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Institution

Massachusetts Institute of Technology

EducationCambridge, Massachusetts, United States
About: Massachusetts Institute of Technology is a education organization based out in Cambridge, Massachusetts, United States. It is known for research contribution in the topics: Population & Laser. The organization has 116795 authors who have published 268000 publications receiving 18272025 citations. The organization is also known as: MIT & M.I.T..


Papers
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Journal ArticleDOI
24 Mar 2006-Cell
TL;DR: A screen based on high-content imaging was developed to identify genes required for mitotic progression in human cancer cells and applied to an arrayed set of 5,000 unique shRNA-expressing lentiviruses that target 1,028 human genes, providing a widely applicable resource for loss-of-function screens.

1,760 citations

Journal ArticleDOI
TL;DR: An algorithm for the c-approximate nearest neighbor problem in a d-dimensional Euclidean space, achieving query time of O(dn 1c2/+o(1)) and space O(DN + n1+1c2 + o(1) + 1/c2), which almost matches the lower bound for hashing-based algorithm recently obtained.
Abstract: In this article, we give an overview of efficient algorithms for the approximate and exact nearest neighbor problem. The goal is to preprocess a dataset of objects (e.g., images) so that later, given a new query object, one can quickly return the dataset object that is most similar to the query. The problem is of significant interest in a wide variety of areas.

1,759 citations

Journal ArticleDOI
TL;DR: It is found that over 600 positive associations between common gene variants and disease have been reported; these associations, if correct, would have tremendous importance for the prevention, prediction, and treatment of most common diseases.

1,758 citations

Journal ArticleDOI
31 Oct 1996-Nature
TL;DR: In this article, it was shown that light emission from single fluorescing nanocrystals of cadmium selenide under continuous excitation turns on and off intermittently with a characteristic timescale of about 0.5 seconds.
Abstract: SEMICONDUCTOR nanocrystals offer the opportunity to study the evolution of bulk materials properties as the size of a system increases from the molecular scale1,2. In addition, their strongly size-dependent optical properties render them attractive candidates as tunable light absorbers and emitters in optoelectronic devices such as light-emitting diodes3,4 and quantum-dot lasers5,6, and as optical probes of biological systems7. Here we show that light emission from single fluorescing nanocrystals of cadmium selenide under continuous excitation turns on and off intermittently with a characteristic timescale of about 0.5 seconds. This intermittency is not apparent from ensemble measurements on many nanocrystals. The dependence on excitation intensity and the change in on/off times when a passivating, high-bandgap shell of zinc sulphide encapsulates the nanocrystal8,9 suggests that the abrupt turning off of luminescence is caused by photo-ionization of the nanocrystal. Thus spectroscopic measurements on single nanocrystals can reveal hitherto unknown aspects of their photophysics.

1,757 citations

Posted Content
TL;DR: This work identifies obfuscated gradients, a kind of gradient masking, as a phenomenon that leads to a false sense of security in defenses against adversarial examples, and develops attack techniques to overcome this effect.
Abstract: We identify obfuscated gradients, a kind of gradient masking, as a phenomenon that leads to a false sense of security in defenses against adversarial examples. While defenses that cause obfuscated gradients appear to defeat iterative optimization-based attacks, we find defenses relying on this effect can be circumvented. We describe characteristic behaviors of defenses exhibiting the effect, and for each of the three types of obfuscated gradients we discover, we develop attack techniques to overcome it. In a case study, examining non-certified white-box-secure defenses at ICLR 2018, we find obfuscated gradients are a common occurrence, with 7 of 9 defenses relying on obfuscated gradients. Our new attacks successfully circumvent 6 completely, and 1 partially, in the original threat model each paper considers.

1,757 citations


Authors

Showing all 117442 results

NameH-indexPapersCitations
Eric S. Lander301826525976
Robert Langer2812324326306
George M. Whitesides2401739269833
Trevor W. Robbins2311137164437
George Davey Smith2242540248373
Yi Cui2201015199725
Robert J. Lefkowitz214860147995
David J. Hunter2131836207050
Daniel Levy212933194778
Rudolf Jaenisch206606178436
Mark J. Daly204763304452
David Miller2032573204840
David Baltimore203876162955
Rakesh K. Jain2001467177727
Ronald M. Evans199708166722
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023240
20221,124
202110,595
202011,922
201911,207
201810,883