Journal ArticleDOI
Creating, transporting, cutting, and merging liquid droplets by electrowetting-based actuation for digital microfluidic circuits
TLDR
In this paper, the authors report the completion of four fundamental fluidic operations considered essential to build digital microfluidic circuits, which can be used for lab-on-a-chip or micro total analysis system (/spl mu/TAS): 1) creating, 2) transporting, 3) cutting, and 4) merging liquid droplets, all by electrowetting.Abstract:
Reports the completion of four fundamental fluidic operations considered essential to build digital microfluidic circuits, which can be used for lab-on-a-chip or micro total analysis system (/spl mu/TAS): 1) creating, 2) transporting, 3) cutting, and 4) merging liquid droplets, all by electrowetting, i.e., controlling the wetting property of the surface through electric potential. The surface used in this report is, more specifically, an electrode covered with dielectrics, hence, called electrowetting-on-dielectric (EWOD). All the fluidic movement is confined between two plates, which we call parallel-plate channel, rather than through closed channels or on open surfaces. While transporting and merging droplets are easily verified, we discover that there exists a design criterion for a given set of materials beyond which the droplet simply cannot be cut by EWOD mechanism. The condition for successful cutting is theoretically analyzed by examining the channel gap, the droplet size and the degree of contact angle change by electrowetting on dielectric (EWOD). A series of experiments is run and verifies the criterion.read more
Citations
More filters
Proceedings ArticleDOI
Towards fault-tolerant digital microfluidic lab-on-chip: Defects, fault modeling, testing, and reconfiguration
TL;DR: A survey of early work on fault tolerance in digital microfluidic lab-on-chip systems is presented in this paper, where the authors present a test technique for both traditional shorts and opens and logical fault models that can be viewed not only in terms of traditional shorts but also target biochip functionality.
Journal ArticleDOI
A compact 3D-printed interface for coupling open digital microchips with Venturi easy ambient sonic-spray ionization mass spectrometry
TL;DR: This work presents a facile method for coupling open DMF microchips to mass spectrometers using Venturi easy ambient sonic-spray ionization operated at atmospheric pressure and incorporates a touch-screen panel and remote control for user-friendly operation.
Journal ArticleDOI
Directional Droplet Transport on Functional Surfaces with Superwettabilities
Patent
Methods and Apparatuses for Chip-Based DNA Error Reduction
TL;DR: In this paper, the mismatch-containing cleaved heteroduplexes can be removed from the microarray chip using a global buffer exchange, which can be used for a variety of applications, including synthesis of biofuels and value-added pharmaceutical products.
Journal ArticleDOI
pH‐ and Voltage‐Switchable Superhydrophobic Surfaces by Electro‐Copolymerization of EDOT Derivatives Containing Carboxylic Acids and Long Alkyl Chains
TL;DR: In order to produce pH- and voltage-switchable superhydrophobic surfaces, PEDOT derivatives containing various proportions of a EDot monomer containing carboxylic groups (EDOT-COOH) and EDOT monomer-containing dodecyl chains ( EDOT-O-H12) are elaborated.
References
More filters
Book
Fundamentals of microfabrication
TL;DR: The second edition of the Fundamentals of Microfabrication as discussed by the authors provides an in-depth coverage of the science of miniaturization, its methods, and materials, from the fundamentals of lithography through bonding and packaging to quantum structures and molecular engineering.
Journal ArticleDOI
Electrowetting-based actuation of liquid droplets for microfluidic applications
TL;DR: In this article, a microactuator for rapid manipulation of discrete microdroplets is presented, which is accomplished by direct electrical control of the surface tension through two sets of opposing planar electrodes fabricated on glass.
Book
Micromachined Transducers Sourcebook
TL;DR: In this paper, the authors present an overview of Micromachining Techniques, Mechanical Transducers, Optical Transducers and Ionizing Radiation Transducers for Microfluidic Devices.
Journal ArticleDOI
Electrowetting-based actuation of droplets for integrated microfluidics
TL;DR: In this paper, an alternative approach to microfluidics based upon the micromanipulation of discrete droplets of aqueous electrolyte by electrowetting is reported.