Bharathiar University

About: Bharathiar University is a education organization based out in Coimbatore, Tamil Nadu, India. It is known for research contribution in the topics: Thin film & Adsorption. The organization has 5812 authors who have published 8628 publications receiving 143934 citations. The organization is also known as: BU.

An overview of targeted cancer therapy.

Abstract: Cancer is a multifactorial disease and is one of the leading causes of death worldwide. The contributing factors include specific genetic background, chronic exposure to various environmental stresses and improper diet. All these risk factors lead to the accumulation of molecular changes or mutations in some important proteins in cells which contributes to the initiation of carcinogenesis. Chemotherapy is an effective treatment against cancer but undesirable chemotherapy reactions and the development of resistance to drugs which results in multi-drug resistance (MDR) are the major obstacles in cancer chemotherapy. Strategies which are in practice with limited success include alternative formulations e.g., liposomes, resistance modulation e.g., PSC833, antidotes/toxicity modifiers e.g., ICRF-187 and gene therapy. Targeted therapy is gaining importance due to its specificity towards cancer cells while sparing toxicity to off-target cells. The scope of this review involves the various strategies involved in targeted therapy like-monoclonal antibodies, prodrug, small molecule inhibitors and nano-particulate antibody conjugates.

Redox additive/active electrolytes: a novel approach to enhance the performance of supercapacitors

Abstract: Currently, supercapacitors (SCs) are a promising field in the area of energy storage devices. In the last few decades, different types of carbon based materials with suitable surface modifications, metal oxides, metal hydroxides, conducting polymers and their various composites have been used as electrodes to improve the energy performance of SCs. In addition, different technologies like asymmetric and hybrid systems have also been introduced. Interestingly, another alternative approach has been proposed recently by a few research groups, wherein electrolytes (liquid and polymer) can enhance the performance of the SCs via redox reactions at the electrode–electrolyte interface, by introducing redox additives or mediators in the electrolytes. The main advantage of this new technique is its simple and safe preparation method, along with cost effectiveness compared to the preparation of some active electrode materials. Hence it is believed that identification of suitable redox additives or species in electrolytes will be a hotspot in the field of SCs in the coming years.