The thiol pool in human plasma: the central contribution of albumin to redox processes.
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TLDR
A critical review of the plasma thiol pool is provided with a focus on human serum albumin, an important target for oxidants and electrophiles due to its reactivity with a wide variety of species and its relatively high concentration.About:
This article is published in Free Radical Biology and Medicine.The article was published on 2013-12-01 and is currently open access. It has received 519 citations till now. The article focuses on the topics: Human serum albumin & Thiol.read more
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Dynamic Thiol Disulphide Homeostasis In Patients Diagnosed With Acute Pulmonary Thromboembolism In Emergency Department
Gul Pamukcu Gunaydin,Fatih Tanriverdi,Serkan Demircan,Ferhat Icme,Yavuz Otal,Yücel Yüzbaşıoğlu,erdem haytaç,Pervin Baran,Cemile Bicer +8 more
TL;DR: Thiol-disulfide balance is altered oxidatively in patients with pulmonary embolism, which may play a role in the pathogenesis of the disease.
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Redox-Enabled Bio-Electronics for Information Acquisition and Transmission
Yi Liu,Eunkyoung Kim,Dana Motabar,Zhi-qing Zhao,Deanna L. Kelly,William E. Bentley,Gregory F. Payne +6 more
TL;DR: A review of recent efforts to develop redox-based bioelectronics for the acquisition of information and actuation of responses can be found in this article , where electrodes enable comparatively simple modulation/demodulation because electrodes readily transduce electrical inputs into redox signals.
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Global Discovery and Temporal Changes of Human Albumin Modifications by Pan-Protein Adductomics: Initial Application to Air Pollution Exposure.
Joshua W. Smith,Robert N. O'Meally,Sean M. Burke,Derek K. Ng,Jianguo Chen,Thomas W. Kensler,John D. Groopman,Robert N. Cole +7 more
TL;DR: The Pan-Protein adductomics (PPA) technology reported in this paper is the next step toward an unbiased, comprehensive characterization of the human serum albumin (HSA)-based biomonitoring, using nanoflow-liquid chromatography, gas phase fractionation, and overlapping-window data-independent acquisition high-resolution tandem mass spectrometry.
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Organic Selenocompounds: are they the panacea to human illnesses?
J. B. Teixeira Rocha,Pablo A. Nogara,Meire Ellen Pereira,Cláudia Sirlene de Oliveira,Laura Orian +4 more
TL;DR: The selenium element is essential of some life forms and its biological-chemistry function is mainly performed by the selenol/selenolate moiety (-SeH/-Se-) in a few selenoproteins as mentioned in this paper .
References
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Bilirubin is an antioxidant of possible physiological importance
TL;DR: The data support the idea of a "beneficial" role for bilirubin as a physiological, chain-breaking antioxidant.
Book
All About Albumin: Biochemistry, Genetics, and Medical Applications
TL;DR: The Albumin Molecule: Its Structure and Chemical Properties and Practical Aspects: Albumin in the Laboratory.
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Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide.
TL;DR: Peroxynitrite anion was a less effective thiol-oxidizing agent than its anion, with oxidation presumably mediated by the decomposition products, hydroxyl radical and nitrogen dioxide.
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Homocysteine and Cardiovascular Disease
TL;DR: In this article, an elevated level of total homocysteine (tHcy) in blood, denoted hyperhomocysteinemia, is emerging as a prevalent and strong risk factor for atherosclerotic vascular disease in the coronary, cerebral, and peripheral vessels, and for arterial and venous thromboembolism.
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Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles.
TL;DR: This review gives an account of the different drug delivery systems which make use of albumin as a drug carrier with a focus on those systems that have reached an advanced stage of preclinical evaluation or that have entered clinical trials.