The thiol pool in human plasma: the central contribution of albumin to redox processes.
Reads0
Chats0
TLDR
A critical review of the plasma thiol pool is provided with a focus on human serum albumin, an important target for oxidants and electrophiles due to its reactivity with a wide variety of species and its relatively high concentration.About:
This article is published in Free Radical Biology and Medicine.The article was published on 2013-12-01 and is currently open access. It has received 519 citations till now. The article focuses on the topics: Human serum albumin & Thiol.read more
Citations
More filters
Journal ArticleDOI
Doğum-Sütten Kesim Dönemi Aralığında Besiye Alınan Kuzularda Beslenme Dönemlerinin Oksidatif Stres Düzeyleri Üzerindeki Etkileri
TL;DR: In this paper , the authors used 40 newborn singleton Akkaraman and Merino lambs with 4 trial groups consisting of selected 10 lambs homogeneous according to race and gender.
Journal ArticleDOI
Alteration of serum biomarkers in patients with hypertrophic cardiomyopathy with and without atrial fibrillation.
Munevver Sari,Hayrullah Yazar,Ibrahim Kocayigit,Ali Karagöz,Mehmet Aytürk,Serdar Fidan,Ugur Arslantas,Ender Özgün Çakmak,Gökhan Alıcı,Birol Özkan +9 more
TL;DR: In this article, the relationship between presence of atrial fibrillation and serum biomarkers, including native thiol (antioxidant), disulphide/native thiol ratio, Hs-CRP and high-sensitivity Troponin-I (Hs-TnI) in hypertrophic cardiomyopathy (HCM), was determined.
Journal ArticleDOI
Alteration of thiol disulfide homeostasis and ischemia-modified albumin levels as indicators of oxidative status in patients with silicosis.
Mevlüt Karataş,Murat Büyükşekerci,Meşide Gündüzöz,Gökhan Özakinci,Türkan Nadir Öziş,Gamze Gok,Salim Neselioglu,Ozcan Erel +7 more
TL;DR: A novel colorimetric method is used to assess TDH in patients with silicosis by detecting dynamic thiol disulfide homeostasis (TDH), ischemia-modified albumin level (IMA) catalase (CAT) activity, and the correlation of these markers with pulmonary function tests.
DissertationDOI
Synthesis, Characterization, and Evaluation of Small Molecule-based Fluorogenic Probes for the Detection of Cellular Thiols
TL;DR: In this article , the HMBQ-Nap 1 and DCM-Cys probes were used to detect the free thiols glutathione, cysteine, and homocysteine.
Journal ArticleDOI
Three asymmetric BODIPY derivatives as fluorescent probes for highly selective and sensitive detection of cysteine in living cells.
Jinlei Yue,Nannan Wang,Jiamin Wang,Yuanfang Tao,Han Wang,Jinying Liu,Jian Zhang,Junrong Jiao,Weili Zhao +8 more
TL;DR: Wang et al. as discussed by the authors designed and synthesized three new asymmetric fluorescent probes (BDP-S-Ph, BDP- S-ENE and BDPS-R) to discriminate Cys from Hcy/GSH.
References
More filters
Journal ArticleDOI
Bilirubin is an antioxidant of possible physiological importance
TL;DR: The data support the idea of a "beneficial" role for bilirubin as a physiological, chain-breaking antioxidant.
Book
All About Albumin: Biochemistry, Genetics, and Medical Applications
TL;DR: The Albumin Molecule: Its Structure and Chemical Properties and Practical Aspects: Albumin in the Laboratory.
Journal ArticleDOI
Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide.
TL;DR: Peroxynitrite anion was a less effective thiol-oxidizing agent than its anion, with oxidation presumably mediated by the decomposition products, hydroxyl radical and nitrogen dioxide.
Journal ArticleDOI
Homocysteine and Cardiovascular Disease
TL;DR: In this article, an elevated level of total homocysteine (tHcy) in blood, denoted hyperhomocysteinemia, is emerging as a prevalent and strong risk factor for atherosclerotic vascular disease in the coronary, cerebral, and peripheral vessels, and for arterial and venous thromboembolism.
Journal ArticleDOI
Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles.
TL;DR: This review gives an account of the different drug delivery systems which make use of albumin as a drug carrier with a focus on those systems that have reached an advanced stage of preclinical evaluation or that have entered clinical trials.