Journal ArticleDOI
Creating, transporting, cutting, and merging liquid droplets by electrowetting-based actuation for digital microfluidic circuits
TLDR
In this paper, the authors report the completion of four fundamental fluidic operations considered essential to build digital microfluidic circuits, which can be used for lab-on-a-chip or micro total analysis system (/spl mu/TAS): 1) creating, 2) transporting, 3) cutting, and 4) merging liquid droplets, all by electrowetting.Abstract:
Reports the completion of four fundamental fluidic operations considered essential to build digital microfluidic circuits, which can be used for lab-on-a-chip or micro total analysis system (/spl mu/TAS): 1) creating, 2) transporting, 3) cutting, and 4) merging liquid droplets, all by electrowetting, i.e., controlling the wetting property of the surface through electric potential. The surface used in this report is, more specifically, an electrode covered with dielectrics, hence, called electrowetting-on-dielectric (EWOD). All the fluidic movement is confined between two plates, which we call parallel-plate channel, rather than through closed channels or on open surfaces. While transporting and merging droplets are easily verified, we discover that there exists a design criterion for a given set of materials beyond which the droplet simply cannot be cut by EWOD mechanism. The condition for successful cutting is theoretically analyzed by examining the channel gap, the droplet size and the degree of contact angle change by electrowetting on dielectric (EWOD). A series of experiments is run and verifies the criterion.read more
Citations
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Journal ArticleDOI
Manipulation of droplets and bubbles for thermal applications
TL;DR: In this paper , the dynamics of droplets and bubbles during phase change including nucleation, growth, and departure critically influence the thermal transport performance and system efficiency, highlighting recent advancements using static and dynamic strategies.
Journal ArticleDOI
Triboelectric wetting for continuous droplet transport
Wanghuai Xu,Yuankai Jin,Wanbo Li,Yuxin Song,Shouwei Gao,Baoping Zhang,Lili Wang,Miao Miao Cui,Xiantong Yan,Zuankai Wang +9 more
TL;DR: In this article , the authors developed a largely unexplored triboelectric wetting (TEW) phenomenon that can directly exploit the tribolectric charges to achieve the programmed and precise water droplet control.
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Role of Digital Microfluidics in Enabling Access to Laboratory Automation and Making Biology Programmable
TL;DR: How the function of a DMF device within a fully integrated pipeline for the production of novel organisms and biomolecules is highly dependent on integration with different sensing techniques and methodologies from machine learning and big data is discussed.
Journal ArticleDOI
Open-atmosphere sustenance of highly volatile attoliter-size droplets on surfaces
TL;DR: A unique microfluidic paradigm in which microscopic volatile droplets are formed, sustained, and manipulated in size and content at any desired spot on unpatterned substrates is introduced, which introduces a high degree of flexibility and make it pertinent to a diverse range of applications.
Journal ArticleDOI
Fluidic conduits for highly efficient purification of target species in EWOD-driven droplet microfluidics
TL;DR: This work achieves high-purity separation for the case of electrowetting-on-dielectric (EWOD) based droplet microfluidics by introducing a "fluidic conduit" between a sample droplet and a buffer droplet controlled by EWOD.
References
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Fundamentals of microfabrication
TL;DR: The second edition of the Fundamentals of Microfabrication as discussed by the authors provides an in-depth coverage of the science of miniaturization, its methods, and materials, from the fundamentals of lithography through bonding and packaging to quantum structures and molecular engineering.
Journal ArticleDOI
Electrowetting-based actuation of liquid droplets for microfluidic applications
TL;DR: In this article, a microactuator for rapid manipulation of discrete microdroplets is presented, which is accomplished by direct electrical control of the surface tension through two sets of opposing planar electrodes fabricated on glass.
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TL;DR: In this paper, the authors present an overview of Micromachining Techniques, Mechanical Transducers, Optical Transducers and Ionizing Radiation Transducers for Microfluidic Devices.
Journal ArticleDOI
Electrowetting-based actuation of droplets for integrated microfluidics
TL;DR: In this paper, an alternative approach to microfluidics based upon the micromanipulation of discrete droplets of aqueous electrolyte by electrowetting is reported.