Biochemistry of arsenic detoxification
TLDR
While the overall schemes for arsenic resistance are similar in prokaryotes and eukaryotes, some of the specific proteins are the products of separate evolutionary pathways.About:
This article is published in FEBS Letters.The article was published on 2002-10-02 and is currently open access. It has received 726 citations till now. The article focuses on the topics: Arsenate reductase activity & Arsenate reductase.read more
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Book ChapterDOI
Potential for the Use of Rhizobacteria in the Sustainable Management of Contaminated Soils
TL;DR: A review of the use of rhizobacteria for restoration of sites co-contaminated with organic pollutants and heavy metals is presented in this paper, where the effectiveness of the external manipulation of the rhizosoil to overcome physical and chemical constraints to root establishment and to enhance pollutant removal is also examined.
Journal ArticleDOI
Metabolic Reconstruction Elucidates the Lifestyle of the Last Diplomonadida Common Ancestor.
TL;DR: The reconstructed whole metabolic networks of four extant diplomonad species as well as their ancestors are reconstructed using a bioinformatics approach and show that the metabolism within the group is under constant change throughout evolutionary time, in response to the environments that the different lineages explore.
Journal ArticleDOI
Impact of Zero-Valent Iron on Freshwater Bacterioplankton Metabolism as Predicted from 16S rRNA Gene Sequence Libraries.
TL;DR: In this paper, the effect of microscale and nanoscale zero-valent iron particles (mZVI and nZVI) on the abundance of different metabolic pathways in freshwater bacterial communities was inferred from metabolism modelling based on 16S rRNA gene sequence data using paprica pipeline.
Journal ArticleDOI
Nickel and Arsenite Responsive Proteomic Alterations in Cyanobacterium Anabaena PCC7120
TL;DR: It is demonstrated that arsenite appears to be more toxic than nickel, and some proteins are commonly regulated in response to the different metal, including ribulose1,5-bisphosphate carboxylase, chaperones and antioxidative defence proteins, whereas others were specifically induced by each metal.
References
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Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.
TL;DR: Related sequences in both alpha and beta and in other enzymes that bind ATP or ADP in catalysis help to identify regions contributing to an adenine nucleotide binding fold in both ATP synthase subunits.
Journal ArticleDOI
CLUSTAL: A package for performing multiple sequence alignment on a microcomputer
Desmond G. Higgins,Paul M. Sharp +1 more
TL;DR: An approach for performing multiple alignments of large numbers of amino acid or nucleotide sequences is described, based on first deriving a phylogenetic tree from a matrix of all pairwise sequence similarity scores obtained using a fast pairwise alignment algorithm.
Journal ArticleDOI
Classification and evolution of P-loop GTPases and related ATPases.
TL;DR: In this article, the authors compared sequences and available structures for all the widely distributed representatives of the P-loop GTPases and GTPase-related proteins with the aim of constructing an evolutionary classification for this superclass of proteins and reconstructing the principal events in their evolution.
Journal ArticleDOI
Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells.
Miroslav Styblo,L.M. Del Razo,Libia Vega,Dori R. Germolec,Edward L. LeCluyse,G. Hamilton,W Reed,Changqing Wang,William R. Cullen,David J. Thomas +9 more
TL;DR: It is suggested that trivalent methylated arsenicals, intermediary products of arsenic methylation, may significantly contribute to the adverse effects associated with exposure to iAs, and high methylation capacity does not protect cells from the acute toxicity of triavalent arsenicals.
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The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.
Inka Leier,Gabriele Jedlitschky,Ulrike Buchholz,Susan P.C. Cole,Roger G. Deeley,Dietrich Keppler +5 more
TL;DR: It is concluded that the biosynthetic release of LTC4 from cells is mediated by the 190-kDa product of the MRP gene, a primary-active ATP-dependent export pump for conjugates of lipophilic compounds with glutathione and several other anionic residues.