Book ChapterDOI
Nonparametric Estimation from Incomplete Observations
Edward L. Kaplan,Paul Meier +1 more
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In this article, the product-limit (PL) estimator was proposed to estimate the proportion of items in the population whose lifetimes would exceed t (in the absence of such losses), without making any assumption about the form of the function P(t).Abstract:
In lifetesting, medical follow-up, and other fields the observation of the time of occurrence of the event of interest (called a death) may be prevented for some of the items of the sample by the previous occurrence of some other event (called a loss). Losses may be either accidental or controlled, the latter resulting from a decision to terminate certain observations. In either case it is usually assumed in this paper that the lifetime (age at death) is independent of the potential loss time; in practice this assumption deserves careful scrutiny. Despite the resulting incompleteness of the data, it is desired to estimate the proportion P(t) of items in the population whose lifetimes would exceed t (in the absence of such losses), without making any assumption about the form of the function P(t). The observation for each item of a suitable initial event, marking the beginning of its lifetime, is presupposed. For random samples of size N the product-limit (PL) estimate can be defined as follows: L...read more
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Journal ArticleDOI
Influence of Diabetes Mellitus on Early and Late Outcome After Percutaneous Transluminal Coronary Angioplasty
Bernardo Stein,William S. Weintraub,Suzanne S. P. Gebhart,Caryn L. Cohen-Bernstein,Ralph Grosswald,Henry A. Liberman,John S. Douglas,Douglas C. Morris,Spencer B. King +8 more
TL;DR: Although long-term survival is acceptable, diabetics have a higher rate of infarction and a greater need for additional revascularization procedures, probably because of early restenosis and late progression of coronary disease.
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Prognostic importance of social and economic resources among medically treated patients with angiographically documented coronary artery disease.
Redford B. Williams,John C. Barefoot,Robert M. Califf,Thomas L. Haney,William B. Saunders,David B. Pryor,Mark A. Hlatky,Ilene C. Siegler,Daniel B. Mark +8 more
TL;DR: In this paper, the authors evaluate the hypothesis that diminished social and economic resources impact adversely on cardiovascular mortality in patients with coronary artery disease, and they find that low levels of economic resources identify an important high-risk group among medically treated patients, independent of important baseline invasive and noninvasive medical prognostic factors.
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A Pooled Analysis of Eastern Cooperative Oncology Group and Intergroup Trials of Adjuvant High-Dose Interferon for Melanoma
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Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial: Design and Methods
TL;DR: The ACCORD trial should document for the first time the benefits and risks of intensive glucose control, intensive blood pressure control, and the combination of fibrate and statin drugs in managing blood lipids in high-risk patients with type 2 diabetes.
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Impact of variability among surgeons on postoperative morbidity and mortality and ultimate survival.
C S McArdle,David J Hole +1 more
TL;DR: There were significant variations in patient outcome among surgeons after surgery for colorectal cancer; such differences compromise survival.
References
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Journal ArticleDOI
Survival Curve for Cancer Patients Following Treatment
Joseph Berkson,Robert P. Gage +1 more
TL;DR: A simple function, in terms of two physically meaningful parameters, has been evolved, which fits survivorship data very well and can be used to compare succinctly the mortality of two groups, different in respect of treatment, type of cancer, or other characteristics.
Journal ArticleDOI
An analysis of some failure data
TL;DR: The rationale and statistical techniques employed in the analysis of some failure data obtained from operations performed by machines and people are summarized and the agreement between theory and data is evaluated.