The thiol pool in human plasma: the central contribution of albumin to redox processes.
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TLDR
A critical review of the plasma thiol pool is provided with a focus on human serum albumin, an important target for oxidants and electrophiles due to its reactivity with a wide variety of species and its relatively high concentration.About:
This article is published in Free Radical Biology and Medicine.The article was published on 2013-12-01 and is currently open access. It has received 519 citations till now. The article focuses on the topics: Human serum albumin & Thiol.read more
Citations
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Journal ArticleDOI
Ischemia-Modified Albumin Levels and Thiol-Disulphide Homeostasis in Diabetic Macular Edema in Patients with Diabetes Mellitus Type 2.
Mustafa Kalayci,Ersan Çetinkaya,Kenan Yigit,Mehmet Cem Sabaner,Reşat Duman,Ahmet Rifat Balik,Ozcan Erel +6 more
TL;DR: The disruption in thiol/disulphide homeostasis, increased IMA and oxidative stress have an impact on the development of diabetic macular edema.
Dissertation
Preparation of Thiol Conjugates of the Mycotoxin Deoxynivalenol and their Occurrence in Nature
Journal ArticleDOI
Measurement of S-glutathionylated proteins by HPLC
TL;DR: In this paper, a method for quantifying s-glutathionylated proteins (GSSP) is proposed, which can be applied to many different biological samples, comprising blood components, red blood cell plasma membrane, cultured cells, and solid organs from animal models.
Journal ArticleDOI
Investigation of Dynamic Thiol/Disulfide Homeostasis in Children With Acute Immune Thrombocytopenia.
Husam Beyazit,Abdullah T. Demiryürek,Munevver Tugba Temel,Esra Pekpak,Seniz Demiryürek,Sinan Akbayram +5 more
TL;DR: It is demonstrated that thiol/disulfide homeostasis plays a role in ITP pathogenesis, and IVIG treatment can prevent the reduced thiol levels in children.
Journal ArticleDOI
Investigation of adropin and IMA levels in psoriasis and their relation to duration and severity of disease
Suzan Demir Pektas,Gökhan Pektaş,Aynure Öztekin,Tuba Gökdoğan Edgünlü,Sevim Karakas-Celik,Salim Neselioglu,Ozcan Erel +6 more
TL;DR: The increased incidence of cardio-metabolic diseases in psoriasis is caused by underlying systemic inflammation together with ABSTRACT.
References
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Bilirubin is an antioxidant of possible physiological importance
TL;DR: The data support the idea of a "beneficial" role for bilirubin as a physiological, chain-breaking antioxidant.
Book
All About Albumin: Biochemistry, Genetics, and Medical Applications
TL;DR: The Albumin Molecule: Its Structure and Chemical Properties and Practical Aspects: Albumin in the Laboratory.
Journal ArticleDOI
Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide.
TL;DR: Peroxynitrite anion was a less effective thiol-oxidizing agent than its anion, with oxidation presumably mediated by the decomposition products, hydroxyl radical and nitrogen dioxide.
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Homocysteine and Cardiovascular Disease
TL;DR: In this article, an elevated level of total homocysteine (tHcy) in blood, denoted hyperhomocysteinemia, is emerging as a prevalent and strong risk factor for atherosclerotic vascular disease in the coronary, cerebral, and peripheral vessels, and for arterial and venous thromboembolism.
Journal ArticleDOI
Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles.
TL;DR: This review gives an account of the different drug delivery systems which make use of albumin as a drug carrier with a focus on those systems that have reached an advanced stage of preclinical evaluation or that have entered clinical trials.