The thiol pool in human plasma: the central contribution of albumin to redox processes.
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TLDR
A critical review of the plasma thiol pool is provided with a focus on human serum albumin, an important target for oxidants and electrophiles due to its reactivity with a wide variety of species and its relatively high concentration.About:
This article is published in Free Radical Biology and Medicine.The article was published on 2013-12-01 and is currently open access. It has received 519 citations till now. The article focuses on the topics: Human serum albumin & Thiol.read more
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Dynamic thiol/disulfide homeostasis in children with community-acquired pneumonia.
Munevver Tugba Temel,Seniz Demiryürek,Levent Temel,Ahmet Saracaloglu,Necmi Eke,Elif Baysalman,Azad Mammadov,Mehmet Enes Coskun,Abdullah T. Demiryürek +8 more
TL;DR: Alteration in thiol level under oxidative stress may contribute to community‐acquired pneumonia (CAP) and there are changes inThiol/disulfide homeostasis and nitric oxide in children with CAP.
Journal ArticleDOI
Evaluation of Dynamic Disulphide/Thiol Homeostasis in Silica Exposed Workers.
Meşide Gündüzöz,Ceylan Bal,Murat Büyükşekerci,Salim Neselioglu,Türkan Nadir Öziş,Servet Birgin Iritas,Halil Kara,Ozcan Erel +7 more
TL;DR: The serum disulphide levels, a biomarker of oxidative stress, are found to be higher in silica-exposed workers.
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The Effects of Bilirubin and Phototherapy on Neonatal Thiol-Disulfide Homeostasis.
TL;DR: Bilirubin showed antioxidant effect without increasing oxidative stress in newborns and Oxidative stress increased after phototherapy, associated with decrease in bilirUBin rather than oxidative effect of phototherapy.
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Evaluation of Thiol Homeostasis in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders.
TL;DR: In this paper, the authors evaluated dynamic thiol-disulfide homeostasis as a novel oxidative stress parameter in multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD), and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) to better understand the role of thiol in neuroimmunological diseases.
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Role of native Thiol, total Thiol and dynamic Disulphide in diagnosis of patient with prostate cancer and prostatitis
TL;DR: Serum NT, TT, DD levels in patients with prostatitis and prostate cancer were found significantly lower compared to the control group, indicating that just as inflammation, prostate cancer also increases oxidative stress on tissues.
References
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Bilirubin is an antioxidant of possible physiological importance
TL;DR: The data support the idea of a "beneficial" role for bilirubin as a physiological, chain-breaking antioxidant.
Book
All About Albumin: Biochemistry, Genetics, and Medical Applications
TL;DR: The Albumin Molecule: Its Structure and Chemical Properties and Practical Aspects: Albumin in the Laboratory.
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Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide.
TL;DR: Peroxynitrite anion was a less effective thiol-oxidizing agent than its anion, with oxidation presumably mediated by the decomposition products, hydroxyl radical and nitrogen dioxide.
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Homocysteine and Cardiovascular Disease
TL;DR: In this article, an elevated level of total homocysteine (tHcy) in blood, denoted hyperhomocysteinemia, is emerging as a prevalent and strong risk factor for atherosclerotic vascular disease in the coronary, cerebral, and peripheral vessels, and for arterial and venous thromboembolism.
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Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles.
TL;DR: This review gives an account of the different drug delivery systems which make use of albumin as a drug carrier with a focus on those systems that have reached an advanced stage of preclinical evaluation or that have entered clinical trials.