Cannabis sativa: The Plant of the Thousand and One Molecules
TLDR
Prospects on the benefits linked to the use of the -omics technologies, such as metabolomics and transcriptomics to speed up the identification and the large-scale production of lead agents from bioengineered Cannabis cell culture, are presented.Abstract:
Cannabis sativa L. is an important herbaceous species originating from Central Asia, which has been used in folk medicine and as a source of textile fiber since the dawn of times. This fast-growing plant has recently seen a resurgence of interest because of its multi-purpose applications: it is indeed a treasure trove of phytochemicals and a rich source of both cellulosic and woody fibers. Equally highly interested in this plant are the pharmaceutical and construction sectors, since its metabolites show potent bioactivities on human health and its outer and inner stem tissues can be used to make bioplastics and concrete-like material, respectively. In this review, the rich spectrum of hemp phytochemicals is discussed by putting a special emphasis on molecules of industrial interest, including cannabinoids, terpenes and phenolic compounds, and their biosynthetic routes. Cannabinoids represent the most studied group of compounds, mainly due to their wide range of pharmaceutical effects in humans, including psychotropic activities. The therapeutic and commercial interests of some terpenes and phenolic compounds, and in particular stilbenoids and lignans, are also highlighted in view of the most recent literature data. Biotechnological avenues to enhance the production and bioactivity of hemp secondary metabolites are proposed by discussing the power of plant genetic engineering and tissue culture. In particular two systems are reviewed, i.e., cell suspension and hairy root cultures. Additionally, an entire section is devoted to hemp trichomes, in the light of their importance as phytochemical factories. Ultimately, prospects on the benefits linked to the use of the -omics technologies, such as metabolomics and transcriptomics to speed up the identification and the large-scale production of lead agents from bioengineered Cannabis cell culture, are presented.read more
Citations
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Cannabinoids and Terpenes as an Antibacterial and Antibiofouling Promotor for PES Water Filtration Membranes.
Ismara Nadir,Nosheen Fatima Rana,Nasir M. Ahmad,Tahreem Tanweer,Amna Batool,Zara Taimoor,Sundus Riaz,Syed Mohsin Ali +7 more
TL;DR: The results of this study established cannabinoids and terpenes as an inexpensive solution for PES membrane surface modification and confirmed an effective antibacterial performance against Gram-positive and Gram-negative bacteria.
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Impact of enzymatic hydrolysis on the nutrients, phytochemicals and sensory properties of oil hemp seed cake (Cannabis sativa L. FINOLA variety).
Nora Pap,Leena Hamberg,Juha-Matti Pihlava,Jarkko Hellström,Pirjo Mattila,Merja Eurola,Anne Pihlanto +6 more
TL;DR: Sediments from the enzymatic treatment were tastier, with better color and smell than liquids, and the defatting process by SC-CO2 resulted in a higher lightness and the enzyme processing did not have effect on the color attributes.
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Bast fibre formation: insights from Next-Generation Sequencing
Gea Guerriero,Marc Behr,Aurélie Backes,Claudia Faleri,Jean-Francois Hausman,Stanley Lutts,Giampiero Cai +6 more
TL;DR: This review will focus on the current knowledge concerning bast fibre initiation and development by using a transcriptomic angle, in the light of the great advances that Next-Generation Sequencing (NGS) has fostered in the last years.
Journal ArticleDOI
Systematics and Botanical Characteristics of Industrial Hemp Cannabis Sativa L
TL;DR: The systematic affiliation of Cannabis has been controversial for many years, but today it is known that they belong to the order Rosales, family Cannabaceae, genus Cannabis, species – C. cannabis.
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Impact of Harvest Time and Pruning Technique on Total CBD Concentration and Yield of Medicinal Cannabis
Danilo Crispim Massuela,Jens Hartung,Sebastian Munz,Federico Erpenbach,Simone Graeff-Hönninger +4 more
TL;DR: Investigation of the impact of harvest time and pruning techniques on plant biomass accumulation, CBD and CBDA-concentrations and total CBD yield of a chemotype III medical cannabis genotype under indoor cultivation showed that inflorescence dry weight increased continuously, while the total CBD concentration did not differ significantly over time.
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