Institution
Lund University
Education•Lund, Sweden•
About: Lund University is a education organization based out in Lund, Sweden. It is known for research contribution in the topics: Population & Cancer. The organization has 42345 authors who have published 124676 publications receiving 5016438 citations. The organization is also known as: Lunds Universitet & University of Lund.
Topics: Population, Cancer, Insulin, Breast cancer, Diabetes mellitus
Papers published on a yearly basis
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TL;DR: Pythia version 6 represents a merger of the Pythia 5, Jetset 7 and SPythia programs, with many improvements as discussed by the authors, which can be used to generate high-energy physics events.
1,723 citations
TL;DR: It is concluded that antihypertensive treatment in hypertensive men and women aged 70-84 confers highly significant and clinically relevant reductions in cardiovascular morbidity and mortality as well as in total mortality.
1,721 citations
TL;DR: In this article, the Savitzky-Golay filter was used to smooth out noise in NDVI time-series, specifically that caused primarily by cloud contamination and atmospheric variability.
1,717 citations
Cristen J. Willer, Elizabeth K. Speliotes1, Elizabeth K. Speliotes2, Ruth J. F. Loos +163 more•Institutions (36)
TL;DR: Several of the likely causal genes are highly expressed or known to act in the central nervous system (CNS), emphasizing, as in rare monogenic forms of obesity, the role of the CNS in predisposition to obesity.
Abstract: Common variants at only two loci, FTO and MC4R, have been reproducibly associated with body mass index (BMI) in humans. To identify additional loci, we conducted meta-analysis of 15 genome-wide association studies for BMI (n > 32,000) and followed up top signals in 14 additional cohorts (n > 59,000). We strongly confirm FTO and MC4R and identify six additional loci (P < 5 x 10(-8)): TMEM18, KCTD15, GNPDA2, SH2B1, MTCH2 and NEGR1 (where a 45-kb deletion polymorphism is a candidate causal variant). Several of the likely causal genes are highly expressed or known to act in the central nervous system (CNS), emphasizing, as in rare monogenic forms of obesity, the role of the CNS in predisposition to obesity.
1,710 citations
Lawrence Berkeley National Laboratory1, Buck Institute for Research on Aging2, Lund University3, University of California, San Francisco4, National Institutes of Health5, University College London6, Harvard University7, Columbia University Medical Center8, Emory University9, Humanitas University10, Queen Mary University of London11, University of Milan12, Stanford University13, Albert Einstein College of Medicine14, Veterans Health Administration15, University of California, Los Angeles16, European University of Madrid17
TL;DR: The multi-level mechanisms underlying SCI and several risk factors that promote this health-damaging phenotype, including infections, physical inactivity, poor diet, environmental and industrial toxicants and psychological stress are described.
Abstract: Although intermittent increases in inflammation are critical for survival during physical injury and infection, recent research has revealed that certain social, environmental and lifestyle factors can promote systemic chronic inflammation (SCI) that can, in turn, lead to several diseases that collectively represent the leading causes of disability and mortality worldwide, such as cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease and autoimmune and neurodegenerative disorders. In the present Perspective we describe the multi-level mechanisms underlying SCI and several risk factors that promote this health-damaging phenotype, including infections, physical inactivity, poor diet, environmental and industrial toxicants and psychological stress. Furthermore, we suggest potential strategies for advancing the early diagnosis, prevention and treatment of SCI.
1,708 citations
Authors
Showing all 42777 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Yi Chen | 217 | 4342 | 293080 |
| Fred H. Gage | 216 | 967 | 185732 |
| Kari Stefansson | 206 | 794 | 174819 |
| Mark I. McCarthy | 200 | 1028 | 187898 |
| Ruedi Aebersold | 182 | 879 | 141881 |
| Jie Zhang | 178 | 4857 | 221720 |
| Feng Zhang | 172 | 1278 | 181865 |
| Martin G. Larson | 171 | 620 | 117708 |
| Michael Snyder | 169 | 840 | 130225 |
| Unnur Thorsteinsdottir | 167 | 444 | 121009 |
| Anders Björklund | 165 | 769 | 84268 |
| Carl W. Cotman | 165 | 809 | 105323 |
| Dennis R. Burton | 164 | 683 | 90959 |
| Jaakko Kaprio | 163 | 1532 | 126320 |
| Panos Deloukas | 162 | 410 | 154018 |