Neurobiology of the incubation of drug craving
Charles L. Pickens,Mikko Airavaara,Florence R. M. Theberge,Sanya Fanous,Bruce T. Hope,Yavin Shaham +5 more
TLDR
Recent results that have identified important brain regions involved in the incubation of drug craving in rodents are discussed, as well as evidence for the underlying cellular mechanisms.About:
This article is published in Trends in Neurosciences.The article was published on 2011-08-01 and is currently open access. It has received 550 citations till now. The article focuses on the topics: Craving & Methamphetamine.read more
Citations
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Cocaine induces input and cell-type-specific synaptic plasticity in ventral pallidum-projecting nucleus accumbens medium spiny neurons
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GluN3-Containing NMDA Receptors in the Rat Nucleus Accumbens Core Contribute to Incubation of Cocaine Craving.
Daniel T. Christian,Michael T. Stefanik,Linda A. Bean,Jessica A. Loweth,Amanda M. Wunsch,Jonathan R. Funke,Clark A. Briggs,Joseph Lyons,Demetria Neal,Mike Milovanovic,Gary X. D'Souza,Grace E. Stutzmann,Daniel A. Nicholson,Kuei Y. Tseng,Marina E. Wolf +14 more
TL;DR: In this paper, the authors found that AMPAR plasticity is preceded by NMDAR plasticity that is essential for incubation and involves GluN3, which confers atypical properties including insensitivity to Mg2+ block and Ca2+-impermeability.
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Repeated Transcranial Direct Current Stimulation (tDCS) on Methamphetamine Craving: A Randomized, Sham-controlled Study
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Different brain oxidative and neuroinflammation status in rats during prolonged abstinence depending on their ethanol relapse-like drinking behavior: Effects of ethanol reintroduction
TL;DR: In this article , the authors used a model based on the alcohol deprivation effect (ADE) within a cohort of wild-type male Wistar rats, and two sub-populations were identified according to the alcohol relapse-like drinking behavior displayed (ADE and NO-ADE subpopulations).
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Opioid and Sucrose Craving Are Accompanied by Unique Behavioral and Affective Profiles after Extended Abstinence in Male and Female Rats
TL;DR: In this paper , the influence of the female estrous cycle on opioid self-administration in rats was examined and a sex and reinforcer-specific behavioral and affective signature of craving emerged.
References
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Matti S. Airaksinen,Mart Saarma +1 more
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