Journal ArticleDOI
Creating, transporting, cutting, and merging liquid droplets by electrowetting-based actuation for digital microfluidic circuits
TLDR
In this paper, the authors report the completion of four fundamental fluidic operations considered essential to build digital microfluidic circuits, which can be used for lab-on-a-chip or micro total analysis system (/spl mu/TAS): 1) creating, 2) transporting, 3) cutting, and 4) merging liquid droplets, all by electrowetting.Abstract:
Reports the completion of four fundamental fluidic operations considered essential to build digital microfluidic circuits, which can be used for lab-on-a-chip or micro total analysis system (/spl mu/TAS): 1) creating, 2) transporting, 3) cutting, and 4) merging liquid droplets, all by electrowetting, i.e., controlling the wetting property of the surface through electric potential. The surface used in this report is, more specifically, an electrode covered with dielectrics, hence, called electrowetting-on-dielectric (EWOD). All the fluidic movement is confined between two plates, which we call parallel-plate channel, rather than through closed channels or on open surfaces. While transporting and merging droplets are easily verified, we discover that there exists a design criterion for a given set of materials beyond which the droplet simply cannot be cut by EWOD mechanism. The condition for successful cutting is theoretically analyzed by examining the channel gap, the droplet size and the degree of contact angle change by electrowetting on dielectric (EWOD). A series of experiments is run and verifies the criterion.read more
Citations
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Journal ArticleDOI
Electrowetting droplet microfluidics on a single planar surface
TL;DR: In this article, the authors demonstrate an electrowetting system in which the droplet can be electrically grounded from below using thin conductive lines on top of the dielectric layer.
Journal ArticleDOI
Dispensing nano-pico droplets and liquid patterning by pyroelectrodynamic shooting
TL;DR: A simple way to draw attolitre liquid droplets from one or multiple sessile drops or liquid film reservoirs using a pyroelectrohydrodynamic dispenser, which is expected to have many applications in biochemical assays and various transport and mixing processes.
Journal ArticleDOI
Droplet-based DNA purification in a magnetic lab-on-a-chip.
TL;DR: The system is able to extract genomic material from dilute cell samples by using the actuation of magnetic microparticles within the droplet-based DNA purification through a matrix of coils.
Journal ArticleDOI
Hydration behavior under confinement by nanoscale surfaces with patterned hydrophobicity and hydrophilicity
TL;DR: In this article, molecular dynamics simulations of water confined between nanoscale surfaces (≈3.2 × 3.2 nm2) with various patterns of hydrophobicity and hydrophilicity at T = 300 K, −0.05 GPa ≤ P ≤ 0.2 GPa, and plate separations 0.5 nm ≤ d ≤ 1.6 nm.
Journal ArticleDOI
Magnetic digital microfluidics – a review
Yi Zhang,Nam-Trung Nguyen +1 more
TL;DR: Various methods of droplet manipulation using magnetic forces are discussed, ranging from conventional magnetic particle-based actuation to the recent development of ferrofluids and magnetic liquid marbles.
References
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TL;DR: The second edition of the Fundamentals of Microfabrication as discussed by the authors provides an in-depth coverage of the science of miniaturization, its methods, and materials, from the fundamentals of lithography through bonding and packaging to quantum structures and molecular engineering.
Journal ArticleDOI
Electrowetting-based actuation of liquid droplets for microfluidic applications
TL;DR: In this article, a microactuator for rapid manipulation of discrete microdroplets is presented, which is accomplished by direct electrical control of the surface tension through two sets of opposing planar electrodes fabricated on glass.
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TL;DR: In this paper, the authors present an overview of Micromachining Techniques, Mechanical Transducers, Optical Transducers and Ionizing Radiation Transducers for Microfluidic Devices.
Journal ArticleDOI
Electrowetting-based actuation of droplets for integrated microfluidics
TL;DR: In this paper, an alternative approach to microfluidics based upon the micromanipulation of discrete droplets of aqueous electrolyte by electrowetting is reported.