Institution
Lund University
Education•Lund, Sweden•
About: Lund University is a education organization based out in Lund, Sweden. It is known for research contribution in the topics: Population & Cancer. The organization has 42345 authors who have published 124676 publications receiving 5016438 citations. The organization is also known as: Lunds Universitet & University of Lund.
Topics: Population, Cancer, Insulin, Breast cancer, Diabetes mellitus
Papers published on a yearly basis
Papers
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TL;DR: An integrated method for clustering of QRS complexes is presented which includes basis function representation and self-organizing neural networks (NN's) and outperforms both a published supervised learning method as well as a conventional template cross-correlation clustering method.
Abstract: An integrated method for clustering of QRS complexes is presented which includes basis function representation and self-organizing neural networks (NN's). Each QRS complex is decomposed into Hermite basis functions and the resulting coefficients and width parameter are used to represent the complex. By means of this representation, unsupervised self-organizing NNs are employed to cluster the data into 25 groups. Using the MIT-BIH arrhythmia database, the resulting clusters are found to exhibit a very low degree of misclassification (1.5%). The integrated method outperforms, on the MIT-BIH database, both a published supervised learning method as well as a conventional template cross-correlation clustering method.
555 citations
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TL;DR: Evidence is accumulating that the functional size of organs and aspects of the metabolic physiology of an individual may show great flexibility over timescales of weeks and even days depending on physiological status, environmental conditions and behavioural goals.
Abstract: Organ structures and correlated metabolic features (e.g. metabolic rate) have often taken as fixed attributes of fully grown individual vertebrates. When measurements of these attributes became available they were often used as representative values for the species, disregarding the specific conditions during which the mesurement were made. Evidence is accumulating that the functional size of organs and aspects of the metabolic physiology of an individual may show great flexibility over timescales of weeks and even days depending on physiological status, environmental conditions and behavioural goals. This flexibility is a way for animals to cope successfully with a much wider range of conditions occurring during various life-cycle events than fixed metabolic machinery would allow. Such phenotypic flexibility is likely to be a common adaptive syndrome, typical of vertebrates living in variable environments.
555 citations
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J. L. Abelleira Fernandez1, J. L. Abelleira Fernandez2, C. Adolphsen3, A. Akay4 +195 more•Institutions (54)
TL;DR: The Large Hadron Electron Collider (LHeC) as discussed by the authors was designed to achieve an integrated luminosity of O(100 ),fb$^{-1}, which is the cleanest high resolution microscope of mankind.
Abstract: This document provides a brief overview of the recently published report on the design of the Large Hadron Electron Collider (LHeC), which comprises its physics programme, accelerator physics, technology and main detector concepts. The LHeC exploits and develops challenging, though principally existing, accelerator and detector technologies. This summary is complemented by brief illustrations of some of the highlights of the physics programme, which relies on a vastly extended kinematic range, luminosity and unprecedented precision in deep inelastic scattering. Illustrations are provided regarding high precision QCD, new physics (Higgs, SUSY) and electron-ion physics. The LHeC is designed to run synchronously with the LHC in the twenties and to achieve an integrated luminosity of O(100)\,fb$^{-1}$. It will become the cleanest high resolution microscope of mankind and will substantially extend as well as complement the investigation of the physics of the TeV energy scale, which has been enabled by the LHC.
553 citations
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TL;DR: The sin ϑ theorem for Hermitian linear operators in Davis and Kahan as discussed by the authors is applicable to computational solution of overdetermined systems of linear equations and especially cover the rank deficient case when the matrix is replaced by one of lower rank.
Abstract: LetA be anm ×n-matrix which is slightly perturbed. In this paper we will derive an estimate of how much the invariant subspaces ofA
H
A andAA
H
will then be affected. These bounds have the sin ϑ theorem for Hermitian linear operators in Davis and Kahan [1] as a special case. They are applicable to computational solution of overdetermined systems of linear equations and especially cover the rank deficient case when the matrix is replaced by one of lower rank.
553 citations
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TL;DR: The lipid raft-associated protein caveolin-1 (CAV1), in analogy with its previously described role in virus uptake, negatively regulates the uptake of exosomes and induces the phosphorylation of several downstream targets known to associate with lipid rafts as signaling and sorting platforms, such as extracellular signal-regulated kinase-1/2 and heat shock protein 27 (HSP27).
553 citations
Authors
Showing all 42777 results
Name | H-index | Papers | Citations |
---|---|---|---|
Yi Chen | 217 | 4342 | 293080 |
Fred H. Gage | 216 | 967 | 185732 |
Kari Stefansson | 206 | 794 | 174819 |
Mark I. McCarthy | 200 | 1028 | 187898 |
Ruedi Aebersold | 182 | 879 | 141881 |
Jie Zhang | 178 | 4857 | 221720 |
Feng Zhang | 172 | 1278 | 181865 |
Martin G. Larson | 171 | 620 | 117708 |
Michael Snyder | 169 | 840 | 130225 |
Unnur Thorsteinsdottir | 167 | 444 | 121009 |
Anders Björklund | 165 | 769 | 84268 |
Carl W. Cotman | 165 | 809 | 105323 |
Dennis R. Burton | 164 | 683 | 90959 |
Jaakko Kaprio | 163 | 1532 | 126320 |
Panos Deloukas | 162 | 410 | 154018 |