M
Margi Sheth
Researcher at National Institutes of Health
Publications - 34
Citations - 77059
Margi Sheth is an academic researcher from National Institutes of Health. The author has contributed to research in topics: DNA methylation & Gene. The author has an hindex of 32, co-authored 34 publications receiving 61560 citations.
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Journal ArticleDOI
Comprehensivemolecular characterization of clear cell renal cell carcinoma
Chad J. Creighton,Margaret Morgan,Preethi H. Gunaratne,Preethi H. Gunaratne,David A. Wheeler,Richard A. Gibbs,Gordon Robertson,Andy Chu,Rameen Beroukhim,Kristian Cibulskis,Sabina Signoretti,Fabio Vandin,Hsin-Ta Wu,Benjamin J. Raphael,Roel G.W. Verhaak,Pheroze Tamboli,Wandaliz Torres-Garcia,Rehan Akbani,John N. Weinstein,Victor E. Reuter,James J. Hsieh,A. Rose Brannon,A. Ari Hakimi,Anders Jacobsen,Giovanni Ciriello,Boris Reva,Christopher J. Ricketts,W. Marston Linehan,Joshua M. Stuart,W. Kimryn Rathmell,Shen Hui,Peter W. Laird,Donna M. Muzny,Caleb F. Davis,Xi Liu,Kyle Chang,Nipun Kakkar,Lisa R. Trevino,Susan M. Benton,Jeffrey G. Reid,Donna Morton,Harsha Doddapaneni,Han Yi,Lora Lewis,Dinh Huyen,Christie Kovar,Yiming Zhu,Jireh Santibanez,Wang Min,Walker Hale,Divya Kalra,Gad Getz,Michael S. Lawrence,Carrie Sougnez,Scott L. Carter,Andrey Sivachenko,Lichtenstein Lee,Chip Stewart,Doug Voet,Sheila Fisher,Stacey Gabriel,Eric S. Lander,Steve Schumacher,Barbara Tabak,Gordon Saksena,Robert C. Onofrio,Andrew D. Cherniack,Jeff Gentry,Kristin G. Ardlie,Matthew Meyerson,Hye Jung E. Chun,Andrew J. Mungall,Payal Sipahimalani,Dominik Stoll,Adrian Ally,Miruna Balasundaram,Yaron S.N. Butterfield,Rebecca Carlsen,Candace Carter,Eric Chuah,Robin J.N. Coope,Noreen Dhalla,Sharon M. Gorski,Ranabir Guin,Carrie Hirst,Martin Hirst,Robert A. Holt,Chandra Lebovitz,Darlene Lee,Haiyan I. Li,Michael Mayo,Richard A. Moore,Erin Pleasance,Patrick Plettner,Jacqueline E. Schein,Arash Shafiei,Jared R. Slobodan,Angela Tam,Nina Thiessen,Richard Varhol,Natasja Wye,Yongjun Zhao,Inanc Birol,Steven J.M. Jones,Marco A. Marra,J. Todd Auman,Donghui Tan,Corbin D. Jones,Katherine A. Hoadley,Piotr A. Mieczkowski,Lisle E. Mose,Stuart R. Jefferys,Michael D. Topal,Christina Liquori,Yidi J. Turman,Shi Yan,Scot Waring,Elizabeth Buda,Jesse Walsh,Junyuan Wu,Tom Bodenheimer,Alan P. Hoyle,Janae V. Simons,Mathew G. Soloway,Saianand Balu,Joel S. Parker,D. Neil Hayes,Charles M. Perou,Raju Kucherlapati,Peter J. Park,Timothy J. Triche,Daniel J. Weisenberger,Phillip H. Lai,Moiz S. Bootwalla,Dennis T. Maglinte,Swapna Mahurkar,Benjamin P. Berman,David Van Den Berg,Leslie Cope,Stephen B. Baylin,Michael S. Noble,Daniel DiCara,Hailei Zhang,Juok Cho,David I. Heiman,Nils Gehlenborg,William Mallard,Lin Pei,Scott Frazer,Petar Stojanov,Yingchun Liu,Lihua Zhou,Jaegil Kim,Lynda Chin,Lynda Chin,Christopher C. Benz,Christina Yau,Sheila Reynolds,Ilya Shmulevich,Rahul Vegesna,Hoon Kim,Zhang Wei,David Cogdell,Eric Jonasch,Zhiyong Ding,Yiling Lu,Nianxiang Zhang,Anna K. Unruh,Tod D. Casasent,Chris Wakefield,Dimitra Tsavachidou,Gordon B. Mills,Jianjiong Gao,Ethan Cerami,Benjamin Gross,B. Arman Aksoy,Rileen Sinha,Nils Weinhold,S. Onur Sumer,Barry S. Taylor,Ronglai Shen,Irina Ostrovnaya,Michael F. Berger,Marc Ladanyi,Chris Sander,Suzanne S. Fei,Andrew J. Stout,Paul T. Spellman,Daniel L. Rubin,Tiffany Ting Liu,Ng Sam,Evan O. Paull,Daniel E. Carlin,Theodore C. Goldstein,Peter Waltman,Kyle Ellrott,Zhu Jing,David Haussler,Weimin Xiao,Candace Shelton,Johanna Gardner,Robert Penny,Mark E. Sherman,David Mallery,Scott Morris,Joseph Paulauskis,Ken Burnett,Troy Shelton,William G. Kaelin,William G. Kaelin,Toni K. Choueiri,Michael B. Atkins,Erin Curley,Satish K. Tickoo,Leigh B. Thorne,Lori Boice,Huang Mei,Jennifer C. Fisher,Cathy D. Vocke,James Peterson,Robert Worrell,Maria J. Merino,Laura S. Schmidt,Laura S. Schmidt,Bogdan Czerniak,Kenneth Aldape,Christopher G. Wood,Jeff Boyd,Jo Ellen Weaver,Mary Iacocca,Nicholas J. Petrelli,Gary Witkin,Jennifer Brown,Christine Czerwinski,Lori Huelsenbeck-Dill,Brenda Rabeno,Jerome Myers,Carl Morrison,Julie Bergsten,John Eckman,Jodi Harr,Christine I. Smith,Kelinda Tucker,Leigh Anne Zach,Wiam Bshara,Carmelo Gaudioso,Rajiv Dhir,Jodi K. Maranchie,Joel B. Nelson,Anil V. Parwani,Cureline Olga Potapova,Konstantin V. Fedosenko,John C. Cheville,R. Houston Thompson,Juan M. Mosquera,Mark A. Rubin,Michael L. Blute,Todd Pihl,Mark A. Jensen,Robert Sfeir,Ari B. Kahn,Anna Chu,Prachi Kothiyal,Eric E. Snyder,Joan Pontius,Brenda Ayala,Mark Backus,Jessica Walton,Julien Baboud,Dominique L. Berton,Matthew C. Nicholls,Deepak Srinivasan,Rohini Raman,Stanley Girshik,Peter A. Kigonya,Shelley Alonso,Rashmi N. Sanbhadti,Sean P. Barletta,David Pot,Margi Sheth,John A. Demchok,Tanja Davidsen,Zhining Wang,Liming Yang,Roy Tarnuzzer,Jiashan Zhang,Greg Eley,Martin L. Ferguson,Kenna R. Mills Shaw,Mark S. Guyer,Bradley A. Ozenberger,Heidi J. Sofia +291 more
TL;DR: Remodelling cellular metabolism constitutes a recurrent pattern in ccRCC that correlates with tumour stage and severity and offers new views on the opportunities for disease treatment.
Integrated genomic characterization of endometrial carcinoma
Gad Getz,Stacey Gabriel,Kristian Cibulskis,Eric S. Lander,Andrey Sivachenko,Carrie Sougnez,Michael S. Lawrence,Cyriac Kandoth,David J. Dooling,Robert S. Fulton,Lucinda Fulton,Joelle Kalicki-Veizer,Michael D. McLellan,Michelle O'Laughlin,Heather Schmidt,Richard K. Wilson,Kai Ye,Li Ding,Elaine R. Mardis,Adrian Ally,Miruna Balasundaram,Inanc Birol,Yaron S. Butterfield,Rebecca Carlsen,Candace D. Carter,Andy Chu,Eric Chuah,Hye Jung E. Chun,Noreen Dhalla,Ranabir Guin,Carrie Hirst,Robert A. Holt,Steven J.M. Jones,Darlene Lee,Haiyan I. Li,Marco A. Marra,Michael Mayo,Richard A. Moore,Andrew J. Mungall,Patrick Plettner,Jacqueline E. Schein,Payal Sipahimalani,Angela Tam,Richard Varhol,A. Gordon Robertson,Andrew D. Cherniack,Itai Pashtan,Gordon Saksena,Robert C. Onofrio,Steven E. Schumacher,Barbara Tabak,Scott L. Carter,Bryan Hernandez,Jeff Gentry,Helga B. Salvesen,Kristin Ardlie,Wendy Winckler,Rameen Beroukhim,Matthew Meyerson,Angela Hadjipanayis,Semin Lee,Harshad S. Mahadeshwar,Peter J. Park,Alexei Protopopov,Xiaojia Ren,Sahil Seth,Xingzhi Song,Jiabin Tang,Ruibin Xi,Lixing Yang,Dong Zeng,Raju Kucherlapati,Lynda Chin,Jianhua Zhang,J. Todd Auman,Saianand Balu,Tom Bodenheimer,Elizabeth Buda,D. Neil Hayes,Alan P. Hoyle,Stuart R. Jefferys,Corbin D. Jones,Shaowu Meng,Piotr A. Mieczkowski,Lisle E. Mose,Joel S. Parker,Charles M. Perou,Jeff Roach,Yan Shi,Janae V. Simons,Mathew G. Soloway,Donghui Tan,Michael D. Topal,Scot Waring,Junyuan Wu,Katherine A. Hoadley,Stephen B. Baylin,Moiz S. Bootwalla,Phillip H. Lai,Timothy J. Triche,David Van Den Berg,Daniel J. Weisenberger,Peter W. Laird,Hui Shen,Juok Cho,Daniel DiCara,Scott Frazer,David I. Heiman,Rui Jing,Pei Lin,Will Mallard,Petar Stojanov,Doug Voet,Hailei Zhang,Lihua Zou,Michael S. Noble,Sheila M. Reynolds,Ilya Shmulevich,B. Arman Aksoy,Yevgeniy Antipin,Giovanni Ciriello,Gideon Dresdner,Jianjiong Gao,Benjamin Gross,Anders Jacobsen,Marc Ladanyi,Boris Reva,Chris Sander,Rileen Sinha,S. Onur Sumer,Barry S. Taylor,Ethan Cerami,Nils Weinhold,Nikolaus Schultz,Ronglai Shen,Stephen C. Benz,Theodore C. Goldstein,David Haussler,Sam Ng,Christopher Szeto,Joshua M. Stuart,Christopher C. Benz,Christina Yau,Wei Zhang,Matti Annala,Bradley M. Broom,Tod D. Casasent,Zhenlin Ju,Han Liang,Guoyan Liu,Yiling Lu,Anna K. Unruh,Chris Wakefield,John N. Weinstein,Nianxiang Zhang,Yuexin Liu,Russell Broaddus,Rehan Akbani,Gordon B. Mills,Christopher Adams,Thomas Barr,Aaron D. Black,Jay Bowen,John Deardurff,Jessica Frick,Julie M. Gastier-Foster,Thomas Grossman,Hollie A. Harper,Melissa Hart-Kothari,Carmen Helsel,Aaron Hobensack,Harkness Kuck,Kelley Kneile,Kristen M. Leraas,Tara M. Lichtenberg,Cynthia McAllister,Robert E. Pyatt,Nilsa C. Ramirez,Teresa R. Tabler,Nathan Vanhoose,Peter White,Lisa Wise,Erik Zmuda,Nandita Barnabas,Charlenia Berry-Green,Victoria Blanc,Lori Boice,Michael Button,Adam M. Farkas,Alexander A. Green,Jean MacKenzie,Dana Nicholson,Steve E. Kalloger,C Blake Gilks,Beth Y. Karlan,Jenny Lester,Sandra Orsulic,Mark L. Borowsky,Mark G. Cadungog,Christine Czerwinski,Lori Huelsenbeck-Dill,Mary Iacocca,Nicholas J. Petrelli,Brenda Rabeno,Gary Witkin,Elena Nemirovich-Danchenko,Olga Potapova,D L Rotin,Andrew Berchuck,Michael J. Birrer,P.J. DiSaia,Laura Monovich,Erin Curley,Johanna Gardner,David Mallery,Robert Penny,Sean C. Dowdy,Boris Winterhoff,Linda Dao,Bobbie S. Gostout,Alexandra Meuter,Attila Teoman,Fanny Dao,Narciso Olvera,Faina Bogomolniy,Karuna Garg,Robert A. Soslow,Douglas A. Levine,Mikhail Abramov,John M. S. Bartlett,Sugy Kodeeswaran,Jeremy Parfitt,Fedor Moiseenko,Blaise A. Clarke,Marc T. Goodman,Michael E. Carney,Rayna K. Matsuno,Jennifer C. Fisher,Mei Huang,W. Kimryn Rathmell,Leigh B. Thorne,Linda Van Le,Rajiv Dhir,Robert R. Edwards,Esther Elishaev,Kristin K. Zorn,Paul J. Goodfellow,David G. Mutch,Ari B. Kahn,Daphne W. Bell,Pamela M. Pollock,Chen Wang,David A. Wheeler,Eve Shinbrot,Brenda Ayala,Anna L. Chu,Mark A. Jensen,Prachi Kothiyal,Todd Pihl,Joan Pontius,David A. Pot,Eric E. Snyder,Deepak Srinivasan,Kenna R. Mills Shaw,Margi Sheth,Tanja Davidsen,Greg Eley Martin L. Ferguson,John A. Demchok,Liming Yang,Mark S. Guyer,Bradley A. Ozenberger,Heidi J. Sofia +271 more
TL;DR: The genomic features of endometrial carcinomas permit a reclassification that may affect post-surgical adjuvant treatment for women with aggressive tumours, and these features are classified into four categories: POLE ultramutated, microsatellite instability hypermutated, copy- number low, and copy-number high.
Journal ArticleDOI
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.
Daniel J. Brat,Roel G.W. Verhaak,Kenneth Aldape,W. K. Alfred Yung,Sofie R. Salama,Lee Cooper,Esther Rheinbay,C. Ryan Miller,Mark Vitucci,Olena Morozova,A. Gordon Robertson,Houtan Noushmehr,Peter W. Laird,Andrew D. Cherniack,Rehan Akbani,Jason T. Huse,Giovanni Ciriello,Laila M. Poisson,Jill S. Barnholtz-Sloan,Mitchel S. Berger,Cameron Brennan,Rivka R. Colen,Howard Colman,Adam E. Flanders,Caterina Giannini,Mia Grifford,Antonio Iavarone,Rajan Jain,Isaac Joseph,Jaegil Kim,Katayoon Kasaian,Tom Mikkelsen,Bradley A. Murray,Brian P. O'Neill,Lior Pachter,Donald W. Parsons,Carrie Sougnez,Erik P. Sulman,Scott R. VandenBerg,Erwin G. Van Meir,Andreas von Deimling,Hailei Zhang,Daniel Crain,Kevin Lau,David Mallery,Scott Morris,Joseph Paulauskis,Robert Penny,Troy Shelton,Mark E. Sherman,Peggy Yena,Aaron D. Black,Jay Bowen,Katie Dicostanzo,Julie M. Gastier-Foster,Kristen M. Leraas,Tara M. Lichtenberg,Christopher R. Pierson,Nilsa C. Ramirez,Cynthia Taylor,Stephanie Weaver,Lisa Wise,Erik Zmuda,Tanja M. Davidsen,John A. Demchok,Greg Eley,Martin L. Ferguson,Carolyn M. Hutter,Kenna R. Mills Shaw,Bradley A. Ozenberger,Margi Sheth,Heidi J. Sofia,Roy Tarnuzzer,Zhining Wang,Liming Yang,Jean C. Zenklusen,Brenda Ayala,Julien Baboud,Sudha Chudamani,Mark A. Jensen,Jia Liu,Todd Pihl,Rohini Raman,Yunhu Wan,Ye Wu,Adrian Ally,J. Todd Auman,Miruna Balasundaram,Saianand Balu,Stephen B. Baylin,Rameen Beroukhim,Moiz S. Bootwalla,Reanne Bowlby,Christopher A. Bristow,Denise Brooks,Yaron S.N. Butterfield,Rebecca Carlsen,Scott L. Carter,Lynda Chin,Andy Chu,Eric Chuah,Kristian Cibulskis,Amanda Clarke,Simon G. Coetzee,Noreen Dhalla,Timothy R. Fennell,Sheila A. Fisher,Stacey Gabriel,Gad Getz,Richard A. Gibbs,Ranabir Guin,Angela Hadjipanayis,D. Neil Hayes,Toshinori Hinoue,Katherine A. Hoadley,Robert A. Holt,Alan P. Hoyle,Stuart R. Jefferys,Steven J.M. Jones,Corbin D. Jones,Raju Kucherlapati,Phillip H. Lai,Eric S. Lander,Semin Lee,Lee Lichtenstein,Yussanne Ma,Dennis T. Maglinte,Harshad S. Mahadeshwar,Marco A. Marra,Michael Mayo,Shaowu Meng,Matthew Meyerson,Piotr A. Mieczkowski,Richard A. Moore,Lisle E. Mose,Andrew J. Mungall,Angeliki Pantazi,Michael Parfenov,Peter J. Park,Joel S. Parker,Charles M. Perou,Alexei Protopopov,Xiaojia Ren,Jeffrey Roach,Thais S. Sabedot,Jacqueline E. Schein,Steven E. Schumacher,Jonathan G. Seidman,Sahil Seth,Hui Shen,Janae V. Simons,Payal Sipahimalani,Matthew G. Soloway,Xingzhi Song,Huandong Sun,Barbara Tabak,Angela Tam,Donghui Tan,Jiabin Tang,Nina Thiessen,Timothy J. Triche,David Van Den Berg,Umadevi Veluvolu,Scot Waring,Daniel J. Weisenberger,Matthew D. Wilkerson,Tina Wong,Junyuan Wu,Liu Xi,Andrew Wei Xu,Lixing Yang,Travis I. Zack,Jianhua Zhang,B. Arman Aksoy,Harindra Arachchi,Chris Benz,Brady Bernard,Daniel E. Carlin,Juok Cho,Daniel DiCara,Scott Frazer,Gregory N. Fuller,Jianjiong Gao,Nils Gehlenborg,David Haussler,David I. Heiman,Lisa Iype,Anders Jacobsen,Zhenlin Ju,Sol Katzman,Hoon Kim,Theo A. Knijnenburg,Richard Kreisberg,Michael S. Lawrence,William M. Lee,Kalle Leinonen,Pei Lin,Shiyun Ling,Wen-Bin Liu,Yingchun Liu,Yuexin Liu,Yiling Lu,Gordon B. Mills,Sam Ng,Michael S. Noble,Evan O. Paull,Arvind Rao,Sheila Reynolds,Gordon Saksena,Zack Sanborn,Chris Sander,Nikolaus Schultz,Yasin Senbabaoglu,Ronglai Shen,Ilya Shmulevich,Rileen Sinha,Josh Stuart,S. Onur Sumer,Yichao Sun,Natalie Tasman,Barry S. Taylor,Doug Voet,Nils Weinhold,John N. Weinstein,Da Yang,Kosuke Yoshihara,Siyuan Zheng,Wei Zhang,Lihua Zou,Ty Abel,Sara Sadeghi,Mark L. Cohen,Jenny Eschbacher,Eyas M. Hattab,Aditya Raghunathan,Matthew Schniederjan,Dina Aziz,Gene Barnett,Wendi Barrett,Darell D. Bigner,Lori Boice,Cathy Brewer,Chiara Calatozzolo,Benito Campos,Carlos Gilberto Carlotti,Timothy A. Chan,Lucia Cuppini,Erin Curley,Stefania Cuzzubbo,Karen Devine,Francesco DiMeco,Rebecca Duell,J. Bradley Elder,Ashley Fehrenbach,Gaetano Finocchiaro,William A. Friedman,Jordonna Fulop,Johanna Gardner,Beth Hermes,Christel Herold-Mende,Christine Jungk,Ady Kendler,Norman L. Lehman,Eric S. Lipp,Ouida Liu,Randy Mandt,Mary McGraw,Roger E. McLendon,Christopher M. McPherson,Luciano Neder,Phuong L. Nguyen,Ardene Noss,Raffaele Nunziata,Quinn T. Ostrom,Cheryl A. Palmer,Alessandro Perin,Bianca Pollo,Alexander Potapov,Olga Potapova,W. Kimryn Rathmell,D L Rotin,Lisa Scarpace,Cathy Schilero,Kelly Senecal,Kristen Shimmel,Vsevolod Shurkhay,Suzanne Sifri,Rosy Singh,Andrew E. Sloan,Kathy Smolenski,Susan M. Staugaitis,Ruth Steele,Leigh B. Thorne,Daniela Pretti da Cunha Tirapelli,Andreas Unterberg,Mahitha Vallurupalli,Yun Wang,Ronald E. Warnick,Felicia Williams,Yingli Wolinsky,Sue E. Bell,Mara Rosenberg,Chip Stewart,Franklin W. Huang,Jonna Grimsby,Amie Radenbaugh,Jianan Zhang +306 more
TL;DR: The integration of genomewide data from multiple platforms delineated three molecular classes of lower-grade gliomas that were more concordant with IDH, 1p/19q, and TP53 status than with histologic class.
Journal ArticleDOI
Genomic Classification of Cutaneous Melanoma
Rehan Akbani,Kadir C. Akdemir,B. Arman Aksoy,Monique Albert,Adrian Ally,Samirkumar B. Amin,Harindra Arachchi,Arshi Arora,J. Todd Auman,Brenda Ayala,Julien Baboud,Miruna Balasundaram,Saianand Balu,Nandita Barnabas,John M. S. Bartlett,Pam Bartlett,Boris C. Bastian,Stephen B. Baylin,Madhusmita Behera,Dmitry Belyaev,Christopher C. Benz,Brady Bernard,Rameen Beroukhim,Natalie Bir,Aaron D. Black,Tom Bodenheimer,Lori Boice,Genevieve M. Boland,Riccardo Bono,Moiz S. Bootwalla,Marcus Bosenberg,Jay Bowen,Reanne Bowlby,Christopher A. Bristow,Laura Brockway-Lunardi,Denise Brooks,Jakub Brzezinski,Wiam Bshara,Elizabeth Buda,William R. Burns,Yaron S.N. Butterfield,Michael Button,Tiffany L. Calderone,Giancarlo Antonini Cappellini,Candace D. Carter,Scott L. Carter,Lynn Cherney,Andrew D. Cherniack,Aaron Chevalier,Lynda Chin,Juok Cho,Raymond J. Cho,Yoon La Choi,Andy Chu,Sudha Chudamani,Kristian Cibulskis,Giovanni Ciriello,Amanda Clarke,Stephen Coons,Leslie Cope,Daniel Crain,Erin Curley,Ludmila Danilova,Stefania D'Atri,Tanja Davidsen,Michael A. Davies,Keith A. Delman,John A. Demchok,Qixia A. Deng,Yonathan Lissanu Deribe,Noreen Dhalla,Rajiv Dhir,Daniel DiCara,Michael Dinikin,Michael Dubina,J. Stephen Ebrom,Sophie Egea,Greg Eley,Jay Engel,Jennifer Eschbacher,Konstantin V. Fedosenko,Ina Felau,Timothy R. Fennell,Martin L. Ferguson,Sheila Fisher,Keith T. Flaherty,Scott Frazer,Jessica Frick,Victoria Fulidou,Stacey Gabriel,Jianjiong Gao,Johanna Gardner,Levi A. Garraway,Julie M. Gastier-Foster,Carmelo Gaudioso,Nils Gehlenborg,Giannicola Genovese,Mark Gerken,Jeffrey E. Gershenwald,Gad Getz,Carmen Gomez-Fernandez,Thomas Gribbin,Jonna Grimsby,Benjamin Gross,Ranabir Guin,Tony Gutschner,Angela Hadjipanayis,Ruth Halaban,Benjamin Hanf,David Haussler,Lauren E. Haydu,D. Neil Hayes,Nicholas K. Hayward,David I. Heiman,Lynn M. Herbert,James G. Herman,Peter Hersey,Katherine A. Hoadley,Eran Hodis,Robert A. Holt,Dave S.B. Hoon,Susan Hoppough,Alan P. Hoyle,Franklin W. Huang,Mei Huang,Sharon K. Huang,Carolyn M. Hutter,Matthew Ibbs,Lisa Iype,Anders Jacobsen,Valerie Jakrot,Alyssa Janning,William R. Jeck,Stuart R. Jefferys,Mark A. Jensen,Corbin D. Jones,Steven J.M. Jones,Zhenlin Ju,Hojabr Kakavand,Hyojin Kang,Richard F. Kefford,Fadlo R. Khuri,Jaegil Kim,John M. Kirkwood,Joachim Klode,Anil Korkut,Konstanty Korski,Michael Krauthammer,Raju Kucherlapati,Lawrence N. Kwong,Witold Kycler,Marc Ladanyi,Phillip H. Lai,Peter W. Laird,Eric S. Lander,Michael S. Lawrence,Alexander J. Lazar,Radoslaw Łaźniak,Darlene Lee,Jeffrey E. Lee,Junehawk Lee,Kenneth K. Lee,Semin Lee,William Lee,Ewa Leporowska,Kristen M. Leraas,Haiyan I. Li,Tara M. Lichtenberg,Lee Lichtenstein,Pei Lin,Shiyun Ling,Jia Liu,Ouida Liu,Wen-Bin Liu,Georgina V. Long,Yiling Lu,Singer Ma,Yussanne Ma,Andrzej Mackiewicz,Harshad S. Mahadeshwar,Jared Malke,David Mallery,Georgy Manikhas,Graham J. Mann,Marco A. Marra,Brenna Matejka,Michael Mayo,Sousan Mehrabi,Shaowu Meng,Matthew Meyerson,Piotr A. Mieczkowski,John P. Miller,Martin L. Miller,Gordon B. Mills,Fedor Moiseenko,Richard A. Moore,Scott Morris,Carl Morrison,Donald L. Morton,Stergios J. Moschos,Lisle E. Mose,Florian L. Muller,Andrew J. Mungall,D. Murawa,Pawel Murawa,Bradley A. Murray,Luigi Nezi,Sam Ng,Dana Nicholson,Michael S. Noble,Adeboye Osunkoya,Taofeek K. Owonikoko,Bradley A. Ozenberger,Elena Pagani,Oxana Paklina,Angeliki Pantazi,Michael Parfenov,Jeremy Parfitt,Peter J. Park,Woong-Yang Park,Joel S. Parker,Francesca Passarelli,Robert Penny,Charles M. Perou,Todd Pihl,Olga Potapova,Victor G. Prieto,Alexei Protopopov,Michael J. Quinn,Amie Radenbaugh,Kunal Rai,Suresh Ramalingam,Ayush T. Raman,Nilsa C. Ramirez,Ricardo Ramirez,Uma Rao,W. Kimryn Rathmell,Xiaojia Ren,Sheila Reynolds,Jeffrey Roach,A. Gordon Robertson,Merrick I. Ross,Jason Roszik,Giandomenico Russo,Gordon Saksena,Charles Saller,Yardena Samuels,Chris Sander,Cindy Sander,George E. Sandusky,Netty Santoso,Melissa Saul,Robyn P. M. Saw,Dirk Schadendorf,Jacqueline E. Schein,Nikolaus Schultz,Steven E. Schumacher,Charles Schwallier,Richard A. Scolyer,Jonathan G. Seidman,Pedamallu Chandra Sekhar,Harmanjatinder S. Sekhon,Yasin Senbabaoglu,Sahil Seth,Kerwin F. Shannon,Samantha Sharpe,Norman E. Sharpless,Kenna R. Mills Shaw,Candace Shelton,Troy Shelton,Ronglai Shen,Margi Sheth,Yan Shi,Carolyn J. Shiau,Ilya Shmulevich,Gabriel Sica,Janae V. Simons,Rileen Sinha,Payal Sipahimalani,Heidi J. Sofia,Matthew G. Soloway,Xingzhi Song,Carrie Sougnez,Andrew J. Spillane,Arkadiusz Spychała,Jonathan R. Stretch,Joshua M. Stuart,Wiktoria Maria Suchorska,Antje Sucker,S. Onur Sumer,Yichao Sun,Maria Synott,Barbara Tabak,Teresa R. Tabler,Angela Tam,Donghui Tan,Jiabin Tang,Roy Tarnuzzer,Katherine Tarvin,Honorata Tatka,Barry S. Taylor,M. Teresiak,Nina Thiessen,John F. Thompson,Leigh B. Thorne,Vesteinn Thorsson,Jeffrey M. Trent,Timothy J. Triche,Kenneth Y. Tsai,Peiling Tsou,David Van Den Berg,Eliezer M. Van Allen,Umadevi Veluvolu,Roeland Verhaak,Douglas Voet,Olga Voronina,Vonn Walter,Jessica Walton,Yunhu Wan,Yuling Wang,Zhining Wang,Scot Waring,Ian R. Watson,Nils Weinhold,John N. Weinstein,Daniel J. Weisenberger,Peter White,Matthew D. Wilkerson,James S. Wilmott,Lisa Wise,Maciej Wiznerowicz,Scott E. Woodman,Chang Jiun Wu,Chia Chin Wu,Junyuan Wu,Ye Wu,Ruibin Xi,Andrew Wei Xu,Da Yang,Liming Yang,Lixing Yang,Travis I. Zack,Jean C. Zenklusen,Hailei Zhang,Jianhua Zhang,Wei Zhang,Xiaobei Zhao,Jingchun Zhu,Kelsey Zhu,Lisa Zimmer,Erik Zmuda,Lihua Zou +351 more
TL;DR: This clinicopathological and multi-dimensional analysis suggests that the prognosis of melanoma patients with regional metastases is influenced by tumor stroma immunobiology, offering insights to further personalize therapeutic decision-making.
Journal ArticleDOI
Comprehensive molecular characterization of urothelial bladder carcinoma
John N. Weinstein,Rehan Akbani,Bradley M. Broom,Wenyi Wang,Roeland Verhaak,David J. McConkey,Seth P. Lerner,Margaret Morgan,Chad J. Creighton,Carolyn L. Smith,Andrew D. Cherniack,Jaegil Kim,Chandra Sekhar Pedamallu,Michael S. Noble,Hikmat Al-Ahmadie,Victor E. Reuter,Jonathan E. Rosenberg,Dean F. Bajorin,Bernard H. Bochner,David B. Solit,Theresa M. Koppie,Brian D. Robinson,Dmitry A. Gordenin,David C. Fargo,Leszek J. Klimczak,Steven A. Roberts,Jessie Au,Peter W. Laird,Toshinori Hinoue,Nikolaus Schultz,Ricardo Ramirez,Donna E. Hansel,Katherine A. Hoadley,William Y. Kim,Jeffrey S. Damrauer,Stephen B. Baylin,Andrew J. Mungall,A. Gordon Robertson,Andy Chu,David J. Kwiatkowski,Carrie Sougnez,Kristian Cibulskis,Lee Lichtenstein,Andrey Sivachenko,Chip Stewart,Michael S. Lawrence,Gad Getz,Eric S. Lander,Stacey B. Gabrie,Lawrence A. Donehower,Scott L. Carter,Gordon Saksena,Steven E. Schumacher,Samuel S. Freeman,Joonil Jung,Ami S. Bhatt,Trevor J. Pugh,Rameen Beroukhim,Matthew Meyerson,Adrian Ally,Miruna Balasundaram,Yaron S.N. Butterfield,Noreen Dhalla,Carrie Hirst,Robert A. Holt,Steven J.M. Jones,Darlene Lee,Haiyan I. Li,Marco A. Marra,Michael Mayo,Richard A. Moore,Jacqueline E. Schein,Payal Sipahimalani,Angela Tam,Nina Thiessen,Tina Wong,Natasja Wye,Reanne Bowlby,Eric Chuah,Ranabir Guin,Hui Shen,Moiz S. Bootwalla,Timothy J. Triche,Phillip H. Lai,David Van Den Berg,Daniel J. Weisenberger,Saianand Balu,Tom Bodenheimer,Alan P. Hoyle,Stuart R. Jefferys,Shaowu Meng,Lisle E. Mose,Janae V. Simons,Mathew G. Soloway,Junyuan Wu,Joel S. Parker,D. Neil Hayes,Jeffrey Roach,Elizabeth Buda,Corbin D. Jones,Piotr A. Mieczkowski,Donghui Tan,Umadevi Veluvolu,Scot Waring,J. Todd Auman,Charles M. Perou,Matthew D. Wilkerson,Netty Santoso,Michael Parfenov,Xiaojia Ren,Angeliki Pantazi,Angela Hadjipanayis,Jonathan G. Seidman,Raju Kucherlapati,Semin Lee,Lixing Yang,Peter J. Park,Andrew Wei Xu,Alexei Protopopov,Jianhua Zhang,Christopher A. Bristow,Harshad S. Mahadeshwar,Sahil Seth,Xingzhi Song,Jiabin Tang,Dong Zeng,Lynda Chin,Lynda Chin,Charles C. Guo,Tod D. Casasent,Wenbin Liu,Zhenlin Ju,Thomas C. Motter,Bo Peng,Michael Ryan,Xiaoping Su,Ji Yeon Yang,Philip L. Lorenzi,Hui Yao,Nianxiang Zhang,Jiexin Zhang,Gordon B. Mills,Juok Cho,Daniel DiCara,Scott Frazer,Nils Gehlenborg,David I. Heiman,Pei Lin,Yingchun Liu,Petar Stojanov,Doug Voet,Hailei Zhang,Lihua Zou,Brady Bernard,Dick Kreisberg,Sheila Reynolds,Hector Rovira,Ilya Shmulevich,Jianjiong Gao,Anders Jacobsen,B. Arman Aksoy,Yevgeniy Antipin,Giovanni Ciriello,Gideon Dresdner,Benjamin Gross,William Lee,Boris Reva,Ronglai Shen,Rileen Sinha,S. Onur Sumer,Nils Weinhold,Marc Ladanyi,Chris Sander,Christopher C. Benz,Daniel E. Carlin,David Haussler,Sam Ng,Evano Paull,Joshua M. Stuart,Jing Zhu,Yuexin Liu,Wei Zhang,Barry S. Taylor,Tara M. Lichtenberg,Erik Zmuda,Thomas Barr,Aaron D. Black,Myra M. George,Benjamin Hanf,Carmen Helsel,Cynthia McAllister,Nilsa C. Ramirez,Nilsa C. Ramirez,Teresa R. Tabler,Stephanie Weaver,Lisa Wise,Jay Bowen,Julie M. Gastier-Foster,Julie M. Gastier-Foster,Weiguo Jian,Sebrina A Tello,Michael Ittman,Patricia Castro,Whitney D. McClenden,Richard A. Gibbs,Charles Saller,Katherine Tarvin,Jennifer DiPiero,Jennifer Owens,Roni J. Bollag,Qiang Li,Paul M. Weinberger,Christine Czerwinski,Lori Huelsenbeck-Dill,Mary Iacocca,Nicholas J. Petrelli,Brenda Rabeno,Pat Swanson,Troy Shelton,Erin Curley,Johanna Gardner,David Mallery,Robert Penny,Nguyen Van Bang,Phan Thi Hanh,Bernard Kohl,Xuan Van Le,Bui Duc Phu,Richard Thorp,Nguyen Viet Tien,Le Quang Vinh,George E. Sandusky,Eric J. Burks,Kimberly R. Christ,Jason R. Gee,Antonia H. Holway,Alireza Moinzadeh,Andrea Sorcini,Travis Sullivan,Ilana Rebecca Garcia-Grossman,Ashley Marie Regazzi,Lori Boice,W.K. Rathmell,Leigh B. Thorne,Sheldon I. Bastacky,Benjamin Davies,Rajiv Dhir,Jeffrey R. Gingrich,Ronald L. Hrebinko,Jodi K. Maranchie,Joel B. Nelson,Anil V. Parwani,Wiam Bshara,Carmelo Gaudioso,Carl Morrison,Vina Alexopoulou,John M. S. Bartlett,Jay Engel,Sugy Kodeeswaran,Tatjana Antic,Peter H. O'Donnell,Norm D. Smith,Gary D. Steinberg,Sophie C. Egea,Carmen Gomez-Fernandez,Lynn M. Herbert,Merce Jorda,Mark S. Soloway,Allison Beaver,Suzie Carter,Payal Kapur,Cheryl M. Lewis,Yair Lotan,Jolanta Bondaruk,Bogdan Czerniak,Eila C. Skinner,Kenneth Aldape,Mark A. Jensen,Ari B. Kahn,Todd Pihl,David Pot,Deepak Srinivasan,Yunhu Wan,Martin L. Ferguson,Jean C. Zenklusen,Tanja Davidsen,John A. Demchok,Kenna R. Mills Shaw,Kenna R. Mills Shaw,Margi Sheth,Roy Tarnuzzer,Zhining Wang,Liming Yang,Carolyn M. Hutter,Bradley A. Ozenberger,Heidi J. Sofia,Greg Eley +296 more
TL;DR: Ch Chromatin regulatory genes were more frequently mutated in urothelial carcinoma than in any other common cancer studied so far, indicating the future possibility of targeted therapy for chromatin abnormalities.