White Matter Microstructure and Atypical Visual Orienting in 7-Month-Olds at Risk for Autism
Jed T. Elison,Sarah Paterson,Jason J. Wolff,J. Steven Reznick,Noah J. Sasson,Hongbin Gu,Kelly N. Botteron,Stephen R. Dager,Annette Estes,Alan C. Evans,Guido Gerig,Heather C. Hazlett,Robert T. Schultz,Martin Styner,Lonnie Zwaigenbaum,Joseph Piven +15 more
TLDR
Visual orienting latencies were longer in 7-month-old infants who expressed ASD symptoms at 25 months compared with both high-risk negative infants and low-risk infants, and abnormal functional specialization of posterior cortical circuits directly informs a novel model of ASD pathogenesis.Abstract:
Specific differences in visual orienting, critical in social-cognitive development, are associated with differences in white matter microstructure of the splenium.read more
Citations
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Journal ArticleDOI
Developmental white matter microstructure in autism phenotype and corresponding endophenotype during adolescence
Danuta Lisiecka,Rosemary Holt,Roger Tait,M. Ford,M. Lai,Lindsay R. Chura,Simon Baron-Cohen,Michael D. Spencer,John Suckling +8 more
TL;DR: It is proposed that the alterations of brain connectivity that have a key role in autism spectrum conditions may interact with the development of white matter microstructure and constitute a part of the endophenotype of autism.
Infant Emotion Development and Temperament
Evin Aktar,Koraly Pérez-Edgar +1 more
TL;DR: In this paper, the authors review the relation between emotion and emotion regulation as a function of early temperamental differences, focusing on one relatively thin slice of this network, i.e., emotion, emotion regulation, and temperament.
Journal ArticleDOI
Eurosibs : Towards robust measurement of infant neurocognitive predictors of autism across Europe
Emily J.H. Jones,Luke Mason,J. Begum Ali,C. van den Boomen,Ricarda Braukmann,Elodie Cauvet,Ellen Demurie,Roy S. Hessels,Emma K. Ward,Sabine Hunnius,Sven Bölte,Przemyslaw Tomalski,Chantal Kemner,Petra Warreyn,Herbert Roeyers,Jan K. Buitelaar,Terje Falck-Ytter,Tony Charman,Mark H. Johnson +18 more
TL;DR: Data quality assessments show that that neurocognitive measures hold promise for cross-site consistency in diverse populations and present robust data analysis pipelines and highlight challenges and opportunities for future multisite research efforts.
Journal ArticleDOI
Initiation of joint attention and related visual attention processes in infants with autism spectrum disorder: Literature review.
TL;DR: Results pertaining to retrospective studies of initiation of joint attention in children with ASD and prospective studies of infants at high risk for ASD during the first 2 years, when this behavior is becoming more complex in terms of frequency, quality, and variety are summarized.
Journal ArticleDOI
Exploring cortical activation and connectivity in infants with and without familial risk for autism during naturalistic social interactions: A preliminary study
TL;DR: Functional near-infrared spectroscopy (fNIRS), an infant-friendly neuroimaging tool that is relatively robust against motion artifacts, is used to examine functional activation and connectivity during naturalistic social interactions in 9 high-risk and 6 low-risk infants from 6 to 9 months of age.
References
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Catherine Lord,Susan Risi,Linda Lambrecht,Edwin H. Cook,Bennett L. Leventhal,Pamela C. DiLavore,Andrew Pickles,Michael Rutter +7 more
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