The Burden of Mortality Attributable to Diabetes: Realistic estimates for the year 2000
Gojka Roglic,Nigel Unwin,Peter H. Bennett,Colin Mathers,Jaakko Tuomilehto,Satyajit Nag,Vincent Connolly,Hilary King +7 more
TLDR
These are the first global estimates of mortality attributable to diabetes, and diabetes is likely to be the fifth leading cause of death globally.Abstract:
OBJECTIVE —To estimate the global number of excess deaths due to diabetes in the year 2000. RESEARCH DESIGN AND METHODS —We used a computerized generic formal disease model (DisMod II), used by the World Health Organization to assess disease burden through modeling the relationships between incidence, prevalence, and disease-specific mortality. Baseline input data included population structure, age- and sex-specific estimates of diabetes prevalence, and available published estimates of relative risk of death for people with diabetes compared with people without diabetes. The results were validated with population-based observations and independent estimates of relative risk of death. RESULTS —The excess global mortality attributable to diabetes in the year 2000 was estimated to be 2.9 million deaths, equivalent to 5.2% of all deaths. Excess mortality attributable to diabetes accounted for 2–3% of deaths in poorest countries and over 8% in the U.S., Canada, and the Middle East. In people 35–64 years old, 6–27% of deaths were attributable to diabetes. CONCLUSIONS —These are the first global estimates of mortality attributable to diabetes. Globally, diabetes is likely to be the fifth leading cause of death.read more
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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
Rafael Lozano,Mohsen Naghavi,Kyle J Foreman,Stephen S Lim,Kenji Shibuya,Victor Aboyans,Jerry Abraham,Tim Adair,Rakesh Aggarwal,Stephanie Y. Ahn,Mohammad A. AlMazroa,Miriam Alvarado,H. Ross Anderson,Laurie M. Anderson,Kathryn G. Andrews,Charles Atkinson,Larry M. Baddour,Suzanne Barker-Collo,David Bartels,Michelle L. Bell,Emelia J. Benjamin,Derrick A Bennett,Kavi Bhalla,Boris Bikbov,Aref A. Bin Abdulhak,Gretchen L. Birbeck,Fiona M. Blyth,Ian Bolliger,Soufiane Boufous,Chiara Bucello,Michael Burch,Peter Burney,Jonathan R. Carapetis,Honglei Chen,David Chou,Sumeet S. Chugh,Luc E. Coffeng,Steven D. Colan,Samantha M. Colquhoun,K. Ellicott Colson,John R. Condon,Myles Connor,Myles Connor,Leslie T. Cooper,Matthew A. Corriere,Monica Cortinovis,Karen Courville De Vaccaro,William G. Couser,Benjamin C Cowie,Michael H. Criqui,Marita Cross,Kaustubh Dabhadkar,Nabila Dahodwala,Diego De Leo,Louisa Degenhardt,Allyne Delossantos,Julie O. Denenberg,Don C. Des Jarlais,Samath D Dharmaratne,Samath D Dharmaratne,E. Ray Dorsey,Tim Driscoll,Herbert C. Duber,Beth E. Ebel,Patricia J. Erwin,Patricia Espindola,Majid Ezzati,Valery L. Feigin,Abraham D. Flaxman,Mohammad H. Forouzanfar,F.G.R. Fowkes,Richard C. Franklin,Marlene Fransen,Michael Freeman,Sherine E. Gabriel,Emmanuela Gakidou,Flavio Gaspari,Richard F. Gillum,Diego Gonzalez-Medina,Yara A. Halasa,Diana Haring,James Harrison,Rasmus Havmoeller,Rasmus Havmoeller,Roderick J. Hay,Bruno Hoen,Peter J. Hotez,Damian G Hoy,Kathryn H. Jacobsen,Spencer L. James,Rashmi Jasrasaria,Sudha Jayaraman,Nicole E. Johns,Ganesan Karthikeyan,Nicholas J Kassebaum,Andre Keren,Jon Paul Khoo,Lisa M. Knowlton,Olive Kobusingye,Adofo Koranteng,Rita Krishnamurthi,Michael S Lipnick,Steven E. Lipshultz,Summer Lockett Ohno,Jacqueline Mabweijano,Jacqueline Mabweijano,Michael F. Macintyre,Leslie Mallinger,Lyn March,Guy B. Marks,Robin Marks,Akira Matsumori,Richard Matzopoulos,Richard Matzopoulos,Bongani M. Mayosi,John H. McAnulty,Mary M. McDermott,John J. McGrath,Ziad A. Memish,George A. Mensah,Tony R. Merriman,Catherine Michaud,Matthew J. Miller,Ted R. Miller,Charles Mock,Ana Olga Mocumbi,Ali A. Mokdad,Andrew E. Moran,Kim Mulholland,M. Nathan Nair,Luigi Naldi,K.M. Venkat Narayan,Kiumarss Nasseri,Paul Norman,Martin O'Donnell,Saad B. Omer,Katrina F Ortblad,Richard H. Osborne,Doruk Ozgediz,Bishnu Pahari,Jeyaraj D Pandian,Andrea Panozo Rivero,Rogelio Perez Padilla,Fernando Perez-Ruiz,Norberto Perico,David Phillips,Kelsey Pierce,C. Arden Pope,Esteban Porrini,Farshad Pourmalek,Murugesan Raju,Dharani Ranganathan,Jürgen Rehm,David B. Rein,G. Remuzzi,Frederick P. Rivara,Thomas Roberts,Felipe Rodriguez De Leòn,Lisa C. Rosenfeld,Lesley Rushton,Ralph L. Sacco,Joshua A. Salomon,Uchechukwu Sampson,Ella Sanman,David C. Schwebel,Maria Segui-Gomez,Donald S. Shepard,David Singh,Jessica Singleton,Karen Sliwa,Emma Smith,Andrew C Steer,Jennifer A. Taylor,Bernadette Thomas,Imad M. Tleyjeh,Jeffrey A. Towbin,Thomas Truelsen,Eduardo A. Undurraga,Narayanaswamy Venketasubramanian,Lakshmi Vijayakumar,Theo Vos,Gregory R. Wagner,Mengru Wang,Wenzhi Wang,Kerrianne Watt,Martin A. Weinstock,Robert G. Weintraub,James D. Wilkinson,Anthony D. Woolf,Sarah Wulf,Pon Hsiu Yeh,Paul S. F. Yip,Azadeh Zabetian,Zhi Jie Zheng,Alan D. Lopez,Christopher J L Murray +195 more
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.
Journal ArticleDOI
10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study.
William C. Knowler,Sarah E. Fowler,Richard F. Hamman,Costas A. Christophi,Heather J. Hoffman,Anne T Brenneman,J. Brown-Friday,Ronald N. Goldberg,Elizabeth M. Venditti,David M. Nathan +9 more
TL;DR: During follow-up after DPP, incidences in the former placebo and metformin groups fell to equal those in theFormer lifestyle group, but the cumulative incidence of diabetes remained lowest in the lifestyle group.
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Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus
David B. Sacks,David E. Bruns,David E. Goldstein,Noel K. Maclaren,Jay M. McDonald,Jay M. McDonald,Marian Parrott +6 more
TL;DR: New guidelines for laboratory testing for patients with diabetes mellitus provide specific recommendations that are based on published data or derived from expert consensus, and several analytes have minimal clinical value at present and are not recommended.
Journal ArticleDOI
The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study
Guangwei Li,Ping Zhang,Jinping Wang,Edward W. Gregg,Wenying Yang,Qiuhong Gong,Hui Li,Hongliang Li,Yayun Jiang,Yali An,Ying Shuai,Bo Zhang,Jing-ling Zhang,Theodore J. Thompson,Robert B. Gerzoff,Gojka Roglic,Yinghua Hu,Peter H. Bennett +17 more
TL;DR: Group-based lifestyle interventions over 6 years can prevent or delay diabetes for up to 14 years after the active intervention, however, whether lifestyle intervention also leads to reduced CVD and mortality remains unclear.
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Epidemiologic and economic consequences of the global epidemics of obesity and diabetes
TL;DR: In this article, the authors present quantitative estimates of the epidemiological and economic impact of obesity and diabetes on developing countries, and stress the importance of creating a roadmap to guide the development of comprehensive policies involving governments and private companies.
References
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Journal ArticleDOI
Global Prevalence of Diabetes: Estimates for the year 2000 and projections for 2030
TL;DR: Findings indicate that the "diabetes epidemic" will continue even if levels of obesity remain constant, and given the increasing prevalence of obesity, it is likely that these figures provide an underestimate of future diabetes prevalence.
Journal ArticleDOI
Mortality by cause for eight regions of the world: Global Burden of Disease Study
TL;DR: The Global Burden of Disease Study (GBD) used various data sources and made corrections for miscoding of important diseases (eg, ischaemic heart disease) to estimate worldwide and regional cause-of-death patterns in 1990, and the estimates by cause provide a foundation for a more informed debate on public-health priorities.
Journal Article
Glucose tolerance and mortality: comparison of WHO and American Diabetes Association diagnostic criteria
Knut Borch-Johnsen,Andrew Neil,Beverley Balkau,S Larsen,Aulikki Nissinen,Juha Pekkanen,Keinänen-Kiukaanniemi S,L. Hiltunen,Sirkka-Liisa Kivelä,Jaakko Tuomilehto,P. Jousilahti,Jon Lindstrom,M. Pyorala,Kalevi Pyörälä,Eveline Eschwège,G. Gallus,M.P. Garancini,A Schranz,Robert J. Heine,J.M. Dekker,Edith J. M. Feskens,H Lithell,Björn Zethelius,M Peltonen,Nigel Unwin,N. Ahmad,K. G. M. M. Alberti,M.M. Alberti,Johan G. Eriksson,Qing Qiao +29 more
Journal ArticleDOI
Mortality and causes of death in the WHO Multinational Study of Vascular Disease in Diabetes.
TL;DR: This study confirms the importance of cardiovascular disease as the major cause of death in people with both types of diabetes and confirms the low excess mortality in the Tokyo cohort could have implications for the possible reduction of the burden of mortality associated with diabetes in other parts of the world.
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