Journal ArticleDOI
Creating, transporting, cutting, and merging liquid droplets by electrowetting-based actuation for digital microfluidic circuits
TLDR
In this paper, the authors report the completion of four fundamental fluidic operations considered essential to build digital microfluidic circuits, which can be used for lab-on-a-chip or micro total analysis system (/spl mu/TAS): 1) creating, 2) transporting, 3) cutting, and 4) merging liquid droplets, all by electrowetting.Abstract:
Reports the completion of four fundamental fluidic operations considered essential to build digital microfluidic circuits, which can be used for lab-on-a-chip or micro total analysis system (/spl mu/TAS): 1) creating, 2) transporting, 3) cutting, and 4) merging liquid droplets, all by electrowetting, i.e., controlling the wetting property of the surface through electric potential. The surface used in this report is, more specifically, an electrode covered with dielectrics, hence, called electrowetting-on-dielectric (EWOD). All the fluidic movement is confined between two plates, which we call parallel-plate channel, rather than through closed channels or on open surfaces. While transporting and merging droplets are easily verified, we discover that there exists a design criterion for a given set of materials beyond which the droplet simply cannot be cut by EWOD mechanism. The condition for successful cutting is theoretically analyzed by examining the channel gap, the droplet size and the degree of contact angle change by electrowetting on dielectric (EWOD). A series of experiments is run and verifies the criterion.read more
Citations
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Journal ArticleDOI
Two-dimensional magnetic manipulation of microdroplets on a chip as a platform for bioanalytical applications
Ulrike Lehmann,Smail Hadjidj,Virendra K. Parashar,Caroline Vandevyver,Amar Rida,Martin A. M. Gijs +5 more
TL;DR: In this article, a system for the 2D magnetic manipulation of aqueous droplets suspended in silicone oil is presented for on-chip bio-analysis, where three-dimensional surface structures are replaced by an optimized hydrophilic/hydrophobic patterning of the chip surface to facilitate droplet splitting.
Journal ArticleDOI
Design of hydrophobic surfaces for liquid droplet control
TL;DR: A review of recent studies investigating the design of hydrophobic surfaces for liquid droplet control, specifically focussing on recent studies of dynamic hydrophobicity is presented in this paper.
Journal ArticleDOI
Modeling and Controlling Parallel Tasks in Droplet-Based Microfluidic Systems
TL;DR: This paper presents general hardware-independent models and algorithms to automate the operation of droplet-based microfluidic systems and an approach toward automatic mapping of a biochemical analysis task onto a DMFS is investigated.
Journal ArticleDOI
Manipulation of droplets in microfluidic systems
TL;DR: The droplet in a microfluidics system can be seen as an isolated reactor, with low consumption of samples and reagents, minimal dispersion and flexible control.
PatentDOI
Single sided continuous optoelectrowetting (SCEOW) device for droplet manipulation with light patterns
Pei-Yu Chiou,Sung-Yong Park +1 more
TL;DR: In this article, a single-sided continuous optoelectrowetting (SCOEW) device for manipulating droplets retained in a fluid over the SCOEW device with dynamic patterns of low intensity light, such as from a display screen, is described.
References
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Book
Fundamentals of microfabrication
TL;DR: The second edition of the Fundamentals of Microfabrication as discussed by the authors provides an in-depth coverage of the science of miniaturization, its methods, and materials, from the fundamentals of lithography through bonding and packaging to quantum structures and molecular engineering.
Journal ArticleDOI
Electrowetting-based actuation of liquid droplets for microfluidic applications
TL;DR: In this article, a microactuator for rapid manipulation of discrete microdroplets is presented, which is accomplished by direct electrical control of the surface tension through two sets of opposing planar electrodes fabricated on glass.
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Micromachined Transducers Sourcebook
TL;DR: In this paper, the authors present an overview of Micromachining Techniques, Mechanical Transducers, Optical Transducers and Ionizing Radiation Transducers for Microfluidic Devices.
Journal ArticleDOI
Electrowetting-based actuation of droplets for integrated microfluidics
TL;DR: In this paper, an alternative approach to microfluidics based upon the micromanipulation of discrete droplets of aqueous electrolyte by electrowetting is reported.