Biochemistry of arsenic detoxification
TLDR
While the overall schemes for arsenic resistance are similar in prokaryotes and eukaryotes, some of the specific proteins are the products of separate evolutionary pathways.About:
This article is published in FEBS Letters.The article was published on 2002-10-02 and is currently open access. It has received 726 citations till now. The article focuses on the topics: Arsenate reductase activity & Arsenate reductase.read more
Citations
More filters
Journal ArticleDOI
Co-expression of Cyanobacterial Genes for Arsenic Methylation and Demethylation in Escherichia coli Offers Insights into Arsenic Resistance.
TL;DR: It is proposed that coexistence of arsM and arsI genes in Nostoc could be advantageous for several reasons, and at low concentrations of arsenic, the MAs(III) produced by NsArsM will possibly have antibiotic-like properties and give the organism a competitive advantage.
Journal ArticleDOI
Function of arsATorf7orf8 of bacillus sp. CDB3 in arsenic resistance
TL;DR: The resulting abolishment of arsenate resistance suggests that the involvement of orf8 in arsenic resistance is not via reductase activity, and that the encoded ArsA may couple with the arsenite transporter, forming an ArsAY complex that can enhance arsenite extrusion efficiency.
Journal Article
Isolation and characterization of arsenic resistant bacteria from agricultural soil, and their potential for arsenic bioremediation
M. S. Selvi,Sundaresan Sasikumar,Sivasamy Gomathi,Prabhakaran Rajkumar,Ponnusamy Sasikumar,S. G. Sadasivam +5 more
TL;DR: The results revealed that the isolates BC1 and BC2 encoded arsenite oxidizing gene aoxA and arsenate reducing gene arsC respectively will be useful for the development of efficient bioremediation strategies in the detoxification of arsenic from polluted environments.
Journal ArticleDOI
Arsenite Resistance, Accumulation, and Volatilization Properties of Trichoderma asperellum SM-12F1, Penicillium janthinellum SM-12F4, and Fusarium oxysporum CZ-8F1
Qiufen Feng,Shiming Su,Xi-bai Zeng,Yangzhu Zhang,Lian-fang Li,Ling-yu Bai,Ran Duan,Zhiling Lin +7 more
TL;DR: The results indicated that all three fungal strains exhibited significant As(III)-resistance, and it seems that thesefungal strains can be used in the future to tackle As-contaminated environments.
Journal ArticleDOI
Bioaccumulation of Dissolved Arsenic in the Oyster Crassostrea virginica: A Radiotracer Study
TL;DR: The results indicate that C. virginica bioaccumulates As proportionally to the ambient dissolved As concentration, and retains it with similar efficiency regardless of exposure concentrations.
References
More filters
Journal ArticleDOI
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.
TL;DR: Related sequences in both alpha and beta and in other enzymes that bind ATP or ADP in catalysis help to identify regions contributing to an adenine nucleotide binding fold in both ATP synthase subunits.
Journal ArticleDOI
CLUSTAL: A package for performing multiple sequence alignment on a microcomputer
Desmond G. Higgins,Paul M. Sharp +1 more
TL;DR: An approach for performing multiple alignments of large numbers of amino acid or nucleotide sequences is described, based on first deriving a phylogenetic tree from a matrix of all pairwise sequence similarity scores obtained using a fast pairwise alignment algorithm.
Journal ArticleDOI
Classification and evolution of P-loop GTPases and related ATPases.
TL;DR: In this article, the authors compared sequences and available structures for all the widely distributed representatives of the P-loop GTPases and GTPase-related proteins with the aim of constructing an evolutionary classification for this superclass of proteins and reconstructing the principal events in their evolution.
Journal ArticleDOI
Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells.
Miroslav Styblo,L.M. Del Razo,Libia Vega,Dori R. Germolec,Edward L. LeCluyse,G. Hamilton,W Reed,Changqing Wang,William R. Cullen,David J. Thomas +9 more
TL;DR: It is suggested that trivalent methylated arsenicals, intermediary products of arsenic methylation, may significantly contribute to the adverse effects associated with exposure to iAs, and high methylation capacity does not protect cells from the acute toxicity of triavalent arsenicals.
Journal ArticleDOI
The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.
Inka Leier,Gabriele Jedlitschky,Ulrike Buchholz,Susan P.C. Cole,Roger G. Deeley,Dietrich Keppler +5 more
TL;DR: It is concluded that the biosynthetic release of LTC4 from cells is mediated by the 190-kDa product of the MRP gene, a primary-active ATP-dependent export pump for conjugates of lipophilic compounds with glutathione and several other anionic residues.