E
Eva Harris
Researcher at University of California, Berkeley
Publications - 357
Citations - 26475
Eva Harris is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Dengue virus & Dengue fever. The author has an hindex of 84, co-authored 332 publications receiving 22718 citations.
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Journal ArticleDOI
Global spread and persistence of dengue.
Jennifer L. Kyle,Eva Harris +1 more
TL;DR: This review explores the human, mosquito, and viral factors that contribute to the global spread and persistence of dengue, as well as the interaction between the three spheres, in the context of ecological and climate changes.
Journal ArticleDOI
Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis
Harish Nair,Harish Nair,W. Abdullah Brooks,Mark A. Katz,Anna Roca,James A. Berkley,Shabir A. Madhi,James Mark Simmerman,Aubree Gordon,Aubree Gordon,Masatoki Sato,Stephen R. C. Howie,Anand Krishnan,Maurice Ope,Kim A. Lindblade,Phyllis Carosone-Link,Marilla G. Lucero,Walter Onalo Ochieng,Laurie Kamimoto,Erica Dueger,Niranjan Bhat,Sirenda Vong,Evropi Theodoratou,Malinee Chittaganpitch,Osaretin Chimah,Osaretin Chimah,Angel Balmaseda,Philippe Buchy,Eva Harris,Valerie Evans,Masahiko Katayose,Bharti Gaur,Cristina O'Callaghan-Gordo,Doli Goswami,Wences Arvelo,Marietjie Venter,Thomas Briese,Rafal Tokarz,Marc-Alain Widdowson,Anthony W. Mounts,Robert F. Breiman,Daniel R. Feikin,Daniel R. Feikin,Keith P. Klugman,Keith P. Klugman,Sonja J. Olsen,Bradford D. Gessner,Peter F. Wright,Igor Rudan,Igor Rudan,Shobha Broor,Eric A. F. Simões,Harry Campbell +52 more
TL;DR: The role of influenza in childhood mortality from ALRI is estimated by combining incidence estimates with case fatality ratios from hospital-based reports and identifying studies with population-based data for influenza seasonality and monthly ALRI mortality.
Journal ArticleDOI
Antibody-dependent enhancement of severe dengue disease in humans
Leah C. Katzelnick,Lionel Gresh,M. Elizabeth Halloran,M. Elizabeth Halloran,Juan Carlos Mercado,Guillermina Kuan,Aubree Gordon,Angel Balmaseda,Eva Harris +8 more
TL;DR: Using multiple statistical approaches to study a long-term pediatric cohort in Nicaragua, it is shown that risk of severe dengue disease is highest within a narrow range of preexisting anti-DENV antibody titers, which has major implications for vaccines against flaviviruses.
Journal ArticleDOI
Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection
Karin Stettler,Martina Beltramello,Diego A. Espinosa,Victoria A. Graham,Antonino Cassotta,Antonino Cassotta,Siro Bianchi,Fabrizia Vanzetta,Andrea Minola,Stefano Jaconi,Federico Mele,Mathilde Foglierini,Mattia Pedotti,Luca Simonelli,Stuart D. Dowall,Barry Atkinson,Elena Percivalle,Cameron P. Simmons,Cameron P. Simmons,Luca Varani,Johannes Blum,Johannes Blum,Fausto Baldanti,Elisabetta Cameroni,Roger Hewson,Eva Harris,Antonio Lanzavecchia,Antonio Lanzavecchia,Federica Sallusto,Davide Corti +29 more
TL;DR: The most potent neutralizing antibodies were ZIKV-specific and targeted EDIII or quaternary epitopes on infectious virus, and an EDIII-targeted antibody protected mice against lethal infection, illustrating the potential for antibody-based therapy.
Journal ArticleDOI
The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing Activity
Martina Beltramello,Katherine L. Williams,Cameron P. Simmons,Annalisa Macagno,Luca Simonelli,Nguyen Than Ha Quyen,Soila Sukupolvi-Petty,Erika Navarro-Sanchez,Paul R. Young,Aravinda M. de Silva,Félix A. Rey,Luca Varani,Stephen S. Whitehead,Michael S. Diamond,Eva Harris,Antonio Lanzavecchia,Federica Sallusto +16 more
TL;DR: These findings reveal an unexpected degree of cross-reactivity in human antibodies against DENV and illustrate the potential for an antibody-based therapy to control severe dengue.