Biochemistry of arsenic detoxification
TLDR
While the overall schemes for arsenic resistance are similar in prokaryotes and eukaryotes, some of the specific proteins are the products of separate evolutionary pathways.About:
This article is published in FEBS Letters.The article was published on 2002-10-02 and is currently open access. It has received 726 citations till now. The article focuses on the topics: Arsenate reductase activity & Arsenate reductase.read more
Citations
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Book ChapterDOI
Microbial Remediation of Arsenic Contaminated Soil
TL;DR: The use of engineered microbes as selective biosorbents is an attractive green cure technology for the low cost and efficient removal of arsenic from soil as discussed by the authors, however, most of the studies are concentrated in laboratory and this should be tested in the field before its further implications.
Journal ArticleDOI
The effect of heavy metals on thiocyanate biodegradation by an autotrophic microbial consortium enriched from mine tailings
TL;DR: The autotrophic microbial consortium was capable of tolerating high concentrations of As, potential having adapted to higher As levels derived from the tailings source, and highlights the importance of considering metal co-contamination in bioreactor design and operation at mine sites.
Journal ArticleDOI
Hydrous ferric oxides (HFO's) precipitated from contaminated waters at several abandoned Sb deposits – Interdisciplinary assessment
TL;DR: In this paper , a comprehensive analysis of ochre sediments precipitated from Fe-rich drainage waters contaminated by arsenic and antimony is presented, which provides evidence of diverse microbial communities that exist in drainage waters and are highly important in the process of mobilization or immobilization of potentially toxic elements.
Journal ArticleDOI
On the aqueous solvation of AsO(OH)3vs. As(OH)3. Born–Oppenheimer molecular dynamics density functional theory cluster studies
Alejandro Ramírez-Solís,J. I. Amaro-Estrada,C. I. León-Pimentel,Jorge Hernández-Cobos,S E Garrido-Hoyos,Humberto Saint-Martin +5 more
TL;DR: Theoretical EXAFS spectra were obtained that showed good agreement with experimental data for As(iii) and As(v) in liquid water, albeit with somewhat longer As-O distances due to the level of theory employed.
References
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Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.
TL;DR: Related sequences in both alpha and beta and in other enzymes that bind ATP or ADP in catalysis help to identify regions contributing to an adenine nucleotide binding fold in both ATP synthase subunits.
Journal ArticleDOI
CLUSTAL: A package for performing multiple sequence alignment on a microcomputer
Desmond G. Higgins,Paul M. Sharp +1 more
TL;DR: An approach for performing multiple alignments of large numbers of amino acid or nucleotide sequences is described, based on first deriving a phylogenetic tree from a matrix of all pairwise sequence similarity scores obtained using a fast pairwise alignment algorithm.
Journal ArticleDOI
Classification and evolution of P-loop GTPases and related ATPases.
TL;DR: In this article, the authors compared sequences and available structures for all the widely distributed representatives of the P-loop GTPases and GTPase-related proteins with the aim of constructing an evolutionary classification for this superclass of proteins and reconstructing the principal events in their evolution.
Journal ArticleDOI
Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells.
Miroslav Styblo,L.M. Del Razo,Libia Vega,Dori R. Germolec,Edward L. LeCluyse,G. Hamilton,W Reed,Changqing Wang,William R. Cullen,David J. Thomas +9 more
TL;DR: It is suggested that trivalent methylated arsenicals, intermediary products of arsenic methylation, may significantly contribute to the adverse effects associated with exposure to iAs, and high methylation capacity does not protect cells from the acute toxicity of triavalent arsenicals.
Journal ArticleDOI
The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.
Inka Leier,Gabriele Jedlitschky,Ulrike Buchholz,Susan P.C. Cole,Roger G. Deeley,Dietrich Keppler +5 more
TL;DR: It is concluded that the biosynthetic release of LTC4 from cells is mediated by the 190-kDa product of the MRP gene, a primary-active ATP-dependent export pump for conjugates of lipophilic compounds with glutathione and several other anionic residues.