The thiol pool in human plasma: the central contribution of albumin to redox processes.
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TLDR
A critical review of the plasma thiol pool is provided with a focus on human serum albumin, an important target for oxidants and electrophiles due to its reactivity with a wide variety of species and its relatively high concentration.About:
This article is published in Free Radical Biology and Medicine.The article was published on 2013-12-01 and is currently open access. It has received 519 citations till now. The article focuses on the topics: Human serum albumin & Thiol.read more
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Evaluation of thiol-disulphide homeostasis in patients with chronic hepatitis B
TL;DR: Amac: HBV DNA seviyeleri ile yeni bir oksidatif stres belirteci olan dinamik tiyol-disulfit homeostazi ve oksidan-antioksidan dengesi arasindaki iliskiyi degerlendirmektir.
Posted ContentDOI
Young and Undamaged rMSA Improves the Longevity of Mice
Jiaze Tang,Anji Ju,Boya Li,Silin Zhang,Yuanchao Gong,Boyuan Ma,Yale Jiang,Hongyan Liu,Yan Fu,Yanting Luo +9 more
TL;DR: In this article, a single protein recombinant mouse serum albumin (rMSA) was used to improve the lifespan and healthspan of C57BL/6N mice.
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The Role of Thiol/Disulfide Homeostasis in the Differentiation of Transudative and Exudative Pleural Effusion, Running Title: Pleural Fluid of Thiol/Disulfide Homeostasis
Osama Abuzaina,Habibe Hezer,Ayşegül Karalezli,Seray Abuzaina,Salim Neselioglu,Ozcan Erel,H. Canan Hasanoglu +6 more
TL;DR: The increased disulfide levels are indicative of increased oxidative stress in exudative pleural fluid, which may be a major factor in the pathogenesis.
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Evaluation of levels of oxidants and antioxidants stress markers in saliva and serum of patients with recurrent aphthous stomatitis (RAS)
TL;DR: Evaluation of levels of oxidants and antioxidants stress markers in saliva and serum of patients with recurrent aphthous stomatitis found some of them more than the others with interference not completely clear therefore more clinical studies are required.
References
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Bilirubin is an antioxidant of possible physiological importance
TL;DR: The data support the idea of a "beneficial" role for bilirubin as a physiological, chain-breaking antioxidant.
Book
All About Albumin: Biochemistry, Genetics, and Medical Applications
TL;DR: The Albumin Molecule: Its Structure and Chemical Properties and Practical Aspects: Albumin in the Laboratory.
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Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide.
TL;DR: Peroxynitrite anion was a less effective thiol-oxidizing agent than its anion, with oxidation presumably mediated by the decomposition products, hydroxyl radical and nitrogen dioxide.
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Homocysteine and Cardiovascular Disease
TL;DR: In this article, an elevated level of total homocysteine (tHcy) in blood, denoted hyperhomocysteinemia, is emerging as a prevalent and strong risk factor for atherosclerotic vascular disease in the coronary, cerebral, and peripheral vessels, and for arterial and venous thromboembolism.
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Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles.
TL;DR: This review gives an account of the different drug delivery systems which make use of albumin as a drug carrier with a focus on those systems that have reached an advanced stage of preclinical evaluation or that have entered clinical trials.