Book ChapterDOI
Nonparametric Estimation from Incomplete Observations
Edward L. Kaplan,Paul Meier +1 more
Reads0
Chats0
TLDR
In this article, the product-limit (PL) estimator was proposed to estimate the proportion of items in the population whose lifetimes would exceed t (in the absence of such losses), without making any assumption about the form of the function P(t).Abstract:
In lifetesting, medical follow-up, and other fields the observation of the time of occurrence of the event of interest (called a death) may be prevented for some of the items of the sample by the previous occurrence of some other event (called a loss). Losses may be either accidental or controlled, the latter resulting from a decision to terminate certain observations. In either case it is usually assumed in this paper that the lifetime (age at death) is independent of the potential loss time; in practice this assumption deserves careful scrutiny. Despite the resulting incompleteness of the data, it is desired to estimate the proportion P(t) of items in the population whose lifetimes would exceed t (in the absence of such losses), without making any assumption about the form of the function P(t). The observation for each item of a suitable initial event, marking the beginning of its lifetime, is presupposed. For random samples of size N the product-limit (PL) estimate can be defined as follows: L...read more
Citations
More filters
Journal ArticleDOI
Incidence and clinical features of trigeminal neuralgia, Rochester, Minnesota, 1945-1984.
TL;DR: An elevated relative risk associated with hypertension (both overall and among women in the cohort) is indicated and prevalence of multiple sclerosis was significantly greater among the group of 75 patients who had trigeminal neuralgia.
Journal ArticleDOI
Peripheral T-cell lymphoma unspecified (PTCL-U): a new prognostic model from a retrospective multicentric clinical study
Andrea Gallamini,Caterina Stelitano,R Calvi,Monica Bellei,Daniele Mattei,Umberto Vitolo,Fortunato Morabito,Maurizio Martelli,Ercole Brusamolino,Emilio Iannitto,Francesco Zaja,Sergio Cortelazzo,Luigi Rigacci,Liliana Devizzi,Giuseppe Todeschini,Gino Santini,Maura Brugiatelli,Massimo Federico +17 more
TL;DR: To assess the prognosis of peripheral T-cell lymphoma unspecified, retrospectively analyzed 385 cases fulfilling the criteria defined by the World Health Organization classification and constructed a new prognostic model that singled out 4 groups at different risk.
Journal ArticleDOI
Cancer Incidence After Retinoblastoma: Radiation Dose and Sarcoma Risk
F. L. Wong,John D. Boice,David H. Abramson,Robert E. Tarone,Ruth A. Kleinerman,Marilyn Stovall,M. B. Goldman,Johanna M. Seddon,Nancy J. Tarbell,Joseph F. Fraumeni,FrederickP. Li +10 more
TL;DR: In this paper, the authors examined the long-term risk of new primary cancers in survivors of childhood retinoblastoma and quantify the role of radiotherapy in sarcoma development.
Journal ArticleDOI
Survival of Medicare Patients After Enrollment in Hospice Programs
TL;DR: Survival varied substantially according to diagnosis, even after adjustment for age and co-existing conditions, and it was longest for those with chronic lung disease, those with dementia, and those with breast cancer, while patients at for-profit, larger, outpatient, or newer hospices lived longer after enrollment than those in other types of hospice programs.
Journal ArticleDOI
Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer.
M. J. O'Connell,James A. Mailliard,M J Kahn,John S. Macdonald,Daniel G. Haller,Robert J. Mayer,Harry S. Wieand +6 more
TL;DR: Results indicate that intensive-course 5FU plus low-dose leucovorin is effective in preventing tumor relapse and improving survival in patients with high-risk colon cancer.
References
More filters
Journal ArticleDOI
Survival Curve for Cancer Patients Following Treatment
Joseph Berkson,Robert P. Gage +1 more
TL;DR: A simple function, in terms of two physically meaningful parameters, has been evolved, which fits survivorship data very well and can be used to compare succinctly the mortality of two groups, different in respect of treatment, type of cancer, or other characteristics.
Journal ArticleDOI
An analysis of some failure data
TL;DR: The rationale and statistical techniques employed in the analysis of some failure data obtained from operations performed by machines and people are summarized and the agreement between theory and data is evaluated.