S
Sandra Deming-Halverson
Researcher at Vanderbilt University
Publications - 29
Citations - 4969
Sandra Deming-Halverson is an academic researcher from Vanderbilt University. The author has contributed to research in topics: Breast cancer & Genome-wide association study. The author has an hindex of 19, co-authored 28 publications receiving 3909 citations. Previous affiliations of Sandra Deming-Halverson include Durham University & Vanderbilt University Medical Center.
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Journal ArticleDOI
Risk of COVID-19 among front-line health-care workers and the general community: a prospective cohort study.
Long H. Nguyen,David A. Drew,Mark S. Graham,Amit Joshi,Chuan Guo Guo,Chuan Guo Guo,Wenjie Ma,Raaj S. Mehta,Erica T. Warner,Daniel Sikavi,Chun-Han Lo,Sohee Kwon,Mingyang Song,Lorelei A. Mucci,Meir J. Stampfer,Walter C. Willett,A. Heather Eliassen,Jaime E. Hart,Jorge E. Chavarro,Janet W. Rich-Edwards,Richard Davies,Joan Capdevila,Karla A. Lee,Mary Ni Lochlainn,Thomas Varsavsky,Carole H. Sudre,M. Jorge Cardoso,Jonathan Wolf,Tim D. Spector,Sebastien Ourselin,Claire J. Steves,Andrew T. Chan,Christine M. Albert,Gabriella Andreotti,Bijal Bala,Bijal A. Balasubramanian,Laura Beane-Freeman,John S. Brownstein,Fiona Bruinsma,Joe Coresh,Rui Costa,Annie Cowan,Anusila Deka,Sandra Deming-Halverson,Maria Elena Martinez,Michael E. Ernst,Jane C. Figueiredo,Pedro Fortuna,Paul W. Franks,Laura E. Beane Freeman,Christopher D. Gardner,Irene M. Ghobrial,Christopher A. Haiman,Janet E. Hall,Jae H. Kang,Brenda Kirpach,Karestan C. Koenen,Laura D. Kubzansky,James V. Lacey,Loic Le Marchand,Xihong Lin,Pamela L. Lutsey,Catherine R. Marinac,Roger L. Milne,Anne M. Murray,Denis Nash,Julie R. Palmer,Alpa V. Patel,Eric Pierce,McKaylee Robertson,Lynn Rosenberg,Dale P. Sandler,Shepherd H. Schurman,Kara Sewalk,Shreela V. Sharma,Chris Sidey-Gibbons,Liz Slevin,Jordan W. Smoller,Maarit Tiirikainen,Scott T. Weiss,Lynne R. Wilkens,Feng Zhang +81 more
TL;DR: In the UK and the USA, risk of reporting a positive test for COVID-19 was increased among front-line health-care workers, and adequacy of PPE, clinical setting, and ethnic background were also important factors.
Journal ArticleDOI
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Kyriaki Michailidou,Per Hall,Anna González-Neira,Maya Ghoussaini,Joe Dennis,Roger L. Milne,Marjanka K. Schmidt,Jenny Chang-Claude,Stig E. Bojesen,Manjeet K. Bolla,Qin Wang,Ed Dicks,Andy C. H. Lee,Clare Turnbull,Nazneen Rahman,Olivia Fletcher,Julian Peto,Lorna Gibson,Isabel dos Santos Silva,Heli Nevanlinna,Taru A. Muranen,Kristiina Aittomäki,Carl Blomqvist,Kamila Czene,Astrid K. Irwanto,Jianjun Liu,Quinten Waisfisz,Hanne Meijers-Heijboer,Muriel A. Adank,Rob B. van der Luijt,Rebecca Hein,N. Dahmen,Lars Beckman,Alfons Meindl,Rita K. Schmutzler,Bertram Müller-Myhsok,Peter Lichtner,John L. Hopper,Melissa C. Southey,Enes Makalic,Daniel F. Schmidt,Andre G. Uitterlinden,Albert Hofman,David J. Hunter,Stephen J. Chanock,Daniel Vincent,Francois Bacot,Daniel C. Tessier,Sander Canisius,Lodewyk F. A. Wessels,Christopher A. Haiman,Mitul Shah,Robert Luben,Judith E. Brown,Craig Luccarini,Nils Schoof,Keith Humphreys,Jingmei Li,Børge G. Nordestgaard,Sune F. Nielsen,Henrik Flyger,Fergus J. Couch,Xianshu Wang,Celine M. Vachon,Kristen N. Stevens,Diether Lambrechts,Matthieu Moisse,Robert Paridaens,Marie Rose Christiaens,Anja Rudolph,Stefan Nickels,Dieter Flesch-Janys,Dieter Flesch-Janys,Dieter Flesch-Janys,Nichola Johnson,Zoe Aitken,Kirsimari Aaltonen,Kirsimari Aaltonen,Tuomas Heikkinen,Annegien Broeks,Laura J. Van 'T Veer,C. Ellen van der Schoot,Pascal Guénel,Thérèse Truong,Pierre Laurent-Puig,Florence Menegaux,Frederik Marmé,Andreas Schneeweiss,Christof Sohn,Barbara Burwinkel,M. Pilar Zamora,Jose Ignacio Arias Perez,Guillermo Pita,M. Rosario Alonso,Angela Cox,Ian W. Brock,Simon S. Cross,Malcolm W.R. Reed,Elinor J. Sawyer,Ian Tomlinson,Michael J. Kerin,Nicola Miller,Brian E. Henderson,Fredrick R. Schumacher,Loic Le Marchand,Irene L. Andrulis,Julia A. Knight,Gord Glendon,Anna Marie Mulligan,Annika Lindblom,Sara Margolin,Maartje J. Hooning,Antoinette Hollestelle,Ans M.W. van den Ouweland,Agnes Jager,Quang M. Bui,Jennifer Stone,Gillian S. Dite,Carmel Apicella,Helen Tsimiklis,Graham G. Giles,Gianluca Severi,Laura Baglietto,Peter A. Fasching,Lothar Haeberle,Arif B. Ekici,Matthias W. Beckmann,Hermann Brenner,Heiko Müller,Volker Arndt,Christa Stegmaier,Anthony J. Swerdlow,Alan Ashworth,Nick Orr,Michael Jones,Jonine D. Figueroa,Jolanta Lissowska,Louise A. Brinton,Mark S. Goldberg,Martine Dumont,Robert Winqvist,Katri Pylkäs,Arja Jukkola-Vuorinen,Mervi Grip,Hiltrud Brauch,Ute Hamann,Thomas Brüning,Paolo Radice,Paolo Peterlongo,Siranoush Manoukian,Bernardo Bonanni,Peter Devilee,Rob A. E. M. Tollenaar,Caroline M. Seynaeve,Christi J. van Asperen,Anna Jakubowska,Jan Lubinski,Katarzyna Jaworska,Katarzyna Durda,Arto Mannermaa,Vesa Kataja,Veli-Matti Kosma,Jaana M. Hartikainen,Natalia Bogdanova,Natalia Antonenkova,Thilo Dörk,Vessela N. Kristensen,Hoda Anton-Culver,Susan L. Slager,Amanda E. Toland,Stephen Edge,Florentia Fostira,Daehee Kang,Keun-Young Yoo,Dong Young Noh,Keitaro Matsuo,Hidemi Ito,Hiroji Iwata,Aiko Sueta,Anna H. Wu,Chiu-Chen Tseng,David Van Den Berg,Daniel O. Stram,Xiao-Ou Shu,Wei Lu,Yu Tang Gao,Hui Cai,Soo Hwang Teo,Cheng Har Yip,Sze Yee Phuah,Belinda K. Cornes,Mikael Hartman,Hui Miao,Wei-Yen Lim,J. H. Sng,Kenneth Muir,Artitaya Lophatananon,Sarah Stewart-Brown,Pornthep Siriwanarangsan,Chen-Yang Shen,Chia-Ni Hsiung,Pei Ei Wu,Shian Ling Ding,Suleeporn Sangrajrang,Valerie Gaborieau,Paul Brennan,James McKay,William Blot,Lisa B. Signorello,Qiuyin Cai,Wei Zheng,Sandra Deming-Halverson,Martha J. Shrubsole,Jirong Long,Jacques Simard,M Garcia-Closas,Paul D.P. Pharoah,Georgia Chenevix-Trench,Alison M. Dunning,Javier Benitez,Douglas F. Easton +220 more
TL;DR: A meta-analysis of 9 genome-wide association studies, including 10,052 breast cancer cases and 12,575 controls of European ancestry, and identified 29,807 SNPs for further genotyping suggests that more than 1,000 additional loci are involved in breast cancer susceptibility.
Journal ArticleDOI
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
Stig E. Bojesen,Stig E. Bojesen,Karen A. Pooley,Sharon E. Johnatty,Jonathan Beesley,Kyriaki Michailidou,Jonathan Tyrer,Stacey L. Edwards,Hilda A. Pickett,Hilda A. Pickett,Howard C. Shen,Chanel E. Smart,Kristine M. Hillman,Phuong L. Mai,Kate Lawrenson,Michael D. Stutz,Michael D. Stutz,Yi Lu,Rod Karevan,Nicholas T. Woods,Rebecca L. Johnston,Juliet D. French,Xiaoqing Chen,Maren Weischer,Sune F. Nielsen,Melanie Maranian,Maya Ghoussaini,Shahana Ahmed,Caroline Baynes,Manjeet K. Bolla,Qin Wang,Joe Dennis,Lesley McGuffog,Daniel Barrowdale,Andrew Lee,Sue Healey,Michael Lush,Daniel C. Tessier,Daniel Vincent,Françis Bacot,Ignace Vergote,Sandrina Lambrechts,Evelyn Despierre,Harvey A. Risch,Anna González-Neira,Mary Anne Rossing,Mary Anne Rossing,Guillermo Pita,Jennifer A. Doherty,Nuria Álvarez,Melissa C. Larson,Brooke L. Fridley,Nils Schoof,Jenny Chang-Claude,Mine S. Cicek,Julian Peto,Kimberly R. Kalli,Annegien Broeks,Sebastian M. Armasu,Marjanka K. Schmidt,Linde M. Braaf,Boris Winterhoff,Heli Nevanlinna,Gottfried E. Konecny,Diether Lambrechts,L. Rogmann,Pascal Guénel,Attila Teoman,Roger L. Milne,Joaquin J. Garcia,Angela Cox,Vijayalakshmi Shridhar,Barbara Burwinkel,Frederik Marmé,Rebecca Hein,Rebecca Hein,Elinor J. Sawyer,Christopher A. Haiman,Shan Wang-Gohrke,Irene L. Andrulis,Kirsten B. Moysich,John L. Hopper,Kunle Odunsi,Annika Lindblom,Graham G. Giles,Graham G. Giles,Graham G. Giles,Hermann Brenner,Jacques Simard,Galina Lurie,Peter A. Fasching,Peter A. Fasching,Michael E. Carney,Paolo Radice,Lynne R. Wilkens,Anthony J. Swerdlow,Marc T. Goodman,Hiltrud Brauch,Hiltrud Brauch,Montserrat Garcia-Closas,Peter Hillemanns,Robert Winqvist,Matthias Dürst,Peter Devilee,Ingo B. Runnebaum,Anna Jakubowska,Jan Lubinski,Arto Mannermaa,Ralf Bützow,Natalia Bogdanova,Thilo Dörk,Liisa M. Pelttari,Wei Zheng,Arto Leminen,Hoda Anton-Culver,Clareann H. Bunker,Vessela N. Kristensen,Roberta B. Ness,Kenneth Muir,Kenneth Muir,Robert Edwards,Alfons Meindl,Florian Heitz,Keitaro Matsuo,Andreas du Bois,Anna H. Wu,Philipp Harter,Soo Hwang Teo,Ira Schwaab,Xiao-Ou Shu,William Blot,Satoyo Hosono,Daehee Kang,Toru Nakanishi,Mikael Hartman,Mikael Hartman,Yasushi Yatabe,Ute Hamann,Beth Y. Karlan,Suleeporn Sangrajrang,Susanne K. Kjaer,Valerie Gaborieau,Allan Jensen,Diana Eccles,Estrid Høgdall,Chen-Yang Shen,Chen-Yang Shen,Judith E. Brown,Yin Ling Woo,Mitul Shah,Mat Adenan Noor Azmi,Robert Luben,Siti Zawiah Omar,Kamila Czene,Robert A. Vierkant,Børge G. Nordestgaard,Henrik Flyger,Celine M. Vachon,Janet E. Olson,Xianshu Wang,Douglas A. Levine,Anja Rudolph,Rachel Palmieri Weber,Dieter Flesch-Janys,Edwin S. Iversen,Stefan Nickels,Joellen M. Schildkraut,Isabel dos Santos Silva,Daniel W. Cramer,Lorna Gibson,Kathryn L. Terry,Olivia Fletcher,Allison F. Vitonis,C. Ellen van der Schoot,Elizabeth M. Poole,Frans B. L. Hogervorst,Shelley S. Tworoger,Jianjun Liu,Elisa V. Bandera,Jingmei Li,Sara H. Olson,Keith Humphreys,Irene Orlow,Carl Blomqvist,Lorna Rodriguez-Rodriguez,Kristiina Aittomäki,Helga B. Salvesen,Taru A. Muranen,Elisabeth Wik,Barbara Brouwers,Camilla Krakstad,Els Wauters,Mari K. Halle,Hans Wildiers,Lambertus A. Kiemeney,Claire Mulot,Katja K.H. Aben,Pierre Laurent-Puig,Anne M. van Altena,Thérèse Truong,Leon F.A.G. Massuger,Javier Benitez,Tanja Pejovic,Jose Ignacio Arias Perez,Maureen E. Hoatlin,M. Pilar Zamora,Linda S. Cook,Sabapathy P. Balasubramanian,Linda E. Kelemen,Andreas Schneeweiss,Nhu D. Le,Christof Sohn,Angela Brooks-Wilson,Angela Brooks-Wilson,Ian Tomlinson,Michael J. Kerin,Nicola Miller,Cezary Cybulski,Brian E. Henderson,Janusz Menkiszak,Fredrick R. Schumacher,Nicolas Wentzensen,Loic Le Marchand,Hannah P. Yang,Anna Marie Mulligan,Gord Glendon,Svend Aage Engelholm,Julia A. Knight,Claus Høgdall,Carmel Apicella,Martin Gore,Helen Tsimiklis,Honglin Song,Melissa C. Southey,Agnes Jager,Ans M Wvan Den Ouweland,Robert S. Brown,John W.M. Martens,James M. Flanagan,Mieke Kriege,James Paul,Sara Margolin,Nadeem Siddiqui,Gianluca Severi,Gianluca Severi,Alice S. Whittemore,Laura Baglietto,Laura Baglietto,Valerie McGuire,Christa Stegmaier,Weiva Sieh,Heiko Müller,Volker Arndt,Yu Tang Gao,Mark S. Goldberg,Gong Yang,Martine Dumont,John R. McLaughlin,Arndt Hartmann,Arif B. Ekici,Matthias W. Beckmann,Catherine M. Phelan,Michael P. Lux,Jenny Permuth-Wey,Bernard Peissel,Thomas A. Sellers,Filomena Ficarazzi,Monica Barile,Argyrios Ziogas,Alan Ashworth,Aleksandra Gentry-Maharaj,Michael Jones,Susan J. Ramus,Nick Orr,Usha Menon,Celeste Leigh Pearce,Thomas Brüning,Malcolm C. Pike,Malcolm C. Pike,Yon Ko,Jolanta Lissowska,Jonine D. Figueroa,Jolanta Kupryjanczyk,Stephen J. Chanock,Agnieszka Dansonka-Mieszkowska,Arja Jukkola-Vuorinen,Iwona K. Rzepecka,Katri Pylkäs,Mariusz Bidziński,Saila Kauppila,Antoinette Hollestelle,Caroline Seynaeve,Rob A. E. M. Tollenaar,Katarzyna Durda,Katarzyna Jaworska,Katarzyna Jaworska,Jaana M. Hartikainen,Veli-Matti Kosma,Vesa Kataja,Natalia Antonenkova,Jirong Long,Martha J. Shrubsole,Sandra Deming-Halverson,Artitaya Lophatananon,Artitaya Lophatananon,Pornthep Siriwanarangsan,Sarah Stewart-Brown,Nina Ditsch,Peter Lichtner,Rita K. Schmutzler,Hidemi Ito,Hiroji Iwata,Kazuo Tajima,Chiu-Chen Tseng,Daniel O. Stram,David Van Den Berg,Cheng Har Yip,M. Kamran Ikram,Yew Ching Teh,Hui Cai,Wei Lu,Lisa B. Signorello,Qiuyin Cai,Dong Young Noh,Keun-Young Yoo,Hui Miao,Philip Iau,Yik Ying Teo,James McKay,Charles L. Shapiro,Foluso O. Ademuyiwa,George Fountzilas,Chia-Ni Hsiung,Jyh Cherng Yu,Ming-Feng Hou,Catherine S. Healey,Craig Luccarini,Susan Peock,Dominique Stoppa-Lyonnet,Paolo Peterlongo,Timothy R. Rebbeck,Marion Piedmonte,Christian F. Singer,Eitan Friedman,Mads Thomassen,Kenneth Offit,Thomas Hansen,Susan L. Neuhausen,Csilla Szabo,Ignacio Blanco,Judy Garber,Steven A. Narod,Jeffrey N. Weitzel,Marco Montagna,Edith Olah,Andrew K. Godwin,Drakoulis Yannoukakos,David E. Goldgar,Trinidad Caldés,Evgeny N. Imyanitov,Laima Tihomirova,Banu Arun,Ian G. Campbell,Arjen R. Mensenkamp,Christi J. van Asperen,Kees E. P. van Roozendaal,Hanne Meijers-Heijboer,J. Margriet Collée,Jan C. Oosterwijk,Maartje J. Hooning,Matti A. Rookus,Rob B. van der Luijt,Theo A. Mvan Os,D. Gareth Evans,Debra Frost,Elena Fineberg,Julian Barwell,Lisa Walker,M. John Kennedy,Radka Platte,Rosemarie Davidson,Steve Ellis,Trevor Cole,Brigitte Bressac-de Paillerets,Bruno Buecher,Francesca Damiola,Laurence Faivre,Marc Frenay,Olga M. Sinilnikova,Olivier Caron,Sophie Giraud,Sylvie Mazoyer,Valérie Bonadona,Virginie Caux-Moncoutier,Aleksandra Tołoczko-Grabarek,Jacek Gronwald,Tomasz Byrski,Amanda B. Spurdle,Bernardo Bonanni,Daniela Zaffaroni,Giuseppe Giannini,Loris Bernard,Riccardo Dolcetti,Siranoush Manoukian,Norbert Arnold,Christoph Engel,Helmut Deissler,Kerstin Rhiem,Dieter Niederacher,Hansjoerg Plendl,Christian Sutter,Barbara Wappenschmidt,Åke Borg,Beatrice Melin,Johanna Rantala,Maria Soller,Katherine L. Nathanson,Susan M. Domchek,Gustavo C. Rodriguez,Ritu Salani,Daphne Gschwantler Kaulich,Muy Kheng Tea,Shani Shimon Paluch,Yael Laitman,Anne-Bine Skytte,Torben A Kruse,Uffe Birk Jensen,Mark E. Robson,Anne-Marie Gerdes,Bent Ejlertsen,Lenka Foretova,Sharon A. Savage,Jenny Lester,Penny Soucy,Karoline Kuchenbaecker,Curtis Olswold,Julie M. Cunningham,Susan L. Slager,Vernon S. Pankratz,Ed Dicks,Sunil R. Lakhani,Sunil R. Lakhani,Fergus J. Couch,Per Hall,Alvaro N.A. Monteiro,Simon A. Gayther,Paul D.P. Pharoah,Roger R. Reddel,Roger R. Reddel,Ellen L. Goode,Mark H. Greene,Douglas F. Easton,Andrew Berchuck,Antonis C. Antoniou,Georgia Chenevix-Trench,Alison M. Dunning +455 more
TL;DR: Using the Illumina custom genotyping array iCOGs, SNPs at the TERT locus in breast, ovarian and BRCA1 mutation carrier cancer cases and controls and leukocyte telomere measurements are analyzed to find associations cluster into three independent peaks.
Journal ArticleDOI
Genome-wide association studies identify four ER negative-specific breast cancer risk loci
Montserrat Garcia-Closas,Fergus J. Couch,Sara Lindström,Kyriaki Michailidou,Marjanka K. Schmidt,Mark N. Brook,Nick Orr,Suhn K. Rhie,Elio Riboli,Heather Spencer Feigelson,Loic Le Marchand,Julie E. Buring,Diana Eccles,Penelope Miron,Peter A. Fasching,Peter A. Fasching,Hiltrud Brauch,Hiltrud Brauch,Jenny Chang-Claude,Jane Carpenter,Andrew K. Godwin,Heli Nevanlinna,Graham G. Giles,Graham G. Giles,Angela Cox,John L. Hopper,Manjeet K. Bolla,Qin Wang,Joe Dennis,Ed Dicks,William J. Howat,Nils Schoof,Stig E. Bojesen,Stig E. Bojesen,Diether Lambrechts,Diether Lambrechts,Annegien Broeks,Irene L. Andrulis,Pascal Guénel,Pascal Guénel,Barbara Burwinkel,Barbara Burwinkel,Elinor J. Sawyer,Antoinette Hollestelle,Olivia Fletcher,Robert Winqvist,Hermann Brenner,Arto Mannermaa,Ute Hamann,Alfons Meindl,Annika Lindblom,Wei Zheng,Peter Devillee,Peter Devillee,Mark S. Goldberg,Jan Lubinski,Vessela N. Kristensen,Anthony J. Swerdlow,Hoda Anton-Culver,Thilo Dörk,Kenneth Muir,Kenneth Muir,Keitaro Matsuo,Anna H. Wu,Paolo Radice,Soo Hwang Teo,Xiao-Ou Shu,William Blot,Daehee Kang,Mikael Hartman,Suleeporn Sangrajrang,Chen-Yang Shen,Chen-Yang Shen,Melissa C. Southey,Daniel J. Park,Fleur Hammet,Jennifer Stone,Laura J. van't Veer,Emiel J. Th. Rutgers,Artitaya Lophatananon,Sarah Stewart-Brown,Pornthep Siriwanarangsan,Julian Peto,Michael G. Schrauder,Arif B. Ekici,Matthias W. Beckmann,Isabel dos Santos Silva,Nichola Johnson,Helen R. Warren,Ian Tomlinson,Michael J. Kerin,Nicola Miller,Federick Marme,Andreas Schneeweiss,Christof Sohn,Thérèse Truong,Thérèse Truong,Pierre Laurent-Puig,Pierre Kerbrat,Børge G. Nordestgaard,Sune F. Nielsen,Henrik Flyger,Roger L. Milne,Jose Ignacio Arias Perez,Primitiva Menéndez,Heiko Müller,Volker Arndt,Christa Stegmaier,Peter Lichtner,Magdalena Lochmann,Christina Justenhoven,Christina Justenhoven,Yon Ko,Taru A. Muranen,Kristiina Aittomäki,Carl Blomqvist,Dario Greco,Tuomas Heikkinen,Hidemi Ito,Hiroji Iwata,Yasushi Yatabe,Natalia Antonenkova,Sara Margolin,Vesa Kataja,Veli-Matti Kosma,Jaana M. Hartikainen,Rosemary L. Balleine,Chiu-Chen Tseng,David Van Den Berg,Daniel O. Stram,Patrick Neven,Anne Sophie Dieudonne,Karin Leunen,Anja Rudolph,Stefan Nickels,Dieter Flesch-Janys,Paolo Peterlongo,Bernard Peissel,Loris Bernard,Janet E. Olson,Xianshu Wang,Kristen N. Stevens,Gianluca Severi,Gianluca Severi,Laura Baglietto,Laura Baglietto,Catriona McLean,Gerhard A. Coetzee,Ye Feng,Brian E. Henderson,Fredrick R. Schumacher,Natalia Bogdanova,Martine Dumont,Cheng Har Yip,Nur Aishah Taib,Ching-Yu Cheng,Martha J. Shrubsole,Jirong Long,Katri Pylkäs,Arja Jukkola-Vuorinen,Saila Kauppila,Julia A. Knight,Gord Glendon,Anna Marie Mulligan,R.A.E.M. Tollenaar,Caroline M. Seynaeve,Mieke Kriege,Maartje J. Hooning,Ans M.W. van den Ouweland,Carolien H.M. van Deurzen,Wei Lu,Yu Tang Gao,Hui Cai,Sabapathy P. Balasubramanian,Simon S. Cross,Malcolm W.R. Reed,Lisa B. Signorello,Qiuyin Cai,Mitul Shah,Hui Miao,Ching Wan Chan,Kee Seng Chia,Anna Jakubowska,Katarzyna Jaworska,Katarzyna Durda,Chia-Ni Hsiung,Pei Ei Wu,Jyh Cherng Yu,Alan Ashworth,Michael Jones,Daniel C. Tessier,Anna González-Neira,Guillermo Pita,M. Rosario Alonso,Daniel Vincent,Francois Bacot,Christine B. Ambrosone,Elisa V. Bandera,Esther M. John,Esther M. John,Gary K. Chen,Jennifer J. Hu,Jorge L. Rodriguez-Gil,Leslie Bernstein,Michael F. Press,Regina G. Ziegler,Robert M. Millikan,Sandra Deming-Halverson,Sarah J. Nyante,Sue A. Ingles,Quinten Waisfisz,Helen Tsimiklis,Enes Makalic,Daniel F. Schmidt,Minh Bui,Lorna Gibson,Bertram Müller-Myhsok,Rita K. Schmutzler,Rebecca Hein,Rebecca Hein,Norbert Dahmen,Lars Beckmann,Kirsimari Aaltonen,Kamila Czene,Astrid Irwanto,Jianjun Liu,Clare Turnbull,Nazneen Rahman,Hanne Meijers-Heijboer,André G. Uitterlinden,Fernando Rivadeneira,Curtis Olswold,Susan L. Slager,Robert Pilarski,Foluso O. Ademuyiwa,Irene Konstantopoulou,Nicholas G. Martin,Grant W. Montgomery,Dennis J. Slamon,Claudia Rauh,Michael P. Lux,Sebastian M. Jud,Thomas Brüning,JoEllen Weaver,Priyanka Sharma,Harsh B. Pathak,William J. Tapper,Sue Gerty,Lorraine Durcan,Dimitrios Trichopoulos,Dimitrios Trichopoulos,Rosario Tumino,Petra H.M. Peeters,Rudolf Kaaks,Daniele Campa,Federico Canzian,Elisabete Weiderpass,Mattias Johansson,Kay-Tee Khaw,Ruth C. Travis,Françoise Clavel-Chapelon,Françoise Clavel-Chapelon,Laurence N. Kolonel,Constance Chen,Andrew H. Beck,Susan E. Hankinson,Susan E. Hankinson,Christine D. Berg,Robert N. Hoover,Jolanta Lissowska,Jonine D. Figueroa,Daniel I. Chasman,Mia M. Gaudet,W. Ryan Diver,Walter C. Willett,David J. Hunter,Jacques Simard,Javier Benitez,Alison M. Dunning,Mark E. Sherman,Georgia Chenevix-Trench,Stephen J. Chanock,Per Hall,Paul D.P. Pharoah,Celine M. Vachon,Douglas F. Easton,Christopher A. Haiman,Peter Kraft +287 more
TL;DR: SNPs at four loci were associated with ER-negative but not ER-positive breast cancer (P > 0.05), providing further evidence for distinct etiological pathways associated with invasive ER- positive and ER- negative breast cancers.
Journal ArticleDOI
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
Keri L. Monda,Keri L. Monda,Gary K. Chen,Kira C. Taylor,Kira C. Taylor,Cameron D. Palmer,Cameron D. Palmer,Todd L. Edwards,Leslie A. Lange,Maggie C.Y. Ng,Adebowale Adeyemo,Matthew A. Allison,Lawrence F. Bielak,Guanjie Chen,Mariaelisa Graff,Marguerite R. Irvin,Suhn K. Rhie,Guo Li,Yongmei Liu,Youfang Liu,Yingchang Lu,Mike A. Nalls,Yan V. Sun,Mary K. Wojczynski,Lisa R. Yanek,Melinda C. Aldrich,Adeyinka Ademola,Christopher I. Amos,Christopher I. Amos,Elisa V. Bandera,Cathryn H. Bock,Angela Britton,Ulrich Broeckel,Quiyin Cai,Neil E. Caporaso,Christopher S. Carlson,John D. Carpten,Graham Casey,Wei-Min Chen,Fang Chen,Yii-Der Ida Chen,Charleston W. K. Chiang,Gerhard A. Coetzee,Ellen W. Demerath,Sandra Deming-Halverson,Ryan W. Driver,Patricia M. Dubbert,Mary F. Feitosa,Ye Feng,Barry I. Freedman,Elizabeth M. Gillanders,Omri Gottesman,Xiuqing Guo,Talin Haritunians,Tamara B. Harris,Curtis C. Harris,Anselm Hennis,Dena G. Hernandez,Lorna H. McNeill,Timothy D. Howard,Barbara V. Howard,Barbara V. Howard,Virginia J. Howard,Karen C. Johnson,Sun J. Kang,Brendan J. Keating,Suzanne Kolb,Lewis H. Kuller,Abdullah Kutlar,Carl D. Langefeld,Guillaume Lettre,Kurt Lohman,Vaneet Lotay,Helen N. Lyon,JoAnn E. Manson,William Maixner,Yan A. Meng,Kristine R. Monroe,Imran O. Morhason-Bello,Adam B. Murphy,Josyf C. Mychaleckyj,Rajiv Nadukuru,Katherine L. Nathanson,Uma Nayak,Amidou N'Diaye,Barbara Nemesure,Suh Yuh Wu,M. Cristina Leske,Christine Neslund-Dudas,Marian L. Neuhouser,Sarah J. Nyante,Heather M. Ochs-Balcom,Adesola Ogunniyi,Temidayo O. Ogundiran,Oladosu Ojengbede,Olufunmilayo I. Olopade,Julie R. Palmer,Edward A. Ruiz-Narváez,Nicholette D. Palmer,Michael F. Press,Evandine Rampersaud,Laura J. Rasmussen-Torvik,Jorge L. Rodriguez-Gil,Babatunde L. Salako,Eric E. Schadt,Ann G. Schwartz,Daniel Shriner,David S. Siscovick,Shad B. Smith,Sylvia Wassertheil-Smoller,Elizabeth K. Speliotes,Elizabeth K. Speliotes,Elizabeth K. Speliotes,Margaret R. Spitz,Lara Sucheston,Herman A. Taylor,Bamidele O. Tayo,Margaret A. Tucker,David Van Den Berg,Digna R. Velez Edwards,Zhaoming Wang,John K. Wiencke,Thomas W. Winkler,Thomas W. Winkler,John S. Witte,Margaret Wrensch,Xifeng Wu,James J. Yang,Albert M. Levin,Taylor Young,Neil A. Zakai,Mary Cushman,Krista A. Zanetti,Jing Hua Zhao,Wei Zhao,Yonglan Zheng,Jie Zhou,Regina G. Ziegler,Joseph M. Zmuda,Jyotika K. Fernandes,Gary S. Gilkeson,Diane L. Kamen,Kelly J. Hunt,Ida J. Spruill,Christine B. Ambrosone,Stefan Ambs,Donna K. Arnett,Larry D. Atwood,Diane M. Becker,Sonja I. Berndt,Leslie Bernstein,William J. Blot,Ingrid B. Borecki,Erwin P. Bottinger,Donald W. Bowden,Gregory L. Burke,Stephen J. Chanock,Richard S. Cooper,Jingzhong Ding,David Duggan,Michele K. Evans,Caroline S. Fox,Caroline S. Fox,W. Timothy Garvey,Jonathan P. Bradfield,Hakon Hakonarson,Struan F.A. Grant,Ann W. Hsing,Ann W. Hsing,Lisa Chu,Jennifer J. Hu,Dezheng Huo,Sue A. Ingles,Esther M. John,Esther M. John,Joanne M. Jordan,Edmond K. Kabagambe,Sharon L.R. Kardia,Rick A. Kittles,Phyllis J. Goodman,Eric A. Klein,Laurence N. Kolonel,Loic Le Marchand,Simin Liu,Barbara McKnight,Robert C. Millikan,Thomas H. Mosley,Badri Padhukasahasram,L. Keoki Williams,Sanjay R. Patel,Ulrike Peters,Curtis A. Pettaway,Patricia A. Peyser,Bruce M. Psaty,Bruce M. Psaty,Susan Redline,Charles N. Rotimi,Benjamin A. Rybicki,Michèle M. Sale,Pamela J. Schreiner,Lisa B. Signorello,Andrew B. Singleton,Janet L. Stanford,Sara S. Strom,Michael J. Thun,Mara Z. Vitolins,Wei Zheng,Jason H. Moore,Scott M. Williams,Shamika Ketkar,Xiaofeng Zhu,Alan B. Zonderman,Charles Kooperberg,George J. Papanicolaou,Brian E. Henderson,Alexander P. Reiner,Joel N. Hirschhorn,Joel N. Hirschhorn,Ruth J. F. Loos,Ruth J. F. Loos,Kari E. North,Christopher A. Haiman +221 more
TL;DR: A meta-analysis to examine the association of >3.2 million SNPs with BMI in 39,144 men and women of African ancestry and followed up the most significant associations in an additional 32,268 individuals ofAfrican ancestry provides strong support for shared BMI loci across populations, as well as for the utility of studying ancestrally diverse populations.