Biochemistry of arsenic detoxification
TLDR
While the overall schemes for arsenic resistance are similar in prokaryotes and eukaryotes, some of the specific proteins are the products of separate evolutionary pathways.About:
This article is published in FEBS Letters.The article was published on 2002-10-02 and is currently open access. It has received 726 citations till now. The article focuses on the topics: Arsenate reductase activity & Arsenate reductase.read more
Citations
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Journal ArticleDOI
The Ecology of Arsenic
Ronald S. Oremland,John F. Stolz +1 more
TL;DR: This work reviews what is known about arsenic-metabolizing bacteria and their potential impact on speciation and mobilization of arsenic in nature and investigates their role in aquifers.
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Wound healing - A literature review.
Ana Cristina Gonzalez,Tila Fortuna Costa,Zilton A. Andrade,Alena Ribeiro Alves Peixoto Medrado +3 more
TL;DR: The purpose of this review is to describe the various cellular and molecular aspects involved in the skin healing process.
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Arsenic hazards: strategies for tolerance and remediation by plants
Rudra Deo Tripathi,Sudhakar Srivastava,Seema Mishra,Nandita Singh,Rakesh Tuli,Dharmendra K. Gupta,Frans J. M. Maathuis +6 more
TL;DR: Recent advances in arsenic tolerance are discussed and their potential applications, particularly in the context of multigenic engineering approaches, are discussed.
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Arsenic binding to proteins.
TL;DR: Although the adverse health effects arising from exposure to arsenic have been well-recognized, the mechanism(s) of action responsible for the diverse range of health effects are complicated and poorly understood.
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Occurrence of arsenic contamination in Canada: sources, behavior and distribution.
TL;DR: An analysis of the currently available information on recognized problem areas, and an overview of current knowledge of the principal hydrogeochemical processes of arsenic transportation and transformation are provided, however, a more detailed understanding of local sources of arsenic and mechanisms of arsenic release is required.
References
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Families of arsenic transporters.
TL;DR: Yeasts extrude arsenite using Acr3p, a plasma membrane carrier protein, or sequester it in vacuoles as the glutathione conjugate using Ycf1p, an ABC transporter.
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The glycerol channel Fps1p mediates the uptake of arsenite and antimonite in Saccharomyces cerevisiae
Robert W. Wysocki,Cyrille C. Chéry,Donata Wawrzycka,Marijn Van Hulle,Rita Cornelis,Johan M. Thevelein,Markus J. Tamás +6 more
TL;DR: It is shown by direct transport assays that arsenite uptake is mediated by Fps1p, and the first report describing a eukaryotic uptake mechanism for arsenite and antimonite and its involvement in metalloid tolerance is described.
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Nucleotide sequence of the structural genes for an anion pump. The plasmid-encoded arsenical resistance operon.
TL;DR: A model is proposed in which these gene products form an anion translocating ATPase for extrusion of arsenite and arsenate from resistant cells.
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The MRP2/cMOAT Transporter and Arsenic-Glutathione Complex Formation Are Required for Biliary Excretion of Arsenic
Subbarao V. Kala,Matthew W. Neely,Geeta Kala,Christopher I. Prater,Donna W. Atwood,Jeffrey S. Rice,Michael W. Lieberman +6 more
TL;DR: It is shown that transport of arsenic into bile depends on the MRP2/cMOAT transporter and that glutathione is obligatory for such transport, and may help explain the increased susceptibility of malnourished human populations to arsenic.
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Two systems for the uptake of phosphate in Escherichia coli.
TL;DR: A comparison of strains of Escherichia coli K-12 showed that one of the systems (PIT) was fully constitutive, required no binding protein, and operated in spheroplasts, while the other system, PST, was repressible by phosphate concentrations above 1 mM, required the phosphate-binding protein for full activity, and did not operate in sp Heroplasts.