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Christina Willenborg
Researcher at University of Tampere
Publications - 5
Citations - 164
Christina Willenborg is an academic researcher from University of Tampere. The author has contributed to research in topics: Odds ratio & Gene. The author has an hindex of 3, co-authored 5 publications receiving 136 citations. Previous affiliations of Christina Willenborg include Wake Forest University & University of Kiel.
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Journal ArticleDOI
Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease
Sujoy Ghosh,Juan C. Vivar,Christopher P. Nelson,Christina Willenborg,Ayellet V. Segrè,Ville-Petteri Mäkinen,Majid Nikpay,J Erdmann,Stefan Blankenberg,Christopher J. O'Donnell,Winfried März,Reijo Laaksonen,Alexandre F.R. Stewart,Stephen E. Epstein,Svati H. Shah,Christopher B. Granger,Stanley L. Hazen,Sekar Kathiresan,Muredach P. Reilly,Xia Yang,Thomas Quertermous,Nilesh J. Samani,Heribert Schunkert,Themistocles L. Assimes,Ruth McPherson +24 more
TL;DR: Findings provide novel insights into how genetic variation, interpreted in the context of biological processes and functional interactions among genes, may help define the genetic architecture of CAD.
Journal ArticleDOI
Psoriasis and Cardiometabolic Traits: Modest Association but Distinct Genetic Architectures
Manja Koch,Hansjörg Baurecht,Janina S. Ried,Elke Rodriguez,Sabrina Schlesinger,Natalie Volks,Christian Gieger,Ina Maria Rückert,L Heinrich,Christina Willenborg,Catherine H. Smith,Annette Peters,Barbara Thorand,Wolfgang Koenig,Claudia Lamina,Henning Jansen,Florian Kronenberg,Jochen Seissler,Joachim Thiery,Wolfgang Rathmann,Heribert Schunkert,Jeanette Erdmann,Jonathan Barker,Rajan P. Nair,Lam C. Tsoi,James T. Elder,James T. Elder,Ulrich Mrowietz,Michael Weichenthal,Sören Mucha,Stefan Schreiber,Andre Franke,Jochen Schmitt,Wolfgang Lieb,Stephan Weidinger +34 more
TL;DR: It is suggested that severe psoriasis, in particular severe psOriasis, increases risk for T2D and MI, and that the genetic architecture of ps oriasis and cardiometabolic traits is largely distinct.
Journal ArticleDOI
Loss of cardioprotective effects at the ADAMTS7 locus as a result of gene-smoking interactions
Danish Saleheen,Wei Zhao,Robin Young,Christopher P. Nelson,WeangKee Ho,Jane F. Ferguson,Jane F. Ferguson,Asif Rasheed,Kristy Ou,Sylvia T. Nurnberg,Sylvia T. Nurnberg,Robert C. Bauer,Robert C. Bauer,Anuj Goel,Ron Do,Ron Do,Alexandre F.R. Stewart,Alexandre F.R. Stewart,Jaana Hartiala,Jaana Hartiala,Weihua Zhang,Gudmar Thorleifsson,Rona J. Strawbridge,Rona J. Strawbridge,Juha Sinisalo,Stavroula Kanoni,Stavroula Kanoni,Sanaz Sedaghat,Eirini Marouli,Eirini Marouli,K. Kristiansson,K. Kristiansson,Jing Hua Zhao,Jing Hua Zhao,Robert A. Scott,Dominique Gauguier,Dominique Gauguier,Svati H. Shah,Svati H. Shah,Albert V. Smith,Natalie van Zuydam,Amanda J. Cox,Christina Willenborg,Christina Willenborg,Christina Willenborg,Thorsten Kessler,Lingyao Zeng,Michael A. Province,Andrea Ganna,Lars Lind,Nancy L. Pedersen,Charles C. White,Anni Joensuu,Marcus Edi Kleber,Alistair S. Hall,Winfried März,Veikko Salomaa,Christopher J. O'Donnell,Erik Ingelsson,Mary F. Feitosa,Jeanette Erdmann,Donald W. Bowden,Donald W. Bowden,Colin N. A. Palmer,Colin N. A. Palmer,Vilmundur Gudnason,Ulf de Faire,Pierre Zalloua,Nicholas J. Wareham,John Thompson,Kari Kuulasmaa,George V. Dedoussis,George V. Dedoussis,Markus Perola,Abbas Dehghan,John C. Chambers,John C. Chambers,Jaspal S. Kooner,Hooman Allayee,Panos Deloukas,Ruth McPherson,Ruth McPherson,K. Stefansson,Heribert Schunkert,Sekar Kathiresan,Sekar Kathiresan,Martin Farrall,Philippe M. Frossard,Daniel J. Rader,Nilesh J. Samani,Muredach P. Reilly +90 more
TL;DR: In this paper, the interaction of genetic susceptibility with lifestyle factors may play a prominent role in coronary heart disease (CHD) etiology and the interaction between genetic susceptibility and lifestyle factors is discussed.
Journal ArticleDOI
Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood
Yan Zheng,Tao Huang,Tiange Wang,Tiange Wang,Zhendong Mei,Zhonghan Sun,Tao Zhang,Tao Zhang,Christina Ellervik,Jin-Fang Chai,Xueling Sim,Rob M. van Dam,E-Shyong Tai,Woon-Puay Koh,Rajkumar Dorajoo,Seang-Mei Saw,Charumathi Sabanayagam,Tien Yin Wong,Preeti Gupta,Peter Rossing,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Rebecca K. Vinding,Hans Bisgaard,Klaus Bønnelykke,Yujie Wang,Mariaelisa Graff,Trudy Voortman,Frank J. A. van Rooij,Albert Hofman,Albert Hofman,Diana van Heemst,Raymond Noordam,Angela C. Estampador,Tibor V. Varga,Cornelia Enzenbach,Markus Scholz,Joachim Thiery,Ralph Burkhardt,Ralph Burkhardt,Marju Orho-Melander,Christina-Alexandra Schulz,Ulrika Ericson,Emily Sonestedt,Michiaki Kubo,Masato Akiyama,Ang Zhou,Tuomas O. Kilpeläinen,Torben Hansen,Marcus E. Kleber,Marcus E. Kleber,Graciela E. Delgado,Mark I. McCarthy,Rozenn N. Lemaitre,Janine F. Felix,Vincent W. V. Jaddoe,Ying Wu,Karen L. Mohlke,Terho Lehtimäki,Carol A. Wang,Craig E. Pennell,Heribert Schunkert,Thorsten Kessler,Lingyao Zeng,Christina Willenborg,Annette Peters,Wolfgang Lieb,Veit Grote,Peter Rzehak,Berthold Koletzko,Jeanette Erdmann,Matthias Munz,Matthias Munz,Tangchun Wu,Meian He,Caizheng Yu,Cécile Lecoeur,Cécile Lecoeur,Philippe Froguel,Philippe Froguel,Dolores Corella,Dolores Corella,Luis A. Moreno,Luis A. Moreno,Chao-Qiang Lai,Niina Pitkänen,Colin Boreham,Paul M. Ridker,Frits R. Rosendaal,Renée de Mutsert,Chris Power,Lavinia Paternoster,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Anne Tjønneland,Kim Overvad,Kim Overvad,Luc Djoussé,Fernando Rivadeneira,Nanette R. Lee,Olli T. Raitakari,Olli T. Raitakari,Mika Kähönen,Jorma Viikari,Jorma Viikari,Jean-Paul Langhendries,Joaquin Escribano,Elvira Verduci,George Dedoussis,Inke R. König,Beverley Balkau,Oscar Coltell,Oscar Coltell,Jean Dallongeville,Aline Meirhaeghe,Philippe Amouyel,Frédéric Gottrand,Katja Pahkala,Katja Pahkala,Harri Niinikoski,Harri Niinikoski,Elina Hyppönen,Elina Hyppönen,Winfried März,Winfried März,Winfried März,David A. Mackey,Dariusz Gruszfeld,Katherine L. Tucker,Frédéric Fumeron,Frédéric Fumeron,Ramon Estruch,Jose M. Ordovas,Jose M. Ordovas,Donna K. Arnett,Dennis O. Mook-Kanamori,Dariush Mozaffarian,Bruce M. Psaty,Kari E. North,Daniel I. Chasman,Lu Qi +141 more
TL;DR: The findings suggest that the inverse association of birthweight with hypertension risk from observational studies was not supported by large Mendelian randomization analyses.