Institution
Sun Yat-sen University
Education•Guangzhou, Guangdong, China•
About: Sun Yat-sen University is a education organization based out in Guangzhou, Guangdong, China. It is known for research contribution in the topics: Population & Cancer. The organization has 115149 authors who have published 113763 publications receiving 2286465 citations. The organization is also known as: Zhongshan University & SYSU.
Topics: Population, Cancer, Medicine, Cell growth, Metastasis
Papers published on a yearly basis
Papers
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TL;DR: This paper first introduces blockchains and smart contracts, then presents the challenges in smart contracts as well as recent technical advances, and gives a categorization of smart contract applications.
506 citations
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TL;DR: In this study, obese patients had increased odds of progressing to severe COVID-19 and clinicians should pay close attention to obese patients, who should be carefully managed with prompt and aggressive treatment.
Abstract: OBJECTIVE Patients with obesity are at increased risk of exacerbations from viral respiratory infections. However, the association of obesity with the severity of coronavirus disease 2019 (COVID-19) is unclear. We examined this association using data from the only referral hospital in Shenzhen, China. RESEARCH DESIGN AND METHODS A total of 383 consecutively hospitalized patients with COVID-19 admitted from 11 January 2020 to 16 February 2020 and followed until 26 March 2020 at the Third People’s Hospital of Shenzhen were included. Underweight was defined as a BMI RESULTS Of the 383 patients, 53.1% were normal weight, 4.2% were underweight, 32.0% were overweight, and 10.7% were obese at admission. Obese patients tended to have symptoms of cough (P = 0.03) and fever (P = 0.06) compared with patients who were not obese. Compared with normal weight patients, those who were overweight had 1.84-fold odds of developing severe COVID-19 (odds ratio [OR] 1.84, 95% CI 0.99–3.43, P = 0.05), while those who were obese were at 3.40-fold odds of developing severe disease (OR 3.40, 95% CI 1.40–2.86, P = 0.007), after adjusting for age, sex, epidemiological characteristics, days from disease onset to hospitalization, presence of hypertension, diabetes, cardiovascular disease, chronic obstructive pulmonary disease, liver disease and cancer, and drug used for treatment. Additionally, after similar adjustment, men who were obese versus those who were normal weight were at increased odds of developing severe COVID-19 (OR 5.66, 95% CI 1.80–17.75, P = 0.003). CONCLUSIONS In this study, obese patients had increased odds of progressing to severe COVID-19. As the severe acute respiratory syndrome coronavirus 2 may continue to spread worldwide, clinicians should pay close attention to obese patients, who should be carefully managed with prompt and aggressive treatment.
506 citations
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TL;DR: In this article, a review of the development of carbon-based materials and their composites with alloy materials as well as their prospects and challenges for sodium ion battery anodes is presented.
504 citations
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TL;DR: The crystal structure of the N-terminal RNA binding domain of SARS-CoV-2 nucleocapsid protein is determined and several atomic resolution features are provided, guiding the design of novel antiviral agents specific targeting to Sars-Cov-2.
503 citations
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TL;DR: It is hoped that this updated review paper will attract more attention to ginger and its further applications, including its potential to be developed into functional foods or nutraceuticals for the prevention and management of chronic diseases.
Abstract: Ginger (Zingiber officinale Roscoe) is a common and widely used spice. It is rich in various chemical constituents, including phenolic compounds, terpenes, polysaccharides, lipids, organic acids, and raw fibers. The health benefits of ginger are mainly attributed to its phenolic compounds, such as gingerols and shogaols. Accumulated investigations have demonstrated that ginger possesses multiple biological activities, including antioxidant, anti-inflammatory, antimicrobial, anticancer, neuroprotective, cardiovascular protective, respiratory protective, antiobesity, antidiabetic, antinausea, and antiemetic activities. In this review, we summarize current knowledge about the bioactive compounds and bioactivities of ginger, and the mechanisms of action are also discussed. We hope that this updated review paper will attract more attention to ginger and its further applications, including its potential to be developed into functional foods or nutraceuticals for the prevention and management of chronic diseases.
501 citations
Authors
Showing all 115971 results
Name | H-index | Papers | Citations |
---|---|---|---|
Yi Chen | 217 | 4342 | 293080 |
Jing Wang | 184 | 4046 | 202769 |
Yang Gao | 168 | 2047 | 146301 |
Yang Yang | 164 | 2704 | 144071 |
Peter Carmeliet | 164 | 844 | 122918 |
Frank J. Gonzalez | 160 | 1144 | 96971 |
Xiang Zhang | 154 | 1733 | 117576 |
Rui Zhang | 151 | 2625 | 107917 |
Seeram Ramakrishna | 147 | 1552 | 99284 |
Joseph J.Y. Sung | 142 | 1240 | 92035 |
Joseph Lau | 140 | 1048 | 99305 |
Bin Liu | 138 | 2181 | 87085 |
Georgios B. Giannakis | 137 | 1321 | 73517 |
Kwok-Yung Yuen | 137 | 1173 | 100119 |
Shu Li | 136 | 1001 | 78390 |