Institution
Institute of Chartered Accountants of Nigeria
About: Institute of Chartered Accountants of Nigeria is a based out in . It is known for research contribution in the topics: Population & Adipose tissue. The organization has 528 authors who have published 579 publications receiving 18688 citations.
Topics: Population, Adipose tissue, Insulin resistance, Genome-wide association study, Extracorporeal membrane oxygenation
Papers published on a yearly basis
Papers
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TL;DR: Patients carrying a mutation affecting the cytoplasmic tail of BMPRII were characterized by an older age at diagnosis compared with other BMPR2 mutation carriers, less severe hemodynamic characteristics, and a greater chance of being a long-term responder to calcium channel blockers.
31 citations
University of Zielona Góra1, Medical University of Łódź2, Memorial Hospital of South Bend3, Institute of Chartered Accountants of Nigeria4, University of Paris5, Cliniques Universitaires Saint-Luc6, Sahlgrenska University Hospital7, Ljubljana University Medical Centre8, Forest Research Institute9, University of Latvia10, Medical University of Graz11, Augsburg College12, Heidelberg University13, Harokopio University14, University of Debrecen15, University of Zagreb16, Charité17, Tallinn University of Technology18, Charles University in Prague19, University of Milan20
31 citations
TL;DR: Functional profiling from 16 S rRNA gene data showed marked differences between T2DM and non-T2DM controls, providing an insight into gut microbiome composition in Emirati population and its potential role in the development of diabetes mellitus.
Abstract: Type 2 diabetes mellitus (T2DM) drastically affects the population of Middle East countries with an ever-increasing number of overweight and obese individuals. The precise links between T2DM and gut microbiome composition remain elusive in these populations. Here, we performed 16 S rRNA and ITS2- gene based microbial profiling of 50 stool samples from Emirati adults with or without T2DM. The four major enterotypes initially described in westernized cohorts were retrieved in this Emirati population. T2DM and non-T2DM healthy controls had different microbiome compositions, with an enrichment in Prevotella enterotype in non-T2DM controls whereas T2DM individuals had a higher proportion of the dysbiotic Bacteroides 2 enterotype. No significant differences in microbial diversity were observed in T2DM individuals after controlling for cofounding factors, contrasting with reports from westernized cohorts. Interestingly, fungal diversity was significantly decreased in Bacteroides 2 enterotype. Functional profiling from 16 S rRNA gene data showed marked differences between T2DM and non-T2DM controls, with an enrichment in amino acid degradation and LPS-related modules in T2DM individuals, whereas non-T2DM controls had increased abundance of carbohydrate degradation modules in concordance with enterotype composition. These differences provide an insight into gut microbiome composition in Emirati population and its potential role in the development of diabetes mellitus.
31 citations
TL;DR: The findings establish a pathogenic role for increased Phe levels in cardiac aging, linking plasma Phe Levels to cardiac senescence via dysregulated Phe catabolism along a hepatic-cardiac axis and highlight Phe/PAH modulation as a potential therapeutic strategy for age-associated cardiac impairment.
Abstract: Background: Aging myocardium undergoes progressive cardiac hypertrophy and interstitial fibrosis with diastolic and systolic dysfunction. Recent metabolomics studies shed light on amino acids in ag...
30 citations
TL;DR: Genetic and lesional hypothalamic obesities have different consequences for phenotypic features such as body composition or BMR compared with primary obese patients.
Abstract: Comparison of body composition, basal metabolic rate and metabolic outcomes of adults with Prader Willi syndrome or lesional hypothalamic disease, with primary obesity
30 citations
Authors
Showing all 528 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Ronald M. Evans | 199 | 708 | 166722 |
| Thierry Poynard | 119 | 668 | 64548 |
| Heikki Joensuu | 108 | 571 | 50300 |
| Gilles Montalescot | 100 | 641 | 58644 |
| François Cambien | 92 | 251 | 36260 |
| Antoine Danchin | 80 | 483 | 30219 |
| Laurence Tiret | 79 | 194 | 25231 |
| Karine Clément | 78 | 275 | 32185 |
| Karine Clément | 73 | 228 | 14710 |
| Pascal Ferré | 69 | 241 | 23969 |
| Michael T. Osterholm | 68 | 260 | 22624 |
| Vincent Jarlier | 67 | 278 | 17060 |
| Florent Soubrier | 67 | 226 | 24486 |
| Stephen H. Caldwell | 66 | 308 | 18527 |
| Christian Funck-Brentano | 64 | 267 | 70432 |