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Book ChapterDOI

Nonparametric Estimation from Incomplete Observations

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TLDR
In this article, the product-limit (PL) estimator was proposed to estimate the proportion of items in the population whose lifetimes would exceed t (in the absence of such losses), without making any assumption about the form of the function P(t).
Abstract
In lifetesting, medical follow-up, and other fields the observation of the time of occurrence of the event of interest (called a death) may be prevented for some of the items of the sample by the previous occurrence of some other event (called a loss). Losses may be either accidental or controlled, the latter resulting from a decision to terminate certain observations. In either case it is usually assumed in this paper that the lifetime (age at death) is independent of the potential loss time; in practice this assumption deserves careful scrutiny. Despite the resulting incompleteness of the data, it is desired to estimate the proportion P(t) of items in the population whose lifetimes would exceed t (in the absence of such losses), without making any assumption about the form of the function P(t). The observation for each item of a suitable initial event, marking the beginning of its lifetime, is presupposed. For random samples of size N the product-limit (PL) estimate can be defined as follows: L...

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Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint radiation therapy oncology group and eastern cooperative oncology group study

TL;DR: Evaluating the efficacy after neurosurgery of three new treatment options as compared with control treatment of radiotherapy alone found that age was the most important prognostic factor and a modified histologic classification of anaplastic astrocytoma versus glioblastoma provided better prognostic information than the astroicytoma grading system of Kernohan.
Journal ArticleDOI

Theory and applications of hazard plotting for censored failure data

TL;DR: Applications of the hazard plotting method are given for multiply censored data on service life of equipment, for strength data on an item with different failure modes, and for biological data multiply censored on both sides from paired comparisons.
References
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Journal ArticleDOI

Survival Curve for Cancer Patients Following Treatment

TL;DR: A simple function, in terms of two physically meaningful parameters, has been evolved, which fits survivorship data very well and can be used to compare succinctly the mortality of two groups, different in respect of treatment, type of cancer, or other characteristics.
Journal ArticleDOI

The natural duration of cancer

W. S. Lazarus-Barlow, +1 more
- 16 Aug 1924 - 
Journal ArticleDOI

An analysis of some failure data

TL;DR: The rationale and statistical techniques employed in the analysis of some failure data obtained from operations performed by machines and people are summarized and the agreement between theory and data is evaluated.
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