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Institution

Maastricht University

EducationMaastricht, Limburg, Netherlands
About: Maastricht University is a education organization based out in Maastricht, Limburg, Netherlands. It is known for research contribution in the topics: Population & Health care. The organization has 19263 authors who have published 53291 publications receiving 2266866 citations. The organization is also known as: Universiteit Maastricht & UM.


Papers
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Journal ArticleDOI
TL;DR: Caregivers should be aware of the extent of these behavioural changes of bilateral STN DBS and a risk/benefit evaluation should be performed for individual patients.

396 citations

Journal ArticleDOI
Rosalind A. Eeles1, Zsofia Kote-Jarai, Ali Amin Al Olama2, Graham G. Giles3, Graham G. Giles4, Michelle Guy, Gianluca Severi4, Gianluca Severi3, Kenneth Muir5, John L. Hopper4, Brian E. Henderson6, Christopher A. Haiman6, Johanna Schleutker7, Freddie C. Hamdy8, David E. Neal2, Jenny L Donovan9, Janet L. Stanford10, Janet L. Stanford11, Elaine A. Ostrander12, Sue A. Ingles6, Esther M. John13, Stephen N. Thibodeau14, Daniel J. Schaid14, Jong Y. Park15, Amanda B. Spurdle16, Judith A. Clements17, Joanne L. Dickinson18, Christiane Maier, Walther Vogel, Thilo Dörk19, Timothy R. Rebbeck20, Kathleen A. Cooney21, Lisa A. Cannon-Albright22, Pierre O. Chappuis23, Pierre Hutter, Maurice P. Zeegers24, Radka Kaneva25, Hong Wei Zhang26, Yong-Jie Lu27, William D. Foulkes28, Dallas R. English4, Daniel Leongamornlert, Malgorzata Tymrakiewicz, Jonathan J. Morrison2, Audrey Ardern-Jones1, Amanda L. Hall1, Lynne T. O'Brien, Rosemary A. Wilkinson, Edward J. Saunders, Elizabeth Page1, Emma J. Sawyer, Stephen M. Edwards, David P. Dearnaley1, Alan Horwich1, Robert Huddart1, Vincent Khoo1, Chris Parker1, Nicholas Van As1, C. R. J. Woodhouse1, Alan Thompson1, Tim Christmas1, Chris Ogden1, Colin Cooper, Melissa C. Southey4, Artitaya Lophatananon5, Jo Fen Liu5, Laurence N. Kolonel29, Loic Le Marchand29, Tiina Wahlfors7, Teuvo L.J. Tammela, Anssi Auvinen7, Sarah J Lewis9, Angela Cox30, Liesel M. FitzGerald18, Liesel M. FitzGerald10, Joseph S. Koopmeiners11, Joseph S. Koopmeiners10, Danielle M. Karyadi12, Erika M. Kwon12, Mariana C. Stern6, Roman Corral6, Amit Joshi6, Ahva Shahabi6, Shannon K. McDonnell14, Thomas A. Sellers15, Julio M. Pow-Sang15, Suzanne K. Chambers, Joanne F. Aitken31, Robert A. Gardiner31, Jyotsna Batra17, Mary-Anne Kedda17, Felicity Lose16, Felicity Lose17, Andrea M. Polanowski18, Briony Patterson18, Jürgen Serth19, Andreas Meyer19, Manuel Luedeke, Klara Stefflova20, Anna M. Ray21, Ethan M. Lange32, J. M. Farnham22, Humera Khan33, C. Slavov, Atanaska Mitkova25, Guangwen Cao26, Douglas F. Easton2 
TL;DR: The study is extended to evaluate promising associations in a second stage in which 43,671 SNPs are genotyped in 3,650 PrCa cases and 3,940 controls and in a third stage involving an additional 16,229 cases and 14,821 controls from 21 studies.
Abstract: Prostate cancer (PrCa) is the most frequently diagnosed cancer in males in developed countries To identify common PrCa susceptibility alleles, we previously conducted a genome-wide association study in which 541,129 SNPs were genotyped in 1,854 PrCa cases with clinically detected disease and in 1,894 controls We have now extended the study to evaluate promising associations in a second stage in which we genotyped 43,671 SNPs in 3,650 PrCa cases and 3,940 controls and in a third stage involving an additional 16,229 cases and 14,821 controls from 21 studies In addition to replicating previous associations, we identified seven new prostate cancer susceptibility loci on chromosomes 2, 4, 8, 11 and 22 (with P = 16 x 10(-8) to P = 27 x 10(-33))

396 citations

Journal ArticleDOI
TL;DR: A smoking prevention project in six European countries (European Smoking prevention Framework Approach) was developed, featuring activities for adolescents, schools and parents, including out-of-school activities, which revealed that the project's ambitions were high, but were limited by various constraints including time and delays in receiving funds.
Abstract: A smoking prevention project in six European countries (European Smoking prevention Framework Approach) was developed, featuring activities for adolescents, schools and parents, including out-of-school activities. Consensus meetings resulted in agreement between the countries on goals, objectives and theoretical methods. Countries' specific objectives were also included. National diversities required country-specific methods to realize the goals and objectives. The community intervention trial was used as the research design. Since interventions took place at the community level, communities or regions were allocated at random to the experimental or control conditions. Complete randomization was achieved in four countries. At baseline, smoking prevalence among 23 125 adolescents at the start of the project was 5.6% for regular smoking and 4.0% for daily smoking. Smoking prevalence rates were higher among girls than boys in all countries as far as weekly smoking was concerned. Process evaluations revealed that the project's ambitions were high, but were limited by various constraints including time and delays in receiving funds. Future smoking prevention projects should aim to identify the effective components within the social influence approach as well as within broader approaches and on reaching sustained effects.

396 citations

Journal ArticleDOI
TL;DR: The International Definitions Committee of 13 experts from seven countries repeatedly communicated, proposed new definitions and presented at the 2nd International Consultation on Sexual Medicine in Paris July 2003 as discussed by the authors, aiming to revise definitions based on an alternative model reflecting women's reasons/incentives for sexual activity beyond any initial awareness of sexual desire.

396 citations

Journal ArticleDOI
TL;DR: For redifferentiation of dedifferentiated HACs, 3D cultures exhibit the most potent chondrogenic potential, whereas a hypertrophic phenotype is best achieved in 2D cultures.

395 citations


Authors

Showing all 19492 results

NameH-indexPapersCitations
Edward Giovannucci2061671179875
Julie E. Buring186950132967
Aaron R. Folsom1811118134044
John J.V. McMurray1781389184502
Alvaro Pascual-Leone16596998251
Lex M. Bouter158767103034
David T. Felson153861133514
Walter Paulus14980986252
Michael Conlon O'Donovan142736118857
Randy L. Buckner141346110354
Philip Scheltens1401175107312
Anne Tjønneland139134591556
Ewout W. Steyerberg139122684896
James G. Herman138410120628
Andrew Steptoe137100373431
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023107
2022344
20214,523
20203,881
20193,367
20183,019