White Matter Microstructure and Atypical Visual Orienting in 7-Month-Olds at Risk for Autism
Jed T. Elison,Sarah Paterson,Jason J. Wolff,J. Steven Reznick,Noah J. Sasson,Hongbin Gu,Kelly N. Botteron,Stephen R. Dager,Annette Estes,Alan C. Evans,Guido Gerig,Heather C. Hazlett,Robert T. Schultz,Martin Styner,Lonnie Zwaigenbaum,Joseph Piven +15 more
TLDR
Visual orienting latencies were longer in 7-month-old infants who expressed ASD symptoms at 25 months compared with both high-risk negative infants and low-risk infants, and abnormal functional specialization of posterior cortical circuits directly informs a novel model of ASD pathogenesis.Abstract:
Specific differences in visual orienting, critical in social-cognitive development, are associated with differences in white matter microstructure of the splenium.read more
Citations
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Journal ArticleDOI
EEG Analytics for Early Detection of Autism Spectrum Disorder: A data-driven approach.
William J. Bosl,William J. Bosl,William J. Bosl,Helen Tager-Flusberg,Charles A. Nelson,Charles A. Nelson +5 more
TL;DR: In this paper, EEG measurements were collected from 99 infants with an older sibling diagnosed with ASD, and 89 low risk controls, beginning at 3 months of age and continuing until 36 months.
Journal ArticleDOI
Annual Research Review: Infant development, autism, and ADHD – early pathways to emerging disorders
TL;DR: A review of the literature highlights points of convergence and divergence in the early pathways to ASD and ADHD in infants who later meet criteria for ASD or ADHD.
Journal ArticleDOI
Efficacy of early interventions for infants and young children with, and at risk for, autism spectrum disorders.
TL;DR: Evidence supports combining parent-mediated and direct clinician-implemented intervention to maximize child developmental gains in young children with ASD.
Journal ArticleDOI
Maternal Systemic Interleukin-6 During Pregnancy Is Associated With Newborn Amygdala Phenotypes and Subsequent Behavior at 2 Years of Age
Alice M. Graham,Jerod M. Rasmussen,Marc D. Rudolph,Christine Heim,John H. Gilmore,Martin Styner,Steven G. Potkin,Sonja Entringer,Pathik D. Wadhwa,Damien A. Fair,Claudia Buss +10 more
TL;DR: Higher average maternal interleukin-6 concentration during pregnancy was prospectively associated with larger right amygdala volume and stronger bilateral amygdala connectivity to brain regions involved in sensory processing and integration and emerging behavioral phenotypes relevant for psychiatric disorders.
Journal ArticleDOI
Speech disturbs face scanning in 6-month-old infants who develop autism spectrum disorder.
TL;DR: It is suggested that infants later diagnosed with ASD have difficulties regulating attention to complex social scenes and the presence of speech might uniquely disturb the attention of infants who later develop ASD at a critical developmental point when other infants are acquiring language and learning about their social world.
References
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