Institution
University of Palermo
Education•Palermo, Italy•
About: University of Palermo is a education organization based out in Palermo, Italy. It is known for research contribution in the topics: Population & Medicine. The organization has 15621 authors who have published 40250 publications receiving 964384 citations. The organization is also known as: Università degli Studi di Palermo & Universita degli Studi di Palermo.
Topics: Population, Medicine, Cancer, Context (language use), Catalysis
Papers published on a yearly basis
Papers
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15 May 2006TL;DR: This paper develops a rigorous, unified framework based on Ordinary Differential Equations (ODEs) to study epidemic routing and its variations, and investigates how resources such as buffer space and power can be traded for faster delivery.
Abstract: In this paper, we develop a rigorous, unified framework based on Ordinary Differential Equations (ODEs) to study epidemic routing and its variations. These ODEs can be derived as limits of Markovian models under a natural scaling as the number of nodes increases. While an analytical study of Markovian models is quite complex and numerical solution impractical for large networks, the corresponding ODE models yield closed-form expressions for several performance metrics of interest, and a numerical solution complexity that does not increase with the number of nodes. Using this ODE approach, we investigate how resources such as buffer space and power can be traded for faster delivery, illustrating the differences among the various epidemic schemes considered. Finally we consider the effect of buffer management by complementing the forwarding models with Markovian and fluid buffer models.
328 citations
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TL;DR: Low concentrations of epigallocatechin-3-gallate, the major green tea catechin, induces HO-1 by ARE/Nrf2 pathway in hippocampal neurons, and by this induction, it is able to protect neurons against different models of oxidative damages and identify a novel class of compounds that could be used for therapeutic purposes as preventive agents against cognitive decline.
Abstract: In recent years, there has been a growing interest, supported by a large number of experimental and epidemiological studies, for the beneficial effects of some phenolic substances, contained in commonly used spices and herbs, in preventing various age-related pathologic conditions, ranging from cancer to neurodegenerative diseases. Although the exact mechanisms by which polyphenols promote these effects remain to be elucidated, several reports have shown their ability to stimulate a general xenobiotic response in the target cells, activating multiple defense genes. Data from our and other laboratories have previously demonstrated that curcumin, the yellow pigment of curry, strongly induces heme-oxygenase-1 (HO-1) expression and activity in different brain cells via the activation of heterodimers of NF-E2-related factors 2 (Nrf2)/antioxidant responsive element (ARE) pathway. Many studies clearly demonstrate that activation ofNrf2 target genes, and particularly HO-1, in astrocytes and neurons is strongly protective against inflammation, oxidative damage, and cell death. In the central nervous system, the HO system has been reported to be very active, and its modulation seems to play a crucial role in the pathogenesis of neurodegenerative disorders. Recent and unpublished data from our group revealed that low concentrations of epigallocatechin-3-gallate, the major green tea catechin, induces HO-1 by ARE/Nrf2 pathway in hippocampal neurons, and by this induction, it is able to protect neurons against different models of oxidative damages. Furthermore, we have demonstrated that other phenolics, such as caffeic acid phenethyl ester and ethyl ferulate, are also able to protect neurons via HO-1 induction. These studies identify a novel class of compounds that could be used for therapeutic purposes as preventive agents against cognitive decline.
327 citations
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TL;DR: The current understanding of colorectal CSCs is reviewed, including their origin, relationship to stem cells of the intestine, phenotypic characterization, and underlying regulatory mechanisms.
327 citations
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TL;DR: In this paper, thermal and hydrothermal treatments have been applied to an amorphous TiO2 precursor for obtaining nanosized TiO 2 particles (P11t and P11h, respectively) of different photocatalytic properties.
327 citations
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TL;DR: Straw mulch is very effective in reducing soil erodibility and surface runoff, and this benefit was achieved immediately after the application of the straw.
326 citations
Authors
Showing all 15895 results
Name | H-index | Papers | Citations |
---|---|---|---|
Robin M. Murray | 171 | 1539 | 116362 |
Frede Blaabjerg | 147 | 2161 | 112017 |
Jean Bousquet | 145 | 1288 | 96769 |
Zhanhu Guo | 128 | 886 | 53378 |
Jean Ballet | 115 | 263 | 46301 |
Antonio Facchetti | 111 | 602 | 51885 |
Michele Pagano | 97 | 306 | 42211 |
Frank Z. Stanczyk | 93 | 620 | 30244 |
Eleonora Troja | 91 | 271 | 30873 |
Francesco Sciortino | 90 | 536 | 28956 |
Zev Rosenwaks | 89 | 772 | 32039 |
Antonio Russo | 88 | 934 | 34563 |
Carlo Salvarani | 88 | 730 | 31699 |
Giuseppe Basso | 87 | 643 | 33320 |
Antonio Craxì | 86 | 659 | 39463 |