C
Claudio Scazzocchio
Researcher at Imperial College London
Publications - 184
Citations - 10974
Claudio Scazzocchio is an academic researcher from Imperial College London. The author has contributed to research in topics: Aspergillus nidulans & Gene. The author has an hindex of 50, co-authored 180 publications receiving 10389 citations. Previous affiliations of Claudio Scazzocchio include Université Paris-Saclay & University of Paris-Sud.
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Journal ArticleDOI
Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae
James E. Galagan,Sarah E. Calvo,Christina A. Cuomo,Li-Jun Ma,Jennifer R. Wortman,Serafim Batzoglou,Su-In Lee,Meray Baştürkmen,Christina C. Spevak,John Clutterbuck,Vladimir V. Kapitonov,Jerzy Jurka,Claudio Scazzocchio,Mark L. Farman,Jonathan Butler,Seth Purcell,Steve Harris,Gerhard H. Braus,Oliver W. Draht,Silke Busch,Christophe d'Enfert,Christiane Bouchier,Gustavo H. Goldman,Deborah Bell-Pedersen,Sam Griffiths-Jones,John H. Doonan,Jae-Hyuk Yu,Kay Vienken,Arnab Pain,Michael Freitag,Eric U. Selker,David B. Archer,Miguel A. Peñalva,Berl R. Oakley,Michelle Momany,Toshihiro Tanaka,Toshitaka Kumagai,Kiyoshi Asai,Masayuki Machida,William C. Nierman,David W. Denning,Mark X. Caddick,Michael J. Hynes,Mathieu Paoletti,Reinhard Fischer,Reinhard Fischer,Bruce L. Miller,Paul S. Dyer,Matthew S. Sachs,Stephen A. Osmani,Bruce W. Birren +50 more
TL;DR: The aspergilli comprise a diverse group of filamentous fungi spanning over 200 million years of evolution, and a comparative study with Aspergillus fumigatus and As pergillus oryzae, used in the production of sake, miso and soy sauce, provides new insight into eukaryotic genome evolution and gene regulation.
Journal ArticleDOI
Double-joint PCR: a PCR-based molecular tool for gene manipulations in filamentous fungi.
Jae-Hyuk Yu,Zsuzsanna Hamari,Kap Hoon Han,Jeong-Ah Seo,Yazmid Reyes-Dominguez,Claudio Scazzocchio,Claudio Scazzocchio +6 more
TL;DR: A PCR-assisted DNA assembly procedure is developed and applied to delete 31 genes in filamentous fungi and was effectively used to fuse more than 10 genes to a controllable promoter.
Journal ArticleDOI
Transformation by integration in Aspergillus nidulans.
J Tilburn,Claudio Scazzocchio,Graham G. Taylor,J H Zabicky-Zissman,Robin A. Lockington,R.W. Davies +5 more
TL;DR: DNA-mediated genetic transformation of Aspergillus nidulans has been achieved by incubating protoplasts from a strain of A. niduans carrying a deletion in the acetamidase structural gene with DNA of derivatives of plasmid pBR322 containing the cloned structural gene for acetamids.
Journal ArticleDOI
Making ends meet: a model for RNA splicing in fungal mitochondria
TL;DR: A model for RNA splicing in fungal mitochondria is presented, involving four conserved sequences that bring the ends of each intron together and allow an internal guide RNA sequence to pair with exon bases adjacent to the splice junctions.
Journal ArticleDOI
Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus
Ronald P. de Vries,Robert Riley,Ad Wiebenga,Guillermo Aguilar-Osorio,Sotiris Amillis,Cristiane Uchima,Gregor Anderluh,Mojtaba Asadollahi,Marion Askin,Marion Askin,Kerrie Barry,Evy Battaglia,Özgür Bayram,Özgür Bayram,Tiziano Benocci,Susanna A. Braus-Stromeyer,Camila Caldana,David Cánovas,David Cánovas,Gustavo C. Cerqueira,Fusheng Chen,Wanping Chen,Cindy Choi,Alicia Clum,Renato Augusto Corrêa dos Santos,André Damasio,George Diallinas,Tamás Emri,Erzsébet Fekete,Michel Flipphi,Susanne Freyberg,Antonia Gallo,Christos Gournas,Rob Habgood,Matthieu Hainaut,María Harispe,Bernard Henrissat,Bernard Henrissat,Bernard Henrissat,Kristiina Hildén,Ryan Hope,Abeer Hossain,Eugenia Karabika,Eugenia Karabika,Levente Karaffa,Zsolt Karányi,Nada Kraševec,Alan Kuo,Harald Kusch,Kurt LaButti,Ellen Lagendijk,Alla Lapidus,Alla Lapidus,Anthony Levasseur,Erika Lindquist,Anna Lipzen,Antonio F. Logrieco,Andrew MacCabe,Miia R. Mäkelä,Iran Malavazi,Petter Melin,Vera Meyer,Natalia Mielnichuk,Natalia Mielnichuk,Márton Miskei,Ákos Molnár,Giuseppina Mulè,Chew Yee Ngan,Margarita Orejas,Erzsébet Orosz,Erzsébet Orosz,Jean Paul Ouedraogo,Jean Paul Ouedraogo,Karin M. Overkamp,Hee-Soo Park,Giancarlo Perrone,François Piumi,François Piumi,Peter J. Punt,Arthur F. J. Ram,Ana Ramón,Stefan Rauscher,Eric Record,Diego Mauricio Riaño-Pachón,Vincent Robert,Julian Röhrig,Roberto Ruller,Asaf Salamov,Nadhira Salih,Nadhira Salih,Rob Samson,Erzsébet Sándor,Manuel Sanguinetti,Tabea Schütze,Tabea Schütze,Kristina Sepčić,Ekaterina Shelest,Gavin Sherlock,Vicky Sophianopoulou,Fabio M. Squina,Hui Sun,Antonia Susca,Richard B. Todd,Adrian Tsang,Shiela E. Unkles,Nathalie van de Wiele,Diana van Rossen-Uffink,Juliana Velasco de Castro Oliveira,Tammi Camilla Vesth,Jaap Visser,Jae-Hyuk Yu,Miaomiao Zhou,Mikael Rørdam Andersen,David B. Archer,Scott E. Baker,Isabelle Benoit,Isabelle Benoit,Axel A. Brakhage,Gerhard H. Braus,Reinhard Fischer,Jens Christian Frisvad,Gustavo H. Goldman,Jos Houbraken,Berl R. Oakley,István Pócsi,Claudio Scazzocchio,Claudio Scazzocchio,Bernhard Seiboth,Patricia A. vanKuyk,Patricia A. vanKuyk,Jennifer R. Wortman,Paul S. Dyer,Igor V. Grigoriev +132 more
TL;DR: In this article, a comparative genomics and experimental study of the aspergilli genus is presented, which allows for the first time a genus-wide view of the biological diversity of the Aspergillus and in many, but not all, cases linked genome differences to phenotype.