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Michael F. Lin

Researcher at Massachusetts Institute of Technology

Publications -  44
Citations -  25299

Michael F. Lin is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 32, co-authored 44 publications receiving 23142 citations. Previous affiliations of Michael F. Lin include Broad Institute & Vassar College.

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Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

Sushmita Roy, +95 more
- 24 Dec 2010 - 
TL;DR: The Drosophila Encyclopedia of DNA Elements (modENCODE) project as mentioned in this paper has been used to map transcripts, histone modifications, chromosomal proteins, transcription factors, replication proteins and intermediates, and nucleosome properties across a developmental time course and in multiple cell lines.
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A high-resolution map of human evolutionary constraint using 29 mammals.

Kerstin Lindblad-Toh, +69 more
- 27 Oct 2011 - 
TL;DR: The comparison of related genomes has emerged as a powerful lens for genome interpretation and sequencing and comparative analysis of 29 eutherian genomes confirm that at least 5.5% of the human genome has undergone purifying selection, and locate constrained elements covering ∼4.2%" of the genome.
Journal ArticleDOI

Evolution of pathogenicity and sexual reproduction in eight Candida genomes.

TL;DR: There are significant expansions of cell wall, secreted and transporter gene families in pathogenic species, suggesting adaptations associated with virulence in Candida albicans species.