N
Nina K. Serwas
Researcher at University of California, San Francisco
Publications - 25
Citations - 1144
Nina K. Serwas is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Immunodeficiency & Hematopoietic stem cell transplantation. The author has an hindex of 16, co-authored 24 publications receiving 743 citations. Previous affiliations of Nina K. Serwas include Austrian Academy of Sciences & University of California, Berkeley.
Papers
More filters
Journal ArticleDOI
Global absence and targeting of protective immune states in severe COVID-19.
Alexis J. Combes,Tristan Courau,Nicholas F. Kuhn,Kenneth H. Hu,Arja Ray,William S. Chen,Nayvin W. Chew,Simon J. Cleary,Divyashree Kushnoor,Gabriella C Reeder,Alan Shen,Jessica Tsui,Kamir J Hiam-Galvez,Priscila Muñoz-Sandoval,Wandi S Zhu,David Lee,Yang Sun,Ran You,Mélia Magnen,Lauren Rodriguez,Kwok W. Im,Nina K. Serwas,Aleksandra Leligdowicz,Colin R. Zamecnik,Rita P. Loudermilk,Michael R. Wilson,Chun Jimmie Ye,Gabriela K. Fragiadakis,Mark R. Looney,Vincent Chan,Alyssa Ward,Sidney A. Carrillo,Michael A. Matthay,David J. Erle,Prescott G. Woodruff,Charles Langelier,Kirsten N. Kangelaris,Carolyn M. Hendrickson,Carolyn S. Calfee,Arjun A. Rao,Matthew F. Krummel +40 more
TL;DR: In this article, the authors performed a whole-blood-preserving single-cell analysis protocol to integrate contributions from all major immune cell types of the blood, including neutrophils, monocytes, platelets, lymphocytes and the contents of the serum.
Journal ArticleDOI
Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections
Kerry Dobbs,Cecilia Domínguez Conde,Shen-Ying Zhang,Silvia Parolini,Magali Audry,Janet Chou,Emma Haapaniemi,Sevgi Keles,Ivan Bilic,Satoshi Okada,Michel J. Massaad,Samuli Rounioja,Adel M Alwahadneh,Nina K. Serwas,Kelly Capuder,Ergin Çiftçi,Kerstin Felgentreff,Toshiro K. Ohsumi,Vincent Pedergnana,Bertrand Boisson,Sule Haskologlu,Arzu Ensari,Michael Schuster,Alessandro Moretta,Yuval Itan,Ornella Patrizi,Flore Rozenberg,Pierre Lebon,Janna Saarela,Mikael Knip,Slavé Petrovski,David Goldstein,Roberta E. Parrott,Berna Savaş,Axel Schambach,Giovanna Tabellini,Christoph Bock,Talal A. Chatila,Anne Marie Comeau,Raif S. Geha,Laurent Abel,Rebecca H. Buckley,Aydan Ikinciogullari,Waleed Al-Herz,Merja Helminen,Figen Dogu,Jean-Laurent Casanova,Kaan Boztug,Luigi D. Notarangelo +48 more
TL;DR: Autosomal recessive DOCK2 deficiency is a new mendelian disorder with pleiotropic defects of hematopoietic and nonhematopoetic immunity and children with clinical features of combined immunodeficiencies, especially with early-onset, invasive infections, may have this condition.
Journal ArticleDOI
An expanded universe of cancer targets.
William C. Hahn,Joel S. Bader,Theodore P. Braun,Andrea Califano,Paul A. Clemons,Brian J. Druker,Andrew J. Ewald,Haian Fu,Subhashini Jagu,Christopher J. Kemp,William Kim,Calvin J. Kuo,Michael T. McManus,Gordon B. Mills,Xiulei Mo,Nidhi Sahni,Stuart L. Schreiber,Jessica A. Talamas,Pablo Tamayo,Jeffrey W. Tyner,Bridget K. Wagner,William A. Weiss,Daniela S. Gerhard,Vlado Dančík,Shubhroz Gill,Bruce K. Hua,Tanaz Sharifnia,Vasanthi S. Viswanathan,Yilong Zou,Filemon S. Dela Cruz,Andrew L. Kung,Brent R. Stockwell,Jesse S. Boehm,Josh Dempster,Robert T. Manguso,Francisca Vazquez,Lee Cooper,Yuhong Du,Andrey A. Ivanov,Sagar Lonial,Carlos S. Moreno,Qiankun Niu,Taofeek K. Owonikoko,Suresh S. Ramalingam,Matthew A. Reyna,Wei Zhou,Carla Grandori,Ilya Shmulevich,Elizabeth M. Swisher,Jitong Cai,Issac S. Chan,Matthew Dunworth,Yuchen Ge,Dan Georgess,Eloise M. Grasset,Elodie Henriet,Hildur Knutsdottir,Michael G. Lerner,Veena Padmanaban,Matthew C. Perrone,Yasir Suhail,Yohannes Tsehay,Manisha Warrier,Quin Morrow,Tamilla Nechiporuk,Nicola Long,Jennifer Saultz,Andy Kaempf,Jessica Minnier,Cristina E. Tognon,Stephen E. Kurtz,Anupriya Agarwal,Jordana Brown,Kevin Watanabe-Smith,Tania Q. Vu,Thomas Jacob,Yunqi Yan,Bridget Robinson,Evan F. Lind,Yoko Kosaka,Emek Demir,Joseph Estabrook,Michael Grzadkowski,Olga Nikolova,Ken Chen,Ben Deneen,Han Liang,Michael C. Bassik,Asmita Bhattacharya,Kevin C. Brennan,Christina Curtis,Olivier Gevaert,Hanlee P. Ji,Kasper Karlsson,Kremena Karagyozova,Yuan-Hung Lo,Katherine N. Liu,Michitaka Nakano,Anuja Sathe,Amber R. Smith,Kaitlyn Spees,Wing Hing Wong,Kanako Yuki,Matt Hangauer,Dan S. Kaufman,Allan Balmain,Saumya R. Bollam,Wei-Ching Chen,Qi-Wen Fan,Kelly Kersten,Matthew F. Krummel,Yun Rose Li,Marie Menard,Nicole Nasholm,Christin Schmidt,Nina K. Serwas,Hiroyuki Yoda,Alan Ashworth,Sourav Bandyopadhyay,Trevor Bivona,Gabriel Eades,Stefan Oberlin,Neil Tay,Yuhao Wang,Jonathan S. Weissman +124 more
TL;DR: A framework is described for this expanded list of cancer targets, providing novel opportunities for clinical translation and indicating that the diversity of therapeutic targets engendered by non-oncogene dependencies is much larger than the list of recurrently mutated genes.
Journal ArticleDOI
CD55 Deficiency, Early-Onset Protein-Losing Enteropathy, and Thrombosis
Ahmet Ozen,William A. Comrie,Rico Chandra Ardy,Cecilia Domínguez Conde,Buket Dalgic,Ömer Faruk Beşer,Aaron Morawski,Elif Karakoc-Aydiner,Engin Tutar,Safa Baris,Figen Özçay,Nina K. Serwas,Yu Zhang,Helen F. Matthews,Stefania Pittaluga,Les R. Folio,Aysel Ünlüsoy Aksu,Joshua McElwee,Ana Krolo,Ayca Kiykim,Zeren Baris,Meltem Gulsan,Ismail Ogulur,Scott B. Snapper,Roderick H. J. Houwen,Helen L. Leavis,Deniz Ertem,Renate Kain,Sinan Sari,Tülay Erkan,Helen C. Su,Kaan Boztug,Michael J. Lenardo +32 more
TL;DR: CD55 deficiency with hyperactivation of complement, angiopathic thrombosis, and protein‐losing enteropathy (the CHAPLE syndrome) is caused by abnormal complement activation due to biallelic loss‐of‐function mutations in CD55.
Journal ArticleDOI
Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells
Megan K. Ruhland,Edward W. Roberts,En Cai,Adriana M. Mujal,Kyle Marchuk,Casey Beppler,David Nam,Nina K. Serwas,Mikhail Binnewies,Matthew F. Krummel +9 more
TL;DR: It is demonstrated that tumor proteins are carried to the LN within discrete vesicles inside DCs and are then transferred among DC subsets, and a synapse is formed between interactingDCs and vesicle transfer takes place in the absence of free exosomes.