The burden of inflammatory bowel disease in Europe.
TLDR
The aim of this review is to describe the burden of IBD in Europe by discussing the latest epidemiological data, the disease course and risk for surgery and hospitalization, mortality and cancer risks, as well as the economic aspects, patients' disability and work impairment.About:
This article is published in Journal of Crohn's and Colitis.The article was published on 2013-05-01 and is currently open access. It has received 787 citations till now. The article focuses on the topics: Disease management (health) & Quality of life (healthcare).read more
Citations
More filters
Journal ArticleDOI
Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies
Siew C. Ng,Hai Yun Shi,Hai Yun Shi,Nima Hamidi,Fox E. Underwood,Whitney Tang,Eric I Benchimol,Eric I Benchimol,Remo Panaccione,Subrata Ghosh,Justin C.Y. Wu,Francis K.L. Chan,Joseph J.Y. Sung,Gilaad G. Kaplan +13 more
TL;DR: The changing incidence and prevalence of inflammatory bowel disease around the world has become a global disease with accelerating incidence in newly industrialised countries whose societies have become more westernised and burden remains high as prevalence surpasses 0·3%.
Journal ArticleDOI
The global burden of IBD: from 2015 to 2025
TL;DR: The goal of this article is to establish the current epidemiology of IBD in the Western world, contrast it with the increase in IBD on health-care systems in newly industrialized countries and forecast the global effects of I BD in 2025.
Journal ArticleDOI
Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extra-intestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders.
Fernando Magro,Paolo Gionchetti,Rami Eliakim,Sandro Ardizzone,Alessandro Armuzzi,Manuel Barreiro-de Acosta,Johan Burisch,Krisztina Gecse,Ailsa Hart,Pieter Hindryckx,Cord Langner,Jimmy K. Limdi,Gianluca Pellino,Edyta Zagórowicz,Tim Raine,Marcus Harbord,Florian Rieder +16 more
TL;DR: This research presents a meta-analyses of Gastroenterology and Hepatology at the cellular and molecular level, which shows clear trends in the development of immune-oncology-metabolical pathways towards “clinically checkpoints”.
Journal ArticleDOI
The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017
Sudabeh Alatab,Sadaf G. Sepanlou,Kevin Ikuta,Homayoon Vahedi,Catherine Bisignano,Saeid Safiri,Anahita Sadeghi,Molly R Nixon,Amir Abdoli,Hassan Abolhassani,Vahid Alipour,Majid A Almadi,Amir Almasi-Hashiani,Amir Anushiravani,Jalal Arabloo,Suleman Atique,Ashish Awasthi,Alaa Badawi,Atif Amin Baig,Neeraj Bhala,Ali Bijani,Antonio Biondi,Antonio Maria Borzì,Kristin E Burke,Félix Carvalho,Ahmad Daryani,Manisha Dubey,Aziz Eftekhari,Eduarda Fernandes,João C. Fernandes,Florian Fischer,Arvin Haj-Mirzaian,Arya Haj-Mirzaian,Amir Hasanzadeh,Maryam Hashemian,Simon I. Hay,Chi L Hoang,Mowafa Househ,Olayinka Stephen Ilesanmi,Nader Jafari Balalami,Spencer L. James,Andre Pascal Kengne,Masoud M Malekzadeh,Shahin Merat,Tuomo J. Meretoja,Tomislav Mestrovic,Erkin M. Mirrakhimov,Hamid Reza Mirzaei,Karzan Abdulmuhsin Mohammad,Ali H. Mokdad,Lorenzo Monasta,Ionut Negoi,Trang Huyen Nguyen,Cuong Tat Nguyen,Akram Pourshams,Hossein Poustchi,Mohammad Rabiee,Navid Rabiee,Kiana Ramezanzadeh,David Laith Rawaf,Salman Rawaf,Nima Rezaei,Stephen R. Robinson,Luca Ronfani,Sonia Saxena,Masood Sepehrimanesh,Masood Ali Shaikh,Zeinab Sharafi,Mehdi Sharif,Soraya Siabani,Ali Reza Sima,Jasvinder A. Singh,Amin Soheili,Rasoul Sotoudehmanesh,Hafiz Ansar Rasul Suleria,Berhe Etsay Tesfay,Bach Xuan Tran,Derrick Tsoi,Marco Vacante,Adam Belay Wondmieneh,Afshin Zarghi,Zhi-Jiang Zhang,Mae Dirac,Reza Malekzadeh,Mohsen Naghavi +84 more
TL;DR: The prevalence of IBD increased substantially in many regions from 1990 to 2017, which might pose a substantial social and economic burden on governments and health systems in the coming years.
Journal ArticleDOI
How informative is the mouse for human gut microbiota research
Thi Loan Anh Nguyen,Thi Loan Anh Nguyen,Sara Vieira-Silva,Sara Vieira-Silva,Adrian Liston,Jeroen Raes,Jeroen Raes +6 more
TL;DR: The intrinsic similarities and differences that exist between the two systems are discussed, and the human and murine core gut microbiota are compared based on a meta-analysis of currently available datasets.
References
More filters
Journal ArticleDOI
The outcome of childhood Haemophilus influenzae meningitis. A population based study.
TL;DR: To determine the morbidity and mortality from childhood Haemophilus influenzae type b (Hib) meningitis in a well defined population, a large number of cases are diagnosed with Hib.
Journal ArticleDOI
Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review
Natalie A. Molodecky,Ing Shian Soon,Doreen M. Rabi,William A. Ghali,Mollie Ferris,Greg W. Chernoff,Eric I Benchimol,Eric I Benchimol,Remo Panaccione,Subrata Ghosh,Herman W. Barkema,Gilaad G. Kaplan +11 more
TL;DR: Although there are few epidemiologic data from developing countries, the incidence and prevalence of IBD are increasing with time and in different regions around the world, indicating its emergence as a global disease.
Journal ArticleDOI
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins,Stephan Ripke,Rinse K. Weersma,Richard H. Duerr,Dermot P.B. McGovern,Ken Y. Hui,James Lee,L. Philip Schumm,Yashoda Sharma,Carl A. Anderson,Jonah Essers,Mitja Mitrovic,Kaida Ning,Isabelle Cleynen,Emilie Theatre,Sarah L. Spain,Soumya Raychaudhuri,Philippe Goyette,Zhi Wei,Clara Abraham,Jean-Paul Achkar,Tariq Ahmad,Leila Amininejad,Ashwin N. Ananthakrishnan,Vibeke Andersen,Jane M. Andrews,Leonard Baidoo,Tobias Balschun,Peter A. Bampton,Alain Bitton,Gabrielle Boucher,Stephan Brand,Carsten Büning,Ariella Cohain,Sven Cichon,Mauro D'Amato,Dirk De Jong,Kathy L Devaney,Marla Dubinsky,Cathryn Edwards,David Ellinghaus,Lynnette R. Ferguson,Denis Franchimont,Karin Fransen,Richard B. Gearry,Michel Georges,Christian Gieger,Jürgen Glas,Talin Haritunians,Ailsa Hart,Christopher J. Hawkey,Matija Hedl,Xinli Hu,Tom H. Karlsen,Limas Kupčinskas,Subra Kugathasan,Anna Latiano,Debby Laukens,Ian C. Lawrance,Charlie W. Lees,Edouard Louis,Gillian Mahy,John C. Mansfield,Angharad R. Morgan,Craig Mowat,William G. Newman,Orazio Palmieri,Cyriel Y. Ponsioen,Uroš Potočnik,Natalie J. Prescott,Miguel Regueiro,Jerome I. Rotter,Richard K Russell,Jeremy D. Sanderson,Miquel Sans,Jack Satsangi,Stefan Schreiber,Lisa A. Simms,Jurgita Sventoraityte,Stephan R. Targan,Kent D. Taylor,Mark Tremelling,Hein W. Verspaget,Martine De Vos,Cisca Wijmenga,David C. Wilson,Juliane Winkelmann,Ramnik J. Xavier,Sebastian Zeissig,Bin Zhang,Clarence K. Zhang,Hongyu Zhao,Mark S. Silverberg,Vito Annese,Hakon Hakonarson,Steven R. Brant,Graham L. Radford-Smith,Christopher G. Mathew,John D. Rioux,Eric E. Schadt,Mark J. Daly,Andre Franke,Miles Parkes,Severine Vermeire,Jeffrey C. Barrett,Judy H. Cho +105 more
TL;DR: A meta-analysis of Crohn’s disease and ulcerative colitis genome-wide association scans is undertaken, followed by extensive validation of significant findings, with a combined total of more than 75,000 cases and controls.
Journal ArticleDOI
Infliximab for induction and maintenance therapy for ulcerative colitis.
Paul Rutgeerts,William J. Sandborn,Brian G. Feagan,Walter Reinisch,Allan Olson,Jewel Johanns,Suzanne Travers,Daniel Rachmilewitz,Stephen B. Hanauer,Gary R. Lichtenstein,Willem J.S. de Villiers,Daniel H. Present,Bruce E. Sands,Jean-Frederic Colombel +13 more
TL;DR: Patients with moderate-to-severe active ulcerative colitis treated with infliximab at weeks 0, 2, and 6 and every eight weeks thereafter were more likely to have a clinical response at weeks 8, 30, and 54 than were those receiving placebo.
Journal ArticleDOI
Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences
TL;DR: Differences in incidence across age, time, and geographic region suggest that environmental factors significantly modify the expression of Crohn's disease and ulcerative colitis.
Related Papers (5)
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins,Stephan Ripke,Rinse K. Weersma,Richard H. Duerr,Dermot P.B. McGovern,Ken Y. Hui,James Lee,L. Philip Schumm,Yashoda Sharma,Carl A. Anderson,Jonah Essers,Mitja Mitrovic,Kaida Ning,Isabelle Cleynen,Emilie Theatre,Sarah L. Spain,Soumya Raychaudhuri,Philippe Goyette,Zhi Wei,Clara Abraham,Jean-Paul Achkar,Tariq Ahmad,Leila Amininejad,Ashwin N. Ananthakrishnan,Vibeke Andersen,Jane M. Andrews,Leonard Baidoo,Tobias Balschun,Peter A. Bampton,Alain Bitton,Gabrielle Boucher,Stephan Brand,Carsten Büning,Ariella Cohain,Sven Cichon,Mauro D'Amato,Dirk De Jong,Kathy L Devaney,Marla Dubinsky,Cathryn Edwards,David Ellinghaus,Lynnette R. Ferguson,Denis Franchimont,Karin Fransen,Richard B. Gearry,Michel Georges,Christian Gieger,Jürgen Glas,Talin Haritunians,Ailsa Hart,Christopher J. Hawkey,Matija Hedl,Xinli Hu,Tom H. Karlsen,Limas Kupčinskas,Subra Kugathasan,Anna Latiano,Debby Laukens,Ian C. Lawrance,Charlie W. Lees,Edouard Louis,Gillian Mahy,John C. Mansfield,Angharad R. Morgan,Craig Mowat,William G. Newman,Orazio Palmieri,Cyriel Y. Ponsioen,Uroš Potočnik,Natalie J. Prescott,Miguel Regueiro,Jerome I. Rotter,Richard K Russell,Jeremy D. Sanderson,Miquel Sans,Jack Satsangi,Stefan Schreiber,Lisa A. Simms,Jurgita Sventoraityte,Stephan R. Targan,Kent D. Taylor,Mark Tremelling,Hein W. Verspaget,Martine De Vos,Cisca Wijmenga,David C. Wilson,Juliane Winkelmann,Ramnik J. Xavier,Sebastian Zeissig,Bin Zhang,Clarence K. Zhang,Hongyu Zhao,Mark S. Silverberg,Vito Annese,Hakon Hakonarson,Steven R. Brant,Graham L. Radford-Smith,Christopher G. Mathew,John D. Rioux,Eric E. Schadt,Mark J. Daly,Andre Franke,Miles Parkes,Severine Vermeire,Jeffrey C. Barrett,Judy H. Cho +105 more