArticleDOI
Noninvasive remote-controlled nanomedicine by using electric field stimulation for in vivo effective cancer therapy
TL;DR: The EFTDDS is demonstrated biodegradable, biocompatible, and EF remotely controllable, represents excellent inhibiting effect on tumor in vivo, and might become a promising nanomedicine platform for electrodynamic therapy (EDT) in the potential clinical applications.
References
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Journal ArticleDOI
Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts
Martin Lundqvist,Johannes Stigler,Giuliano Elia,Iseult Lynch,Tommy Cedervall,Kenneth A. Dawson +5 more
TL;DR: The long-lived (“hard”) protein corona formed from human plasma is studied for a range of nanoparticles that differ in surface properties and size and both size and surface properties were found to play a very significant role.
Journal ArticleDOI
Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers
TL;DR: This review highlights the recent research developments of a series of surface-functionalized mesoporous silica nanoparticle (MSN) materials as efficient drug delivery carriers and envision that these MSN-based systems have a great potential for a variety of drug delivery applications.
Journal ArticleDOI
Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery
TL;DR: The in vitro and in vivo biocompatibility and biotranslocation of MSNs are discussed in relation to their chemophysical properties including particle size, surface properties, shape, and structure.
Journal ArticleDOI
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
Horacio Cabral,Yu Matsumoto,Kazue Mizuno,Qixian Chen,Mami Murakami,M. Kimura,Yasuko Terada,Mitsunobu R. Kano,Kohei Miyazono,Mitsuru Uesaka,Nobuhiro Nishiyama,Kazunori Kataoka +11 more
TL;DR: It is shown that the penetration and efficacy of the larger micelles could be enhanced by using a transforming growth factor-β inhibitor to increase the permeability of the tumours.
Journal ArticleDOI
Demonstration of a spaser-based nanolaser
Mikhail A. Noginov,Guohua Zhu,A. M. Belgrave,Reuben M. Bakker,Vladimir M. Shalaev,Evgenii E. Narimanov,S Stout,S Stout,Erik Herz,Teeraporn Suteewong,Ulrich Wiesner +10 more
TL;DR: It is shown that 44-nm-diameter nanoparticles with a gold core and dye-doped silica shell allow us to completely overcome the loss of localized surface plasmons by gain and realize a spaser, and that outcoupling of surface plasmon oscillations to photonic modes at a wavelength of 531 nm makes this system the smallest nanolaser reported to date—and to the authors' knowledge the first operating at visible wavelengths.