Biochemistry of arsenic detoxification
TLDR
While the overall schemes for arsenic resistance are similar in prokaryotes and eukaryotes, some of the specific proteins are the products of separate evolutionary pathways.About:
This article is published in FEBS Letters.The article was published on 2002-10-02 and is currently open access. It has received 726 citations till now. The article focuses on the topics: Arsenate reductase activity & Arsenate reductase.read more
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Unraveling the role of plant growth-promoting rhizobacteria in the alleviation of arsenic phytotoxicity: A review.
Sayanta Mondal,Krishnendu Pramanik,Sudip Kumar Ghosh,Priyanka Pal,Tanushree Mondal,Tithi Soren,Tushar Kanti Maiti +6 more
TL;DR: The dual functionality of As-resistant PGPR i.e., phytostimulation and minimization of Asinduced phytotoxic damages are one of the main focal points of as discussed by the authors.
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Uptake and biotransformation of arsenate in the lichen Hypogymnia physodes (L.) Nyl.
TL;DR: The results suggest that at least two types of As(V) detoxification exist in lichens; arsenite excretion and methylation.
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Role of Rhizobacteria in Reduction of Arsenic Uptake by Plants: A Review
TL;DR: In this paper, the identification, characterization and bioremediation advances in effect and significance of As-resistant rhizobacteria in phytoremediations of heavy metal contaminated soils to prevent the transport arsenic metal from root to shoot, and prevent the uptake by plants.
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In vivo specificity of Ure2 protection from heavy metal ion and oxidative cellular damage in Saccharomyces cerevisiae.
Rajendra Rai,Terrance G. Cooper +1 more
TL;DR: Experiments suggest that Ure2 possesses a central role in metal ion detoxification, a role not demonstrably shared by either of the two known S. cerevisiae glutathione S‐transferases, Gtt1 and Gtt2, or the two glutaredoxins, Grx1 and Grx2, that also possess glutathionation S‐ transferase activity.
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Influence of inoculation with Glomus mosseae or Acaulospora morrowiae on arsenic uptake and translocation by maize
TL;DR: Deposition of As in external mycelium indicates a possible role of mycorrhizal fungi in the detoxification of As by maize plants and may have influenced root As efflux.
References
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Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.
TL;DR: Related sequences in both alpha and beta and in other enzymes that bind ATP or ADP in catalysis help to identify regions contributing to an adenine nucleotide binding fold in both ATP synthase subunits.
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CLUSTAL: A package for performing multiple sequence alignment on a microcomputer
Desmond G. Higgins,Paul M. Sharp +1 more
TL;DR: An approach for performing multiple alignments of large numbers of amino acid or nucleotide sequences is described, based on first deriving a phylogenetic tree from a matrix of all pairwise sequence similarity scores obtained using a fast pairwise alignment algorithm.
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Classification and evolution of P-loop GTPases and related ATPases.
TL;DR: In this article, the authors compared sequences and available structures for all the widely distributed representatives of the P-loop GTPases and GTPase-related proteins with the aim of constructing an evolutionary classification for this superclass of proteins and reconstructing the principal events in their evolution.
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Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells.
Miroslav Styblo,L.M. Del Razo,Libia Vega,Dori R. Germolec,Edward L. LeCluyse,G. Hamilton,W Reed,Changqing Wang,William R. Cullen,David J. Thomas +9 more
TL;DR: It is suggested that trivalent methylated arsenicals, intermediary products of arsenic methylation, may significantly contribute to the adverse effects associated with exposure to iAs, and high methylation capacity does not protect cells from the acute toxicity of triavalent arsenicals.
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The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.
Inka Leier,Gabriele Jedlitschky,Ulrike Buchholz,Susan P.C. Cole,Roger G. Deeley,Dietrich Keppler +5 more
TL;DR: It is concluded that the biosynthetic release of LTC4 from cells is mediated by the 190-kDa product of the MRP gene, a primary-active ATP-dependent export pump for conjugates of lipophilic compounds with glutathione and several other anionic residues.