The microenvironment in mature B-cell malignancies: a target for new treatment strategies
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TLDR
A paradigm shift in the treatment of selected B-cell malignancies is anticipated, moving from targeting primarily the malignant cells toward combining cytotoxic drugs with agents that interfere with the microenvironment's proactive role.About:
This article is published in Blood.The article was published on 2009-10-15 and is currently open access. It has received 543 citations till now.read more
Citations
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Journal ArticleDOI
Prognostic Factors in Pediatric Classical Hodgkin Lymphoma: Concepts, Questions and Perspectives
Mário Henrique M. Barros,Adriana Morais,Vera Lúcia Lins de Morais,Rocio Hassan,Maria Tereza Cartaxo Muniz +4 more
TL;DR: Identifying clinical and biological factors that allow discrimination of patients who may undergo a reduction in treatment intensity is a current goal to reduce late effects of Hodggkin´s Lymphoma.
Journal ArticleDOI
The times they are a-changin': prognostic markers in the new era of BCR-targeting therapies for CLL
TL;DR: With the emergence of inhibitors of BCR-associated kinases (Btk-, Syk- and PI3 kinase inhibitors) in CLL and other B cell malignancies, B CR-related risk factors may help with identification of patients who are likely to respond and/or for response assessment (i.e., CCL3 plasma levels).
Proceedings ArticleDOI
Cytotoxic properties of nanostructures based on aluminum oxide and hydroxide phases
TL;DR: In this article, the authors studied the cytotoxic properties of low-dimensional nanostructures based on aluminum oxide and hydroxide phases with the morphology of agglomerated crumpled nanosheets.
Dissertation
Paper de la proteïna ZAP-70 en la regulació de la interacció de la leucèmia limfàtica crònica amb el microambient
TL;DR: In this paper, a proteina ZAP-70 has been used for the management of leucemia mes comu al mon occidental, a malaltia clinicament molt heterogenia.
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