Universidade Federal de Mato Grosso

About: Universidade Federal de Mato Grosso is a education organization based out in Cuiabá, Brazil. It is known for research contribution in the topics: Population & Species richness. The organization has 7748 authors who have published 10181 publications receiving 89994 citations.

Declining prevalence of hepatitis A virus antibodies among children from low socioeconomic groups reinforces the need for the implementation of hepatitis A vaccination in Brazil

Abstract: Age-related seroprevalence studies that have been conducted in Brazil have indicated a transition from a high to a medium endemicity of hepatitis A virus (HAV) infection in the population. However, most of these studies have focused on urban populations that experience lower incidence rates of HAV infection. In the current study, the prevalence of anti-HAV antibodies was investigated in children with a low socioeconomic status (SES) that live on the periphery of three capital cities in Brazil. A total of 1,162 dried blood spot samples were collected from individuals whose ages ranged from one-18 years and tested for anti-HAV antibodies. A large number of children under five years old (74.1-90%) were identified to be susceptible to HAV infection. The anti-HAV antibody prevalence reached ≥ 50% among those that were 10-14 years of age or older. The anti-HAV prevalence rates observed were characteristics of regions with intermediate level of hepatitis A endemicity. These data indicated that a large proportion of children with a low SES that live at the periphery of urban cities might be at risk of contracting an HAV infection. The hepatitis A vaccine that is currently offered in Brazil is only available for high-risk groups or at private clinics and is unaffordable for individuals with a lower SES. The results from this study suggest that the hepatitis A vaccine should be included in the Brazilian National Program for Immunisation.

Effects of xenobiotics on total antioxidant capacity.

Abstract: The objective of this article was to review the effects of xenobiotics on total antioxidant capacity (TAC). Measurement of TAC is appropriate for evaluation of the total antioxidant defenses of blood, cells, and different kinds of tissues and organs. TAC is reduced by alcoholism, smoking, and exposure to radiation, herbicides, carbon monoxide, carbon tetrachloride, lead, arsenic, mercury, cadmium, aluminum, and other toxic elements. The test is also an important tool in evaluating environmental and occupational exposure.

Vigilância de eventos adversos pós-vacinação e segurança de programas de imunização

Abstract: El objetivo de la revision fue analizar aspectos conceptuales y operacionales de sistemas de vigilancia de eventos adversos post vacuna. Fueron incluidos articulos disponibles en formato electronico, publicados entre 1985 y 2009, seleccionados en las bases PubMed/Medline, con las palabras clave: "vigilancia de eventos adversos post vacuna", "vigilancia post comercializacion", "seguridad de vacunas" y "estudios de Fase IV", y excluidos aquellos con foco en tipos especificos de tales eventos. Se senalaron los principales aspectos que justifican la importancia de los eventos adversos post vacuna en salud publica, los instrumentos que garantizan la seguridad de las vacunas y las finalidades, atributos, tipos, interpretaciones de datos, limitaciones y nuevos desafios de la vigilancia de eventos adversos post vacuna, asi como estrategias para aumentar su sensibilidad. Se concluye con desafios para los proximos anos, buscando seguridad y confiabilidad de los programas de vacunacion.